Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marek Kravec"'
Autor:
Anna Vyhlídalová Kotrbová, Kristína Gömöryová, Antónia Mikulová, Hana Plešingerová, Stanislava Sladeček, Marek Kravec, Šárka Hrachovinová, David Potěšil, Garett Dunsmore, Camille Blériot, Mathilde Bied, Jan Kotouček, Markéta Bednaříková, Jitka Hausnerová, Luboš Minář, Igor Crha, Michal Felsinger, Zbyněk Zdráhal, Florent Ginhoux, Vít Weinberger, Vitězslav Bryja, Vendula Pospíchalová
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract High‐grade serous carcinoma of the ovary, fallopian tube and peritoneum (HGSC), the most common type of ovarian cancer, ranks among the deadliest malignancies. Many HGSC patients have excess fluid in the peritoneum called ascites. Ascites
Externí odkaz:
https://doaj.org/article/dc1667b33f2d4fcab8e36f032b4b3b53
Autor:
Kateřina Hanáková, Ondřej Bernatík, Marek Kravec, Miroslav Micka, Jitender Kumar, Jakub Harnoš, Petra Ovesná, Petra Paclíková, Matěj Rádsetoulal, David Potěšil, Konstantinos Tripsianes, Lukáš Čajánek, Zbyněk Zdráhal, Vítězslav Bryja
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation gene
Externí odkaz:
https://doaj.org/article/59bcf25501ed4898813e2a7a806d2bac
Autor:
Jakub Harnoš, Maria Consuelo Alonso Cañizal, Miroslav Jurásek, Jitender Kumar, Cornelia Holler, Alexandra Schambony, Kateřina Hanáková, Ondřej Bernatík, Zbyněk Zdráhal, Kristína Gömöryová, Tomáš Gybeľ, Tomasz Witold Radaszkiewicz, Marek Kravec, Lukáš Trantírek, Jan Ryneš, Zankruti Dave, Ana Iris Fernández-Llamazares, Robert Vácha, Konstantinos Tripsianes, Carsten Hoffmann, Vítězslav Bryja
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Dishevelled (DVL) is the key component of Wnt signaling pathway that acts as a signaling hub. Here, authors study the conformational dynamics of DVL3 in vivo using their engineered FlAsH-based FRET biosensors and describe how Wnt activation opens DVL
Externí odkaz:
https://doaj.org/article/c656ec6d84244ea4ba47e39232d91995
Autor:
Anna Kotrbová, Karel Štěpka, Martin Maška, Jakub Jozef Pálenik, Ladislav Ilkovics, Dobromila Klemová, Marek Kravec, František Hubatka, Zankruti Dave, Aleš Hampl, Vítězslav Bryja, Pavel Matula, Vendula Pospíchalová
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Extracellular vesicles (EVs) function as important conveyers of information between cells and thus can be exploited as drug delivery systems or disease biomarkers. Transmission electron microscopy (TEM) remains the gold standard method for visualisat
Externí odkaz:
https://doaj.org/article/e8422357174045708c3588dd84e57d8e
Autor:
Francesco L, Falginella, Marek, Kravec, Martina, Drabinová, Petra, Paclíková, Vítĕzslav, Bryja, Robert, Vácha
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1864:183983
Over the past decades an extensive effort has been made to provide a more comprehensive understanding of Wnt signaling, yet many regulatory and structural aspects remain elusive. Among these, the ability of Dishevelled (DVL) protein to relocalize at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91b6c32bbf0aaddd5a05c8cbcba6875
https://doi.org/10.1016/j.bbamem.2022.183983
https://doi.org/10.1016/j.bbamem.2022.183983
Autor:
Miroslav Micka, Matěj Rádsetoulal, Kateřina Hanáková, Petra Paclíková, Jakub Harnoš, Ondřej Bernatík, Petra Ovesná, Lukas Cajanek, Konstantinos Tripsianes, David Potěšil, Jitender Kumar, Zbyněk Zdráhal, Marek Kravec, Vítězslav Bryja
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
BackgroundDishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation generates comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0017372521a710f20157736618ecedae
https://doi.org/10.1186/s12964-019-0470-z
https://doi.org/10.1186/s12964-019-0470-z
Autor:
Alexandra Schambony, Tomasz Witold Radaszkiewicz, Maria Consuelo Alonso Cañizal, Robert Vácha, Jan Ryneš, Konstantinos Tripsianes, Jitender Kumar, Carsten Hoffmann, Zbyněk Zdráhal, Kateřina Hanáková, Zankruti Dave, Lukáš Trantírek, Miroslav Jurásek, Ana Iris Fernández-Llamazares, Jakub Harnoš, Marek Kravec, Cornelia Holler, Ondřej Bernatík, Vítězslav Bryja, Tomáš Gybeľ, Kristína Gömöryová
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications
Nature Communications
Dishevelled (DVL) is the key component of the Wnt signaling pathway. Currently, DVL conformational dynamics under native conditions is unknown. To overcome this limitation, we develop the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5af2d2100c7aaed0c7ee83d894e2a39
https://doi.org/10.1038/s41467-019-09651-7
https://doi.org/10.1038/s41467-019-09651-7
Autor:
František Hubatka, Anna Kotrbova, Ladislav Ilkovics, Marek Kravec, Aleš Hampl, Vendula Pospichalova, Juraj Pálenik, Vítězslav Bryja, Zankruti Dave, Karel Štěpka, Dobromila Klemová, Martin Maška, Pavel Matula
Publikováno v:
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Extracellular vesicles (EVs) function as important conveyers of information between cells and thus can be exploited as drug delivery systems or disease biomarkers. Transmission electron microscopy (TEM) remains the gold standard method for visualisat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4477a492fe13379b7fb17b76eeae3f3a
http://europepmc.org/articles/PMC6346710
http://europepmc.org/articles/PMC6346710