Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marek J. Noga"'
Autor:
Johan F. A. Pijnenborg, Emiel Rossing, Jona Merx, Marek J. Noga, Willem H. C. Titulaer, Nienke Eerden, Raisa Veizaj, Paul B. White, Dirk J. Lefeber, Thomas J. Boltje
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Aberrant expression of fucosylated glycans has been linked to several disease states. Control of fucose expression on live cells is needed to aid research and therapy development. Here the authors report on the development of a class of fucosylation
Externí odkaz:
https://doaj.org/article/f75d0352f311415b8d2a6f71407cf0de
Autor:
Federica Conte, Marek J. Noga, Monique van Scherpenzeel, Raisa Veizaj, Rik Scharn, Juda-El Sam, Chiara Palumbo, Frans C. A. van den Brandt, Christian Freund, Eduardo Soares, Huiqing Zhou, Dirk J. Lefeber
Publikováno v:
Cells, Vol 12, Iss 13, p 1765 (2023)
Metabolism not only produces energy necessary for the cell but is also a key regulator of several cellular functions, including pluripotency and self-renewal. Nucleotide sugars (NSs) are activated sugars that link glucose metabolism with cellular fun
Externí odkaz:
https://doaj.org/article/ed7d94ffbd454f9c961218eac0c44815
Autor:
Federica Conte, Angel Ashikov, Rachel Mijdam, Eline G. P. van de Ven, Monique van Scherpenzeel, Raisa Veizaj, Seyed P. Mahalleh-Yousefi, Merel A. Post, Karin Huijben, Daan M. Panneman, Richard J. T. Rodenburg, Nicol C. Voermans, Alejandro Garanto, Werner J. H. Koopman, Hans J. C. T. Wessels, Marek J. Noga, Dirk J. Lefeber
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8247 (2023)
Phosphoglucomutase 1 (PGM1) is a key enzyme for the regulation of energy metabolism from glycogen and glycolysis, as it catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate. PGM1 deficiency is an autosomal recessive disorder c
Externí odkaz:
https://doaj.org/article/764ad37d103c4846adf3b11e0471176b
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The molecule guanosine tetraphophosphate (ppGpp) is most commonly considered an alarmone produced during acute stress. However, ppGpp is also present at low concentrations during steady-state growth. Whether ppGpp controls the same cellular targets a
Externí odkaz:
https://doaj.org/article/fda46a59e94f4a20b30d263c874f504d
Autor:
Marek J. Noga, Ferhat Büke, Niels J. F. van den Broek, Nicole C. E. Imholz, Nicole Scherer, Flora Yang, Gregory Bokinsky
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Every cell must produce enough membrane to contain itself. However, the mechanisms by which the rate of membrane synthesis is coupled with the rate of cell growth remain unresolved. By comparing substrate and enzyme concentrations of the fat
Externí odkaz:
https://doaj.org/article/1a339936fa9549dbb9bf53ce45f0fd53
Autor:
Lefeber, Federica Conte, Marek J. Noga, Monique van Scherpenzeel, Raisa Veizaj, Rik Scharn, Juda-El Sam, Chiara Palumbo, Frans C. A. van den Brandt, Christian Freund, Eduardo Soares, Huiqing Zhou, Dirk J.
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1765
Metabolism not only produces energy necessary for the cell but is also a key regulator of several cellular functions, including pluripotency and self-renewal. Nucleotide sugars (NSs) are activated sugars that link glucose metabolism with cellular fun
Autor:
Raisa Veizaj, Johan F. A. Pijnenborg, Thomas J. Boltje, Eline A. Visser, Dirk Lefeber, Christian Büll, Emiel Rossing, Marek J Noga
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry : a European Journal, 27, 4022-4027
Chemistry : a European Journal, 27, 12, pp. 4022-4027
Chemistry : a European Journal, 27, 4022-4027
Chemistry : a European Journal, 27, 12, pp. 4022-4027
Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a potential therapeutic avenue for example in cancer, inflammation, and infection. In this study, we found that protected
Autor:
Marek J Noga, Johan F. A. Pijnenborg, Nienke Eerden, Jona Merx, Thomas J. Boltje, Emiel Rossing, Raisa Veizaj, Willem H C Titulaer, Dirk Lefeber, Paul B. White
Publikováno v:
Nature Communications
Nature Communications, 12, 1, pp. 1-9
Nature Communications, 12, 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, 12, 1, pp. 1-9
Nature Communications, 12, 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The sugar fucose is expressed on mammalian cell membranes as part of glycoconjugates and mediates essential physiological processes. The aberrant expression of fucosylated glycans has been linked to pathologies such as cancer, inflammation, infection
Autor:
Raisa Veizaj, Willem H C Titulaer, Dirk Lefeber, Marek J. Noga, Thomas J. Boltje, Emiel Rossing, Johan F. A. Pijnenborg
Fucose sugars are expressed on mammalian cell membranes as part of glycoconjugates and mediates essential physiological processes. The aberrant expression of fucosylated glycans has been linked to pathologies such as cancer, inflammation, infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6929c7f21081007a5a449ca869f7464
https://doi.org/10.26434/chemrxiv.13082138.v1
https://doi.org/10.26434/chemrxiv.13082138.v1
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, 11
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, 11
Frontiers in Microbiology, Vol 11 (2020)
The molecule guanosine tetraphophosphate (ppGpp) is most commonly considered an alarmone produced during acute stress. However, ppGpp is also present at low concentrations during steady-state growth. Whether ppGpp controls the same cellular targets a