Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Marek Foksinski"'
Autor:
Jolanta Guz, Ewelina Zarakowska, Pawel Mijewski, Aleksandra Wasilow, Fabian Lesniewski, Marek Foksinski, Bartosz Brzoszczyk, Piotr Jarzemski, Daniel Gackowski, Ryszard Olinski
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 58, Iss , Pp 101079- (2024)
Objectives: Benign Prostatic Hyperplasia (BPH) and Prostate Cancer (PC) are very common pathologies among aging men. Both disorders involve aberrant cell division and differentiation within the prostate gland. However, the direct link between these t
Externí odkaz:
https://doaj.org/article/0220cc75a14241fa9817d53c67cd9184
Autor:
Rafal Rozalski, Daniel Gackowski, Aleksandra Skalska-Bugala, Marta Starczak, Agnieszka Siomek-Gorecka, Ewelina Zarakowska, Martyna Modrzejewska, Tomasz Dziaman, Anna Szpila, Kinga Linowiecka, Jolanta Guz, Justyna Szpotan, Maciej Gawronski, Anna Labejszo, Lidia Gackowska, Marek Foksinski, Elwira Olinska, Aleksandra Wasilow, Andrzej Koltan, Jan Styczynski, Ryszard Olinski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The active DNA demethylation process may be linked to aberrant methylation and may be involved in leukemogenesis. We investigated the role of epigenetic DNA modifications in childhood acute lymphoblastic leukemia (ALL) diagnostics and therap
Externí odkaz:
https://doaj.org/article/d02605d847f64fd8a67d0da5db68e4ac
Autor:
Marta Starczak, Ewelina Zarakowska, Martyna Modrzejewska, Tomasz Dziaman, Anna Szpila, Kinga Linowiecka, Jolanta Guz, Justyna Szpotan, Maciej Gawronski, Anna Labejszo, Ariel Liebert, Zbigniew Banaszkiewicz, Maria Klopocka, Marek Foksinski, Daniel Gackowski, Ryszard Olinski
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background A characteristic feature of malignant cells, such as colorectal cancer cells, is a profound decrease in the level of 5-hydroxymethylcytosine, a product of 5-methylcytosine oxidation by TET enzymes. Recent studies showed that ascor
Externí odkaz:
https://doaj.org/article/507636277e8b48f1a1b4f317954fc4dc
Autor:
Tomasz Dziaman, Daniel Gackowski, Jolanta Guz, Kinga Linowiecka, Magdalena Bodnar, Marta Starczak, Ewelina Zarakowska, Martyna Modrzejewska, Anna Szpila, Justyna Szpotan, Maciej Gawronski, Anna Labejszo, Ariel Liebert, Zbigniew Banaszkiewicz, Maria Klopocka, Marek Foksinski, Andrzej Marszalek, Ryszard Olinski
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)
Abstract Background Active demethylation of 5-methyl-2′-deoxycytidine (5-mdC) in DNA occurs by oxidation to 5-(hydroxymethyl)-2′-deoxycytidine (5-hmdC) and further oxidation to 5-formyl-2′-deoxycytidine (5-fdC) and 5-carboxy-2′-deoxycytidine
Externí odkaz:
https://doaj.org/article/fd38b53e8df744ab9c03def9dba142b4
Autor:
Marek Foksinski, Ewelina Zarakowska, Daniel Gackowski, Magdalena Skonieczna, Karolina Gajda, Dorota Hudy, Anna Szpila, Karol Bialkowski, Marta Starczak, Anna Labejszo, Jaroslaw Czyz, Joanna Rzeszowska-Wolny, Ryszard Olinski
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195819 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0188856.].
Externí odkaz:
https://doaj.org/article/bfe567fd5ad9449ea91d337a4387b652
Autor:
Marek Foksinski, Ewelina Zarakowska, Daniel Gackowski, Magdalena Skonieczna, Karolina Gajda, Dorota Hudy, Anna Szpila, Karol Bialkowski, Marta Starczak, Anna Labejszo, Jaroslaw Czyz, Joanna Rzeszowska-Wolny, Ryszard Olinski
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188856 (2017)
Active demethylation of 5-methylcytosine moiety in DNA occurs by its sequential oxidation to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, catalysed by enzymes of the Ten-Eleven Translocation family proteins (TETs 1, 2 and 3). Here
Externí odkaz:
https://doaj.org/article/a7f2ed3061a14863b91a8d82c49db149
Autor:
Jolanta Guz, Daniel Gackowski, Marek Foksinski, Rafal Rozalski, Ewelina Zarakowska, Agnieszka Siomek, Anna Szpila, Marcin Kotzbach, Roman Kotzbach, Ryszard Olinski
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68490 (2013)
Abnormal spermatozoa frequently display typical features of oxidative stress, i.e. excessive level of reactive oxygen species (ROS) and depleted antioxidant capacity. Moreover, it has been found that a high level of oxidatively damaged DNA is associa
Externí odkaz:
https://doaj.org/article/8e62fa446814452f95683fe329e7fadc
Autor:
Marek Foksinski, Rafal Rozalski, Justyna Szpotan, Marta Starczak, Ewelina Zarakowska, Ryszard Olinski, Agnieszka Siomek-Gorecka, Jolanta Guz, Tomasz Dziaman, Kinga Linowiecka, Lidia Gackowska, Elwira Olinska, Aleksandra Wasilow, Aleksandra Skalska-Bugala, Anna Szpila, Anna Labejszo, Jan Styczyński, Martyna Modrzejewska, Andrzej Kołtan, Daniel Gackowski, Maciej Gawronski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The active DNA demethylation process may be linked to aberrant methylation and may be involved in leukemogenesis. We investigated the role of epigenetic DNA modifications in childhood acute lymphoblastic leukemia (ALL) diagnostics and therapy monitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84a700a54e5c243786124c148c20789
https://doaj.org/article/d02605d847f64fd8a67d0da5db68e4ac
https://doaj.org/article/d02605d847f64fd8a67d0da5db68e4ac
Autor:
Kinga Linowiecka, Jolanta Guz, Tomasz Dziaman, Olga Urbanowska–Domańska, Ewelina Zarakowska, Anna Szpila, Justyna Szpotan, Aleksandra Skalska-Bugała, Paweł Mijewski, Agnieszka Siomek-Górecka, Rafał Różalski, Daniel Gackowski, Ryszard Oliński, Marek Foksiński
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The active DNA demethylation process, which involves TET proteins, can affect DNA methylation pattern. TET dependent demethylation results in DNA hypomethylation by oxidation 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) and its
Externí odkaz:
https://doaj.org/article/053fb1701c4342bb97c30e788417e492
Publikováno v:
Contemporary Oncology, Vol 23, Iss 2, Pp 74-80 (2019)
Contemporary Oncology
Contemporary Oncology
Alterations in DNA methylation may cause disturbances in regulation of gene expression, including drug metabolism and distribution. Moreover, many cancers, including breast cancer, are characterized by DNA hypomethylation and a decreased 5-hydroxymet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c17742d32f52ee2e8bdc9d9f549d9d
https://doi.org/10.5114/wo.2019.85200
https://doi.org/10.5114/wo.2019.85200