Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marek Dziki"'
Autor:
Waldemar A. Turski, M Kozicka, Zdzisław Kleinrok, Jolanta Parada-Turska, Czuczwar Sj, Rafal M. Kaminski, Marek Dziki
Publikováno v:
Pharmacological Research. 37:375-381
Prostaglandins and their inhibitors may affect convulsive phenomena. Thus, the aim of this study was to examine possible interactions between non-steroidal anti-inflammatory drugs and two conventional antiepileptic drugs in terms of their anticonvuls
Autor:
Grażyna Czechowska, Waldemar A. Turski, Stanisław J. Czuczwar, Marek Dziki, T. Pietrasiewicz, Zdzisław Kleinrok
Publikováno v:
European Journal of Pharmacology. 250:1-7
CGP 37849 (1 mg/kg i.p.) enhanced the protective action of carbamazepine, diphenylhydantoin and phenobarbital against maximal electroshock-induced convulsions in mice. At 0.25 mg/kg CGP 37849 was inactive and at 0.5 mg/kg it potentiated the anticonvu
Publikováno v:
European Journal of Pharmacology. 222:273-278
The effects of combined treatment with low doses (0.025-0.05 mg/kg i.p.) of the non-competitive NMDA receptor antagonist, MK-801 (dizocilpine), and the antiepileptic drug, valproate, were studied in amygdala-kindled and non-kindled rats. MK-801, 0.05
Publikováno v:
Developmental Brain Research. 67:137-144
Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats. Highest susceptibility to AOAA seizures was observed in 7–14-day-old rat pups. The lowest susceptibility was recorded in 10–2
Autor:
Esper A. Cavalheiro, Marek Dziki, Lineu S. Calderazzo-Filho, Ewa M. Urbańska, Waldemar A. Turski
Publikováno v:
Synapse. 7:173-180
Systemic (s.c.) administration of aminooxyacetic acid (AOAA) in mice triggered clonic convulsions with a CD50 (convulsive dose) of 68 mg/kg (range 54-86). AOAA also induced clonic convulsions in mice subjected to intracerebroventricular administratio
Autor:
Waldemar A. Turski, Chrysanthy Ikonomidou, Ewa M. Urbańska, Jolanta Parada-Turska, Marek Dziki
Publikováno v:
Brain Research. 514:131-134
The effects of excitatory amino acid antagonists on convulsions induced by intracerebroventricular (i.c.v.) or systemic (s.c.) administration of the gamma-aminobutyric acidA (GABAA) antagonist bicuculline (BIC) were tested in mice. 3-[+/-)-2-Carboxyp
Publikováno v:
Neuropharmacology. 31(10)
Memantine increased the threshold for electroconvulsions, when administered at 1.0–6.0 mg/kg (i.p.) and given in subthreshold dosesof 0.0156, 0.0625, 0.125 and 0.5 mg/kg (i.p.) potentiated the protective efficacy of valproate, against maximal elect
Publikováno v:
European journal of pharmacology. 200(2-3)
MK-801 (a potent non-competitive antagonist of N-methyl-D-aspartic acid-mediated events) in subcutanteous doses of 0.1 and 0.2 mg/kg increased the threshold for electroconvulsions and in doses of 0.0031 and 0.0125 mg/kg enhanced the protective activi