Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus.

Autor: Dierk Wanke, Mareike L Hohenstatt, Marek Dynowski, Ulrich Bloss, Andreas Hecker, Kirstin Elgass, Sabine Hummel, Achim Hahn, Katharina Caesar, Frank Schleifenbaum, Klaus Harter, Kenneth W Berendzen

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e16070 (2011)

GAGA-motif binding proteins control transcriptional activation or repression of homeotic genes. Interestingly, there are no sequence similarities between animal and plant proteins. Plant BBR/BPC-proteins can be classified into two distinct groups: Pr

Externí odkaz: https://doaj.org/article/53d11158e7fc47d990612b7d1897191f

Supplementary Figure 1 from Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

Autor: Crispin Miller, Richard Marais, Caroline Dive, Ged Brady, Kristopher K. Frese, Marek Dynowski, Christopher Wirth, Sam Taylor, Christopher Smowton, María Romina Girotti, Garima Khandelwal

Overview of data processing pipeline.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3680520db95274913ea778dcbc69d725
https://doi.org/10.1158/1541-7786.22516266

Supplementary Figure 3 from Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

Autor: Crispin Miller, Richard Marais, Caroline Dive, Ged Brady, Kristopher K. Frese, Marek Dynowski, Christopher Wirth, Sam Taylor, Christopher Smowton, María Romina Girotti, Garima Khandelwal

Differences in fold change between primary tumour and CDXF1 before and after processing using Xenome.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2281fa49ef1934f612f1521e573ca5b1
https://doi.org/10.1158/1541-7786.22516260.v1

Data from Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

Autor: Crispin Miller, Richard Marais, Caroline Dive, Ged Brady, Kristopher K. Frese, Marek Dynowski, Christopher Wirth, Sam Taylor, Christopher Smowton, María Romina Girotti, Garima Khandelwal

Patient-derived xenograft (PDX) and circulating tumor cell–derived explant (CDX) models are powerful methods for the study of human disease. In cancer research, these methods have been applied to multiple questions, including the study of metastati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::feb474445834cdef2de35469336629ad
https://doi.org/10.1158/1541-7786.c.6541329

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Autor: Saba Ferdous, Charles Swanton, Francesca Chemi, Chang Sik Kim, Selvaraju Veeriah, Ged Brady, Sakshi Gulati, Deborah J. Burt, Mariam Jamal-Hanjani, Fiona H Blackhall, Daniel Slane-Tan, Nicholas McGranahan, Jackie Pierce, Marek Dynowski, Crispin J. Miller, Barbara Mesquita, Dominic G. Rothwell, Cong Zhou, David Allan Moore, Simon P. Pearce, Fabio Gomes, Philip A.J. Crosbie, Jonathan Tugwood, Nicolai Juul Birkbak, R. Shah, Gareth A. Wilson, Christopher Abbosh, Sophia Ward, Maise Al Bakir, Allan Hackshaw, Crispin T. Hiley, Caroline Dive, Dhruva Biswas, Yvonne Summers

Publikováno v: Chemi, F, Rothwell, D G, McGranahan, N, Gulati, S, Abbosh, C, Pearce, S P, Zhou, C, Wilson, G A, Jamal-Hanjani, M, Birkbak, N, Pierce, J, Kim, C S, Ferdous, S, Burt, D J, Slane-Tan, D, Gomes, F, Moore, D, Shah, R, Al Bakir, M, Hiley, C, Veeriah, S, Summers, Y, Crosbie, P, Ward, S, Mesquita, B, Dynowski, M, Biswas, D, Tugwood, J, Blackhall, F, Miller, C, Hackshaw, A, Brady, G, Swanton, C, Dive, C & TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1

Approximately 50% of patients with early-stage non-small-cell lung cancer (NSCLC) who undergo surgery with curative intent will relapse within 5 years1,2. Detection of circulating tumor cells (CTCs) at the time of surgery may represent a tool to iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d6ddd0b6c3e7f59bde65bfbe961685
https://doi.org/10.1038/s41591-019-0593-1