Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marek Cholody"'
Autor:
Barbara A. Woynarowska, Christopher J. Michejda, Anne Monks, Teresa Kosakowska-Cholody, W. Marek Cholody
Publikováno v:
Molecular cancer therapeutics. 4(10)
WMC-79 is a synthetic agent with potent activity against colon and hematopoietic tumors. In vitro, the agent is most potent against colon cancer cells that carry the wild-type p53 tumor suppressor gene (HCT-116 and RKO cells: GI50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2abb88366a2d4902021d4360e06e8c3
https://pubmed.ncbi.nlm.nih.gov/16227412
https://pubmed.ncbi.nlm.nih.gov/16227412
Autor:
Jakub Woyciechowski, Paulina Szczepanska, Angelo Sanzone, Adrian Zarebski, Agnieszka Dreas, Karolina Krawczynska, Ewa Trebacz, Adam Radzimierski, Radosław Obuchowicz, Malgorzata Zurawska, Karolina Osowska, Mariusz Milik, Katarzyna Wiklik, Katarzyna Kucwaj, Krzysztof Brzózka, Marek Cholody, Magdalena Salwińska, Arkadiusz Białas, Joanna Fogt, Renata Windak, Tomasz Rzymski
Publikováno v:
Cancer Research. 73:696-696
CDK8 is a kinase component of the mediator complex which functions as a bridge between a basal transcriptional machinery and specific transcription factors. CDK8 is amplified and differentially expressed in colorectal cancer and in certain hematologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a539223a66775ddbb5387230f8eb3d3d
https://doi.org/10.1158/1538-7445.am2013-696
https://doi.org/10.1158/1538-7445.am2013-696
Autor:
Tomasz Rzymski, Mariusz Milik, Renata Windak, Katarzyna Prymula, Marek Cholody, Adrian Zarebski, Agnieszka Klosowska-Wardega, Zaneta Sibinska, Ewa Trebacz, Krzysztof Brzózka, Nicolas Beuzen, Agnieszka Szamborska-Gbur
Publikováno v:
Cancer Research. 72:3845-3845
The mitotic machinery is a validated target for potential drug therapies in cancer. However, anti-mitotic agents are not without complications from various side effects, notably neurological and hematological toxicities. There is much interest in ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e367417e4ee25d9df884b0cdbd20a9
https://doi.org/10.1158/1538-7445.am2012-3845
https://doi.org/10.1158/1538-7445.am2012-3845
Autor:
Malgorzata Zurawska, Tomasz Rzymski, Piotr Kowalczyk, Marek Cholody, Zaneta Sibinska, Krzysztof Brzózka, Katarzyna Prymula, Nicolas Beuzen, Agnieszka Klosowska-Wardega, Wojciech Czardybon, Monika Guratowska, Renata Windak, Mariusz Milik, Karolina Krawczynska, Aleksandra Sabiniarz, Ewa Trebacz, Agnieszka Szamborska-Gbur
Publikováno v:
Molecular Cancer Therapeutics. 10:A243-A243
The family of Pim kinases emerged as a novel and interesting target with significant potential for therapeutic intervention in cancer. All three members of the family Pim-1, Pim-2 and Pim-3 were shown to be prevent apoptosis, promote protein translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::749417ba801ee652947aed48d153d228
https://doi.org/10.1158/1535-7163.targ-11-a243
https://doi.org/10.1158/1535-7163.targ-11-a243
Autor:
Krzysztof Brzózka, Agnieszka Klosowska-Wardega, Tomasz Rzymski, Ewa Trebacz, Agnieszka Szamborska-Gbur, Zaneta Sibinska, Katarzyna Prymula, Mariusz Milik, Adrian Zarebski, Wojciech Czardybon, Karolina Krawczynska, Marek Cholody, Renata Windak, Nicolas Beuzen
Publikováno v:
Molecular Cancer Therapeutics. 10:B242-B242
The mitotic machinery is a validated target for potential drug therapies in cancer. Anti-mitotic drugs like vinca alkaloids and taxanes interfering with microtubules are important classes of chemotherapeutical agents. However, these agents are not wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008a68259871326283f9ac37ef885a23
https://doi.org/10.1158/1535-7163.targ-11-b242
https://doi.org/10.1158/1535-7163.targ-11-b242
Autor:
Marek Cholody, Ewa Trebacz, Krzysztof Brzózka, Nicolas Beuzen, Wojciech Czardybon, Adrian Zarebski
Publikováno v:
Cancer Research. 70:4499-4499
The Pim serine-threonine kinase family is composed of three members that play an important role in intracellular signaling and contribute to pathways involved in cell survival, proliferation, stress response and cellular motility. Out the three famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3bcd1d800d5294ae5958e2f02fb7e5b
https://doi.org/10.1158/1538-7445.am10-4499
https://doi.org/10.1158/1538-7445.am10-4499