Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marek Adam Harhala"'
Autor:
Natalia Bagińska, Ilona Grygiel, Filip Orwat, Marek Adam Harhala, Adam Jędrusiak, Elżbieta Gębarowska, Sławomir Letkiewicz, Andrzej Górski, Ewa Jończyk-Matysiak
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Acinetobacter baumannii is currently a serious threat to human health, especially to people with immunodeficiency as well as patients with prolonged hospital stays and those undergoing invasive medical procedures. The ever-increasing percent
Externí odkaz:
https://doaj.org/article/d0fa5067df394f11acf7c3cdc998d4ce
Autor:
Marek Adam Harhala, Katarzyna Gembara, Izabela Rybicka, Zuzanna Maria Kaźmierczak, Paulina Miernikiewicz, Joanna Marta Majewska, Wiktoria Budziar, Anna Nasulewicz-Goldeman, Daniel C. Nelson, Barbara Owczarek, Krystyna Dąbrowska
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bacteriolytic enzymes are promising antibacterial agents, but they can cause a typical immune response in vivo. In this study, we used a targeted modification method for two antibacterial endolysins, Pal and Cpl-1. We identified the key immunogenic a
Externí odkaz:
https://doaj.org/article/921cc27f8a7645c29fa84e3ab39311ad
Autor:
Marek Adam Harhala, Katarzyna Gembara, Krzysztof Baniecki, Aleksandra Pikies, Artur Nahorecki, Natalia Jędruchniewicz, Zuzanna Kaźmierczak, Izabela Rybicka, Tomasz Klimek, Wojciech Witkiewicz, Kamil Barczyk, Marlena Kłak, Krystyna Dąbrowska
Publikováno v:
Viruses, Vol 16, Iss 1, p 58 (2023)
Multiple pathogens are competing against the human immune response, leading to outbreaks that are increasingly difficult to control. For example, the SARS-CoV-2 virus continually evolves, giving rise to new variants. The ability to evade the immune s
Externí odkaz:
https://doaj.org/article/91824f60f28b4aeda881ec1d94ece382
Autor:
Paulina Miernikiewicz, Jakub Barylski, Aleksandra Wilczak, Anna Dragoš, Izabela Rybicka, Sophia Bałdysz, Aleksander Szymczak, Iztok Dogsa, Kostiantyn Rokush, Marek Adam Harhala, Jarosław Ciekot, Stanisław Ferenc, Jan Gnus, Wojciech Witkiewicz, Krystyna Dąbrowska
Publikováno v:
Cells, Vol 12, Iss 15, p 1997 (2023)
Rothia is an opportunistic pathogen, particularly life-threatening for the immunocompromised. It is associated with pneumonia, endocarditis, peritonitis and many other serious infections, including septicemia. Of note, Rothia mucilaginousa produces m
Externí odkaz:
https://doaj.org/article/192d392ee01a4bbca5e5eb7bd8d59041
Autor:
Natalia Bagińska, Marek Adam Harhala, Martyna Cieślik, Filip Orwat, Beata Weber-Dąbrowska, Krystyna Dąbrowska, Andrzej Górski, Ewa Jończyk-Matysiak
Publikováno v:
Viruses, Vol 15, Iss 1, p 231 (2023)
Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics. Treatment of infe
Externí odkaz:
https://doaj.org/article/5e7402666dc345978f7989f7b7121104
Autor:
Marek Adam Harhala, Katarzyna Gembara, Daniel C. Nelson, Paulina Miernikiewicz, Krystyna Dąbrowska
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 966 (2022)
Endolysins are bacteriolytic enzymes derived from bacteriophages. They represent an alternative to antibiotics, since they are not susceptible to conventional antimicrobial resistance mechanisms. Since non-human proteins are efficient inducers of spe
Externí odkaz:
https://doaj.org/article/586054e7c5d640f089021ba243987e75