Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marek A. Budzyński"'
Autor:
Alexander J. Baker-Williams, Fiza Hashmi, Marek A. Budzyński, Mark R. Woodford, Stephanie Gleicher, Samu V. Himanen, Alan M. Makedon, Derek Friedman, Stephanie Cortes, Sara Namek, William G. Stetler-Stevenson, Gennady Bratslavsky, Alaji Bah, Mehdi Mollapour, Lea Sistonen, Dimitra Bourboulia
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1894-1906.e6 (2019)
Summary: The extracellular molecular chaperone heat shock protein 90 (eHSP90) stabilizes protease client the matrix metalloproteinase 2 (MMP2), leading to tumor cell invasion. Although co-chaperones are critical modulators of intracellular HSP90:clie
Externí odkaz:
https://doaj.org/article/5c2fb5f7bb824f3faae72044a1736056
Heat shock transcription factors demonstrate a distinct mode of interaction with mitotic chromosomes
Autor:
Rachel M Price, Marek A Budzyński, Junzhou Shen, Jennifer E Mitchell, James Z J Kwan, Sheila S Teves
Publikováno v:
Nucleic Acids Research.
A large number of transcription factors have been shown to bind and interact with mitotic chromosomes, which may promote the efficient reactivation of transcriptional programs following cell division. Although the DNA-binding domain (DBD) contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7dd32a1ad34993716841dc4d65d08ee
https://doi.org/10.1093/nar/gkad304
https://doi.org/10.1093/nar/gkad304
Autor:
Rachel M. Price, Marek A. Budzyński, Junzhou Shen, Jennifer E. Mitchell, James Z.J. Kwan, Sheila S. Teves
A large number of transcription factors have been shown to bind and interact with mitotic chromosomes, which may promote the efficient reactivation of transcriptional programs following cell division. Although the DNA-binding domain (DBD) contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d3b19364bb19ef8663eb6005a1cfd8
https://doi.org/10.1101/2022.10.05.511012
https://doi.org/10.1101/2022.10.05.511012
Autor:
Marek A. Budzyński, Sheila S. Teves
Publikováno v:
Trends in Biochemical Sciences. 47:556-557
Topoisomerase 1 (Top1) relieves torsional stress on DNA, including from RNA Polymerase II (Pol II) transcription. A new study by Wiegard et al. uncovers an unexpected role of Top1 in the appropriate clearance of Pol II from mitotic DNA, allowing for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32cf35c3dec0d00223d66ae36b21933
https://doi.org/10.1016/j.tibs.2022.03.005
https://doi.org/10.1016/j.tibs.2022.03.005
Autor:
Toshiki Kijima, Thomas L. Prince, Megan L. Tigue, Kendrick H. Yim, Harvey Schwartz, Kristin Beebe, Sunmin Lee, Marek A. Budzynski, Heinric Williams, Jane B. Trepel, Lea Sistonen, Stuart Calderwood, Len Neckers
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Heat shock factor 1 (HSF1) initiates a broad transcriptional response to proteotoxic stress while also mediating a cancer-specific transcriptional program. HSF1 is thought to be regulated by molecular chaperones, including Heat Shock Protein
Externí odkaz:
https://doaj.org/article/b5b85ac651e04db4890864d6af7a27c5