Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mareike Pendzialek"'
Publikováno v:
Porcine Health Management, Vol 6, Iss 1, Pp 1-11 (2020)
Abstract Background Streptococcus (S.) suis is a major porcine pathogen causing high morbidity worldwide. This includes well-managed herds with high hygiene standards. In Europe, no licensed vaccine is available. As practitioners are obliged to reduc
Externí odkaz:
https://doaj.org/article/1736df055e3647b29d9a27eb8679dce2
Autor:
Mareike Pendzialek, Tom Seeling, Anne Navarrete Santos, Gerd Nuernberg, Dirk Dannenberger, Maria Schindler, Katarzyna J. Grybel
Publikováno v:
Molecular Human Reproduction
During the first days of development the preimplantation embryo is supplied with nutrients from the surrounding milieu. Maternal diabetes mellitus affects the uterine microenvironment, leading to a metabolic adaptation processes in the embryo. We ana
Autor:
Jacqueline Gürke, Maria Schindler, Elisa Haucke, Katarzyna J. Grybel, Anne Navarrete Santos, Tom Seeling, S. Mareike Pendzialek, Andreas Simm, Alexander Navarrete Santos
Publikováno v:
Reproduction in Domestic Animals. 54:4-11
In a diabetic pregnancy, an altered maternal metabolism led to increased formation of reactive α-dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) in the reproductive organs and embryos. The enzyme glyoxalase (GLO) 1 detoxifies reactive α-di
Autor:
Bernd Fischer, Elen Gocza, Katarzyna J. Grybel, Anne Navarrete Santos, Jacqueline Gürke, Julia M. Knelangen, Maria Schindler, S. Mareike Pendzialek
Publikováno v:
Molecular and Cellular Endocrinology. 480:167-179
MicroRNAs are promising biological markers for prenatal diagnosis. They regulate placental development and are present in maternal plasma. Maternal metabolic diseases are major risk factors for placental deterioration. We analysed the influence of a
Publikováno v:
Porcine Health Management
Background Streptococcus (S.) suis is a major porcine pathogen causing high morbidity worldwide. This includes well-managed herds with high hygiene standards. In Europe, no licensed vaccine is available. As practitioners are obliged to reduce the use
Autor:
Maria Schindler, Sophia Mareike Pendzialek, Katarzyna Grybel, Tom Seeling, Anne Navarrete Santos
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 919 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3, p 919 (2020)
Metabolic disorders of the mother adversely affect early embryo development, causing changes in maternal metabolism and consequent alterations in the embryo environment in the uterus. The goal of this study was to analyse the biochemical profiles of
Autor:
Maria Schindler, Regine Heller, Jacqueline Gürke, Katrin Spengler, Tom P. Fleming, Bernd Fischer, S. Mareike Pendzialek, Anne Navarrete Santos, Katarzyna J. Grybel, René Thieme
Publikováno v:
REPRODUCTION. 151:465-476
The mammalian target of rapamycin complex 1 (mTORC1) is known to be a central cellular nutrient sensor and master regulator of protein metabolism; therefore, it is indispensable for normal embryonic development. We showed previously in a diabetic pre
Autor:
Bernd, Fischer, Maria, Schindler, S, Mareike Pendzialek, Jacqueline, Gürke, Elisa, Haucke, Katarzyna Joanna, Grybel, René, Thieme, Anne Navarrete, Santos
Publikováno v:
Advances in experimental medicine and biology. 1014
Maternal metabolic diseases such as diabetes mellitus with diabetogenic hypoinsulinemia and hyperglycemia change periconceptional developmental conditions in utero. In preimplantation rabbit embryos, all major metabolic pathways are affected. Alterat
Autor:
Elisa Haucke, Katarzyna J. Grybel, S. Mareike Pendzialek, Maria Schindler, Jacqueline Gürke, Anne Navarrete Santos, René Thieme, Bernd Fischer
Publikováno v:
Periconception in Physiology and Medicine ISBN: 9783319624129
Maternal metabolic diseases such as diabetes mellitus with diabetogenic hypoinsulinemia and hyperglycemia change periconceptional developmental conditions in utero. In preimplantation rabbit embryos, all major metabolic pathways are affected. Alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a97b310127fc1a910556876f5ad84167
https://doi.org/10.1007/978-3-319-62414-3_6
https://doi.org/10.1007/978-3-319-62414-3_6
Maternal Diabetes Leads to Unphysiological High Lipid Accumulation in Rabbit Preimplantation Embryos
Autor:
Alexander Navarrete Santos, Maria Schindler, Anne Navarrete Santos, Stefanie Seyring, Torsten Plösch, Bernd Fischer, Elisa Haucke, Mareike Pendzialek, Jacqueline Gürke, Julia M. Knelangen
Publikováno v:
Endocrinology, 155(4), 1498-1509. ENDOCRINE SOC
According to the “developmental origin of health and disease” hypothesis, the metabolic set points of glucose and lipid metabolism are determined prenatally. In the case of a diabetic pregnancy, the embryo is exposed to higher glucose and lipid c