Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Mareike Florek"'
Autor:
Yuqiong Pan, Dennis B. Leveson-Gower, Patricia E. de Almeida, Antonio Pierini, Jeanette Baker, Mareike Florek, Hidekazu Nishikii, Byung-Su Kim, Rong Ke, Joseph C. Wu, Robert S. Negrin
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1793-1802 (2015)
Embryonic stem cells (ESCs) hold promise for the treatment of many medical conditions; however, their utility is limited by immune rejection. The objective of our study is to establish tolerance or promote engraftment of transplanted ESCs as well as
Externí odkaz:
https://doaj.org/article/e334f832edb34799adb0da200b0b04dd
Autor:
Mareike Florek, Dominik Schneidawind, Antonio Pierini, Jeanette Baker, Randall Armstrong, Yuqiong Pan, Dennis Leveson-Gower, Robert Negrin, Everett Meyer
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145763 (2015)
The adoptive transfer of CD4+CD25+Foxp3+ regulatory T cells (Tregs) in murine models of allogeneic hematopoietic cell transplantation (HCT) has been shown to protect recipient mice from lethal acute graft-versus-host disease (GVHD) and this approach
Externí odkaz:
https://doaj.org/article/0494293a86734c18912e497446202cb7
Autor:
Emanuela I Sega, Dennis B Leveson-Gower, Mareike Florek, Dominik Schneidawind, Richard H Luong, Robert S Negrin
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86551 (2014)
Lag-3 has emerged as an important molecule in T cell biology. We investigated the role of Lag-3 in conventional T cell (Tcon) and regulatory T cell (Treg) function in murine GVHD with the hypothesis that Lag-3 engagement diminishes alloreactive T cel
Externí odkaz:
https://doaj.org/article/a0faece07ceb4400b242bf8d6059b24b
Autor:
Dullei Min, Robert B. Levy, Gerlinde Wernig, Mareike Florek, Judith A. Shizuru, Victor L. Perez, Samantha Herretes, Casey Burnett, Antonia M.S. Müller, Kenneth Weinberg
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 25(12)
Graft-versus-host disease (GVHD) remains a major complication of allogeneic hematopoietic cell transplantation. Acute GVHD (aGVHD) results from direct damage by donor T cells, whereas the biology of chronic GVHD (cGVHD) with its autoimmune-like manif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae51926c670ee1613f4af2e1cdbc72c
https://pubmed.ncbi.nlm.nih.gov/31415899
https://pubmed.ncbi.nlm.nih.gov/31415899
Autor:
Hidekazu Nishikii, Byung Su Kim, Maite Alvarez, Yuqiong Pan, Antonio Pierini, Dominik Schneidawind, Jeanette Baker, Lucrezia Colonna, Robert S. Negrin, Mareike Florek
Publikováno v:
The Journal of Immunology. 195:347-355
Adoptive transfer of freshly isolated natural occurring CD4+CD25+Foxp3+ regulatory T cells (Treg) prevents graft-versus-host disease (GVHD) in several animal models and following hematopoietic cell transplantation (HCT) in clinical trials. Donor-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f7249e94b73a8ca2d643747a6d7bba
https://doi.org/10.4049/jimmunol.1402861
https://doi.org/10.4049/jimmunol.1402861
Autor:
Jeanette Baker, Antonio Pierini, Yuqiong Pan, Dennis B. Leveson-Gower, Robert S. Negrin, Mareike Florek, Hidekazu Nishikii, Patrícia de Almeida, Joseph C. Wu, Byung-Su Kim, Rong Ke
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1793-1802 (2015)
Summary Embryonic stem cells (ESCs) hold promise for the treatment of many medical conditions; however, their utility is limited by immune rejection. The objective of our study is to establish tolerance or promote engraftment of transplanted ESCs as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9ff56990bf470f99fe8c8d7dd10f7b
https://doi.org/10.1016/j.celrep.2015.02.050
https://doi.org/10.1016/j.celrep.2015.02.050
Autor:
David Ritchie, Saar Gill, Aaron Smith, Jeanette Baker, Alysha De Souza, Robert S. Negrin, Mareike Florek, Adrianne E Vasey, Keri Tate, Holbrook E Kohrt, Kenneth D. Gibbs
Publikováno v:
Blood. 119:5758-5768
Natural killer (NK) cells are potent anti-viral and antitumor “first responders” endowed with natural cytotoxicity and cytokine production capabilities. To date, attempts to translate these promising biologic functions through the adoptive transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf0d06dbe818639f32c2caa62dd72dd
https://doi.org/10.1182/blood-2012-03-415364
https://doi.org/10.1182/blood-2012-03-415364
Autor:
Robert S. Negrin, Robert Lowsky, David B. Miklos, Laura Johnston, Sally Arai, Mareike Florek, Judith A. Shizuru, Janice M. Brown, Philip W. Lavori, K Sheehan, J S McCune, Randall Armstrong, Ginna G. Laport
Publikováno v:
Bone marrow transplantation
We investigated sirolimus and mycophenolate mofetil (MMF) as GVHD prophylaxis in patients with advanced hematological malignancies receiving myeloablative hematopoietic cell transplantation (HCT) from HLA-identical sibling donors. On the basis of pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f1bef40cf543aaac7a8a8adec74c24
https://doi.org/10.1038/bmt.2011.104
https://doi.org/10.1038/bmt.2011.104
Autor:
Antonia M.S. Müller, Mareike Florek, Jessica A. Linderman, Judith A. Shizuru, David B. Miklos
Publikováno v:
Proceedings of the National Academy of Sciences. 107:14721-14726
Because of the perception that depleting hematopoietic grafts of T cells will result in poorer immune recovery and in increased risk of graft rejection, pure hematopoietic stem cells (HSC), which avoid the potentially lethal complication of graft-ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04a2212a0e756dc2ca0dd9ac0d2a5bd
https://doi.org/10.1073/pnas.1009220107
https://doi.org/10.1073/pnas.1009220107
Autor:
Martin Bornhäuser, Mareike Florek, Nicola Bauer, Ana-Violeta Fonseca, Daniel Freund, Christine A. Fargeas, Denis Corbeil, József Jászai
Publikováno v:
Cells Tissues Organs 2008;188:127–138, ISSN: 1422-6405
Prominin-1 (alias CD133) has received considerable interest because of its expression by several stem and progenitor cells originating from various sources, including the neural and hematopoietic systems. As a cell surface marker, prominin-1 is now u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fd6e457e46c89abcc04fcbdf95c109
https://doi.org/10.1159/000112847
https://doi.org/10.1159/000112847