Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mardi Fink"'
Autor:
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I. Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Constantinos Koumenis, Andy J. Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Ionizing radiation induces cell death in the gastrointestinal (GI) epithelium by activating p53. However, p53 also prevents animal lethality caused by radiation-induced acute GI syndrome. Through single-cell RNA-sequencing of the irradiated
Externí odkaz:
https://doaj.org/article/f8259dde53cf4c8bad036795c5ff982c
Autor:
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Costas Koumenis, Andy J Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch
Publikováno v:
bioRxiv
Ionizing radiation induces cell death in the gastrointestinal (GI) epithelium by activating p53. However, p53 also prevents animal lethality caused by radiation-induced GI injury. Through single-cell RNA-sequencing of the irradiated mouse intestine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36630c4c6812ec55c808e0065a530c5b
https://doi.org/10.1101/2023.04.27.538576
https://doi.org/10.1101/2023.04.27.538576
Autor:
Jeff Wrana, Mardi Fink
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES.
The delicate balance between the homeostatic maintenance and regenerative capacity of the intestine makes this a fascinating tissue of study. The intestinal epithelium undergoes continuous homeostatic renewal but is also exposed to a diverse array of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0279a16f6df6ddd5c4cb3585e652170f
https://pubmed.ncbi.nlm.nih.gov/35611490
https://pubmed.ncbi.nlm.nih.gov/35611490
Autor:
Jess Shen, Seda Barutcu, Jeffrey L. Wrana, Shaida Ouladan, Mardi Fink, Arshad Ayyaz, Bibaswan Ghoshal, Bruno Sangiorgi, Sandeep Kumar, Jessica Gosio, Daniel Trcka, Kin Chan, Alex Gregorieff
Publikováno v:
Nature. 569:121-125
The turnover of the intestinal epithelium is driven by multipotent LGR5+ crypt-base columnar cells (CBCs) located at the bottom of crypt zones1. However, CBCs are lost following injury, such as irradiation2, but the intestinal epithelium is neverthel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad608824a4a87893c5442fc575d50ca6
https://doi.org/10.1038/s41586-019-1154-y
https://doi.org/10.1038/s41586-019-1154-y
Autor:
Han, Chang1 (AUTHOR) chang.han@majorbio.com, Shi, Caiping1 (AUTHOR), Liu, Linmeng1 (AUTHOR), Han, Jichen1 (AUTHOR) jichen.han@majorbio.com, Yang, Qianqian1 (AUTHOR), Wang, Yan1 (AUTHOR), Li, Xiaodan1 (AUTHOR), Fu, Wenyao1 (AUTHOR), Gao, Hao1 (AUTHOR), Huang, Huasheng1 (AUTHOR), Zhang, Xianglin1 (AUTHOR), Yu, Kegang1 (AUTHOR)
Publikováno v:
iMeta. Aug2024, Vol. 3 Issue 4, p1-6. 6p.
Autor:
Bourmoum, Mohamed1 (AUTHOR), Radulovich, Nikolina2 (AUTHOR), Sharma, Amit1 (AUTHOR), Tkach, Johnny M.1 (AUTHOR), Tsao, Ming-Sound2 (AUTHOR), Pelletier, Laurence1,3 (AUTHOR) pelletier@lunenfeld.ca
Publikováno v:
PLoS ONE. 2/7/2024, Vol. 19 Issue 2, p1-16. 16p.
Autor:
Morral, Clara, Ayyaz, Arshad, Kuo, Hsuan-Cheng, Fink, Mardi, Verginadis, Ioannis I., Daniel, Andrea R., Burner, Danielle N., Driver, Lucy M., Satow, Sloane, Hasapis, Stephanie, Ghinnagow, Reem, Luo, Lixia, Ma, Yan, Attardi, Laura D., Koumenis, Constantinos, Minn, Andy J., Wrana, Jeffrey L., Lee, Chang-Lung, Kirsch, David G.
Publikováno v:
Nature Communications; 4/22/2024, Vol. 15 Issue 1, p1-14, 14p
Autor:
Fink, Mardi, Wrana, Jeffrey L.
Publikováno v:
Developmental Dynamics; Apr2023, Vol. 252 Issue 4, p445-462, 18p
Autor:
Ayyaz, Arshad, Kumar, Sandeep, Sangiorgi, Bruno, Ghoshal, Bibaswan, Gosio, Jessica, Ouladan, Shaida, Fink, Mardi, Barutcu, Seda, Trcka, Daniel, Shen, Jess, Chan, Kin, Wrana, Jeffrey L., Gregorieff, Alex
Publikováno v:
Nature; 5/2/2019, Vol. 569 Issue 7754, p121-125, 5p, 10 Diagrams, 4 Graphs