Výsledky vyhledávání - "Marder Karen"

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Robust and efficient estimation in the presence of a randomly censored covariate

Autor: Lee, Seong-ho, Richardson, Brian D., Ma, Yanyuan, Marder, Karen S., Garcia, Tanya P.

In Huntington's disease research, a current goal is to understand how symptoms change prior to a clinical diagnosis. Statistically, this entails modeling symptom severity as a function of the covariate 'time until diagnosis', which is often heavily r

Externí odkaz: http://arxiv.org/abs/2409.07795

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Establishing the Parallels and Differences Between Right-Censored and Missing Covariates

Autor: Vazquez, Jesus E., Ashner, Marissa C., Ma, Yanyuan, Marder, Karen, Garcia, Tanya P.

While right-censored time-to-event outcomes have been studied for decades, handling time-to-event covariates, also known as right-censored covariates, is now of growing interest. So far, the literature has treated right-censored covariates as distinc

Externí odkaz: http://arxiv.org/abs/2409.04684

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Akademický článek

Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study

Autor: Guttman, Mark, Raymond, Lynn, Mendis, Tilak, Suchowersky, Oksana, Corey-Bloom, Jody, Geschwind, Michael D, Marshall, Frederick J, Marder, Karen S, Nance, Martha, Racette, Brad, Bang, Jee, Segro, Victoria, McDonell, Katherine, Kamholz, John, LeDoux, Mark S, Sanchez-Ramos, Juan, DeMichele, Giuseppe, Mariotti, Caterina, Squitieri, Ferdinando, Soliveri, Paola, Cortelli, Pietro, Muñoz García, José Esteban, Kulisevsky Bojarski, Jaime, López-Sendón Moreno, José Luis, Berganzo Corrales, Koldo, Cubo, Esther, García Moreno, José Manuel, Orth, Michael, Priller, Josef, Saft, Carsten, Weindl, Adolf, Winkler, Juergen, Craufurd, David, Miedzybrodzka, Zofia, Rickards, Hugh, Davies, Rhys Richard, Lahiri, Nayana, Ruddy, Deborah, Komati, Suresh K, Quarrell, Oliver William John, Correira Guedes, Leonor, Roos, Raymund A C, Zalyalova, Zuleykha, Illarioshkin, Sergey, Gustov, Aleksandr, Klempir, Jiri, Reilmann, Ralf ^*, Anderson, Karen E, Feigin, Andrew, Tabrizi, Sarah J, Leavitt, Blair R, Stout, Julie C, Piccini, Paola, Schubert, Robin, Loupe, Pippa, Wickenberg, Anna ^*, Borowsky, Beth ^*, Rynkowski, Gail, Volkinshtein, Rita, Li, Thomas, Savola, Juha-Matti ^*, Hayden, Michael ^*, Gordon, Mark Forrest

Publikováno v: In The Lancet Neurology March 2024 23(3):243-255

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Akademický článek

Genome-Wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population

Autor: Liu Xinmin, Cheng Rong, Verbitsky Miguel, Kisselev Sergey, Browne Andrew, Mejia-Sanatana Helen, Louis Elan D, Cote Lucien J, Andrews Howard, Waters Cheryl, Ford Blair, Frucht Steven, Fahn Stanley, Marder Karen, Clark Lorraine N, Lee Joseph H

Publikováno v: BMC Medical Genetics, Vol 12, Iss 1, p 104 (2011)

Abstract Background To date, nine Parkinson disease (PD) genome-wide association studies in North American, European and Asian populations have been published. The majority of studies have confirmed the association of the previously identified geneti

Externí odkaz: https://doaj.org/article/b5acfc1b9d3b4aceb630101c02ca45c6

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Akademický článek

Genome-wide significance for a modifier of age at neurological onset in Huntington's Disease at 6q23-24: the HD MAPS study

Publikováno v: BMC Medical Genetics, Vol 7, Iss 1, p 71 (2006)

Abstract Background Age at onset of Huntington's disease (HD) is correlated with the size of the abnormal CAG repeat expansion in the HD gene; however, several studies have indicated that other genetic factors also contribute to the variability in HD

Externí odkaz: https://doaj.org/article/e3f085610415408f8f263d3a98bea8fe

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