Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Mardaryev, Andrei"'
Autor:
Chen, G-D., Fatima, I., Xu, Q, Rozhkova, E., Fessing, Michael Y., Mardaryev, Andrei N., Sharov, A.A., Xu, G-L., Botchkarev, Vladimir A.
Yes
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre
Externí odkaz:
http://hdl.handle.net/10454/19330
Spatial genome organization in the cell nucleus plays a crucial role in the control of genome functions. Our knowledge about spatial genome organization is relying on the advances in gene imaging technologies and the biochemical approaches based on t
Externí odkaz:
http://hdl.handle.net/10454/18511
Autor:
Buscone, S., Mardaryev, Andrei N., Raafs, B., Bikker, J.W., Sticht, C., Gretz, N., Farjo, N.P., Uzunbajakava, N.E., Botchkareva, Natalia V.
Yes
Background and Objective: Though devices for hair growth based on low levels of light have shown encouraging results, further improvements of their efficacy is impeded by a lack of knowledge on the exact molecular targets that mediate physio
Background and Objective: Though devices for hair growth based on low levels of light have shown encouraging results, further improvements of their efficacy is impeded by a lack of knowledge on the exact molecular targets that mediate physio
Externí odkaz:
http://hdl.handle.net/10454/12062
Autor:
Rapisarda, Valentina, Malashchuk, Igor, Asamaowei, Inemo E., Poterlowicz, Krzysztof, Fessing, Michael Y., Sharov, A.A., Karakesisoglou, I., Botchkarev, Vladimir A., Mardaryev, Andrei N.
Yes
The maintenance of a proper nuclear architecture and 3D organization of the genes, enhancer elements and transcription machinery plays an essential role in tissue development and regeneration. Here we show that in the developing skin, epider
The maintenance of a proper nuclear architecture and 3D organization of the genes, enhancer elements and transcription machinery plays an essential role in tissue development and regeneration. Here we show that in the developing skin, epider
Externí odkaz:
http://hdl.handle.net/10454/12280
Autor:
Poterlowicz, Krzysztof, Yarker, Joanne L., Malashchuk, Igor, Lajoie, B.R., Mardaryev, Andrei N., Gdula, M.R., Sharov, A.A., Kohwi-Shigematsu, T., Botchkarev, Vladimir A., Fessing, Michael Y.
Yes
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologi
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologi
Externí odkaz:
http://hdl.handle.net/10454/17918
Autor:
Aunin, Eerik, Broadley, David, Ahmed, Mohammed I., Mardaryev, Andrei N., Botchkareva, Natalia V.
Yes
Multiple factors and conditions can lead to impaired wound healing. Chronic non-healing wounds are a common problem among the elderly. To identify microRNAs negatively impacting the wound repair, global miRNA profiling of wounds collected fr
Multiple factors and conditions can lead to impaired wound healing. Chronic non-healing wounds are a common problem among the elderly. To identify microRNAs negatively impacting the wound repair, global miRNA profiling of wounds collected fr
Externí odkaz:
http://hdl.handle.net/10454/12063
Autor:
Mardaryev, Andrei N., Liu, B., Rapisarda, Valentina, Poterlowicz, Krzysztof, Malashchuk, Igor, Rudolf, Jana, Sharov, A.A., Jahoda, C.J., Fessing, Michael Y., Benitah, S., Xu, G., Botchkarev, Vladimir A.
Yes
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a criti
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a criti
Externí odkaz:
http://hdl.handle.net/10454/10161
Bone morphogenetic proteins (BMPs) and their receptors (BMPRs) play roles in embryonic development and postnatal remodelling of the skin. Many indications suggest that BMP signalling regulates keratinocyte proliferation and differentiation. Chronic w
Externí odkaz:
http://hdl.handle.net/10454/9371
Autor:
Lewis, Christopher J., Mardaryev, Andrei N., Sharov, A.A., Fessing, Michael Y., Botchkarev, Vladimir A.
Significance: Epigenetic regulatory mechanisms are essential for epidermal homeostasis and contribute to the pathogenesis of many skin diseases, including skin cancer and psoriasis. However, while the epigenetic regulation of epidermal homeostasis is
Externí odkaz:
http://hdl.handle.net/10454/6830