Výsledky vyhledávání - "Marcus W. Noetzel"

Design of HIV-1 Protease Inhibitors with Pyrrolidinones and Oxazolidinones as Novel P1′-Ligands To Enhance Backbone-Binding Interactions with Protease: Synthesis, Biological Evaluation, and Protein−Ligand X-ray Studies

Autor: Yunfeng Tie, Hiroaki Mitsuya, Abigail Baldridge, Irene T. Weber, Marcus W. Noetzel, Yuan-Fang Wang, Heather B. Miller, Sofiya Leshchenko-Yashchuk, David D. Anderson, Arun K. Ghosh, Yasuhiro Koh

Publikováno v: Journal of Medicinal Chemistry. 52:3902-3914

Structure-based design, synthesis, and biological evaluation of a series of novel HIV-1 protease inhibitors are described. In an effort to enhance interactions with protease backbone atoms, we have incorporated stereochemically defined methyl-2-pyrro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388757a081d5ed02e2bd0f7821006170
https://doi.org/10.1021/jm900303m

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ChemInform Abstract: Cyclopropyl Building Blocks in Organic Synthesis. Part 66. A New and Efficient Access to Thiazoline-4-carboxylates and Cysteine Derivatives Incorporating Cyclopropyl Groups

Autor: Thomas Labahn, Mazen Es‐Sayed, Marcus W. Noetzel, Armin de Meijere

Publikováno v: ChemInform. 33

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2db7b5d200bf53e4ce6b030be0ad9d5b
https://doi.org/10.1002/chin.200213134

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ChemInform Abstract: Cyclopropyl Building Blocks for Organic Synthesis. Part 75. Domino Reactions of Amidines with Methyl 2-Chloro-2-cyclopropylideneacetates as an Efficient Access to Cyclobutene-Anellated Pyrimidinones

Autor: Armin de Meijere, Marcus W. Noetzel, Thomas Labahn, Karsten Rauch

Publikováno v: ChemInform. 33

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f620ed041aa8278d39f03d845a3d423c
https://doi.org/10.1002/chin.200234168

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ChemInform Abstract: Cyclopropyl Building Blocks in Organic Synthesis. Part 151. Diastereoselective Synthesis of Alkylcyclopropane-Anellated Methyl 2-Iminoimidazolinecarboxylates

Autor: Thomas Labahn, Joerg Magull, Marcus W. Noetzel, Armin de Meijere, Daniel Frank

Publikováno v: ChemInform. 40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1cab2d467c4e2077a57b8db45531902
https://doi.org/10.1002/chin.200932124

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ChemInform Abstract: Cyclopropyl Building Blocks for Organic Synthesis. Part 148. A Convenient Access to Variously Substituted Spiro[cyclopropane-1,4′-oxazoline]s

Autor: Marcus W. Noetzel, Mazen Es‐Sayed, Armin de Meijere, Suryakanta Dalai

Publikováno v: ChemInform. 39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c3f083930571f7a74532be9664afd79
https://doi.org/10.1002/chin.200846121

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Synthesis and Bioactivities of Paclitaxel Analogues with a Cyclopropanated Side-Chain

Autor: Markus Tamm, Armin de Meijere, Marcus W. Noetzel, Jennifer K. Schilling, David G. I. Kingston, Changhui Liu

Publikováno v: ChemInform. 34

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71577abfe31d28b3373ac41c84108bfd
https://doi.org/10.1002/chin.200322195

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ChemInform Abstract: Cyclopropyl Building blocks in Organic Synthesis. Part 56. A New and Efficient Access to Oxazoline-5-carboxylates and Amino Acid Derivatives with Cyclopropyl Groups

Autor: Markus Tamm, Thomas Labahn, Mazen Es‐Sayed, Marcus W. Noetzel, Mathias Noltemeyer, Armin de Meijere

Publikováno v: ChemInform. 31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b40c52447b96109992a7cb799775ff8
https://doi.org/10.1002/chin.200043143

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