Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marcus V. Ortega Alves"'
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Assessment of the degree of synergy between cisplatin and MK-1775 in HN30 (wild-type TP53) and HN31 (mutant TP53) HNSCC cells respectively using the Chou and Talalay method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6352838fedef24046c6d1458ef5d2e
https://doi.org/10.1158/1535-7163.22503727.v1
https://doi.org/10.1158/1535-7163.22503727.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Dual phospho-H3 staining for mitotic cells and PI flow cytometric analysis (FACS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927d055bc5672add4446b73b22f7cfce
https://doi.org/10.1158/1535-7163.22503724.v1
https://doi.org/10.1158/1535-7163.22503724.v1
PDF file - 132K, Differentially expressed genes between resistant/bevacizumab tumors compared to parental/bevacizumab tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396f0375a360d4dd8dd26a69d03b2697
https://doi.org/10.1158/1541-7786.22509913.v1
https://doi.org/10.1158/1541-7786.22509913.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Figures PDF - file 648K, This file contains supplementary figures S1-S5. Figure S1 has additional copy number analysis. Figure S2 expands on the integration of gene expression and copy number analysis. Figures S3-S4 provide additional d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15405d8619b8a7073c811fb586348df3
https://doi.org/10.1158/2159-8290.22530170.v1
https://doi.org/10.1158/2159-8290.22530170.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Tables -XLSX file 2328K, This file contains supplemental tables S1-S14. These tables describe the clinical, pathological and genomic information for this study. Also included are GISTIC peak information, expression and copy number corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea24a3d1cce25ad579996d2700b9847
https://doi.org/10.1158/2159-8290.22530167
https://doi.org/10.1158/2159-8290.22530167
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Determination of drug synergy by the combination-index and isobologram analyses using the CalcuSyn software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b6583d3f2e7dbca8d53f20c5eca8
https://doi.org/10.1158/1535-7163.22503718.v1
https://doi.org/10.1158/1535-7163.22503718.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
The survival of patients with oral squamous cell carcinoma (OSCC) has not changed significantly in several decades, leading clinicians and investigators to search for promising molecular targets. To this end, we conducted comprehensive genomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0124def50b57b5023ab4f2e11dc99bd
https://doi.org/10.1158/2159-8290.c.6546119.v1
https://doi.org/10.1158/2159-8290.c.6546119.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
The Wee-1 inhibitor, MK-1775 Synergizes with cisplatin in vitro in established HNSCC cell lines with known TP53 mutational status; Dual phospho-H3 staining and PI flow cytometric analysis (FACS); The synergy between cisplatin and MK-1775 in HNSCC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872ee87af6f3bd14707abe7cf9ba62ff
https://doi.org/10.1158/1535-7163.22503730
https://doi.org/10.1158/1535-7163.22503730
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Text - PDF file 435K, This file contains supplementary methods, figure legends for supplementary figures S1-S5, descriptions for supplementary tables S1-S14, legends for supplementary methods figures SM1-SM15, supplementary references 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b27d545d9a9feefc812f79734ae912b
https://doi.org/10.1158/2159-8290.22530164
https://doi.org/10.1158/2159-8290.22530164
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
The underlying synergy between cisplatin and MK-1775 in HNSCC is not mediated by apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486b8f8200d5ff59379bb1060e1bb04c
https://doi.org/10.1158/1535-7163.22503721.v1
https://doi.org/10.1158/1535-7163.22503721.v1