Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Marcus V, Ortega"'
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Assessment of the degree of synergy between cisplatin and MK-1775 in HN30 (wild-type TP53) and HN31 (mutant TP53) HNSCC cells respectively using the Chou and Talalay method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6352838fedef24046c6d1458ef5d2e
https://doi.org/10.1158/1535-7163.22503727.v1
https://doi.org/10.1158/1535-7163.22503727.v1
PDF file - 132K, Differentially expressed genes between resistant/bevacizumab tumors compared to parental/bevacizumab tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396f0375a360d4dd8dd26a69d03b2697
https://doi.org/10.1158/1541-7786.22509913.v1
https://doi.org/10.1158/1541-7786.22509913.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Figures PDF - file 648K, This file contains supplementary figures S1-S5. Figure S1 has additional copy number analysis. Figure S2 expands on the integration of gene expression and copy number analysis. Figures S3-S4 provide additional d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15405d8619b8a7073c811fb586348df3
https://doi.org/10.1158/2159-8290.22530170.v1
https://doi.org/10.1158/2159-8290.22530170.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Tables -XLSX file 2328K, This file contains supplemental tables S1-S14. These tables describe the clinical, pathological and genomic information for this study. Also included are GISTIC peak information, expression and copy number corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea24a3d1cce25ad579996d2700b9847
https://doi.org/10.1158/2159-8290.22530167
https://doi.org/10.1158/2159-8290.22530167
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
Determination of drug synergy by the combination-index and isobologram analyses using the CalcuSyn software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b6583d3f2e7dbca8d53f20c5eca8
https://doi.org/10.1158/1535-7163.22503718.v1
https://doi.org/10.1158/1535-7163.22503718.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
The survival of patients with oral squamous cell carcinoma (OSCC) has not changed significantly in several decades, leading clinicians and investigators to search for promising molecular targets. To this end, we conducted comprehensive genomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0124def50b57b5023ab4f2e11dc99bd
https://doi.org/10.1158/2159-8290.c.6546119.v1
https://doi.org/10.1158/2159-8290.c.6546119.v1
Autor:
Jeffrey N. Myers, Olivier Lichtarge, Raymond E. Meyn, Marek Kimmel, Thomas O. McDonald, Teng-Kuei Hsu, Carlos Caulin, Sang Hyeok Woo, Mitchell J. Frederick, David M. Neskey, Alison L. Fitzgerald, Panagiotis Katsonis, Ameeta A. Patel, Marcus V. Ortega Alves, Marcus M. Monroe, Abdullah A. Osman
The Wee-1 inhibitor, MK-1775 Synergizes with cisplatin in vitro in established HNSCC cell lines with known TP53 mutational status; Dual phospho-H3 staining and PI flow cytometric analysis (FACS); The synergy between cisplatin and MK-1775 in HNSCC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872ee87af6f3bd14707abe7cf9ba62ff
https://doi.org/10.1158/1535-7163.22503730
https://doi.org/10.1158/1535-7163.22503730
Autor:
Jeffrey N. Myers, Mitchell J. Frederick, Jing Wang, David A. Wheeler, John N. Weinstein, Richard Gibbs, Adel K. El-Naggar, Jennifer Drummond, Jane H. Zhou, Marcus V. Ortega Alves, C. Jillian Tsai, Alexandra Ward, Jiping Wang, Samar A. Jasser, Mei Zhao, David M. Neskey, Jiexin Zhang, Curtis R. Pickering
Supplementary Figure S1. Association between age, number of mutations and smoking status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0415ba4892103c93cca85ac80aa2bf34
https://doi.org/10.1158/1078-0432.22455279.v1
https://doi.org/10.1158/1078-0432.22455279.v1
Autor:
Jeffrey N. Myers, Mitchell J. Frederick, Jing Wang, David A. Wheeler, John N. Weinstein, Richard Gibbs, Adel K. El-Naggar, Jennifer Drummond, Jane H. Zhou, Marcus V. Ortega Alves, C. Jillian Tsai, Alexandra Ward, Jiping Wang, Samar A. Jasser, Mei Zhao, David M. Neskey, Jiexin Zhang, Curtis R. Pickering
Purpose: Epidemiologic studies have identified an increasing incidence of squamous cell carcinoma of the oral tongue (SCCOT) in younger patients.Experimental Design: DNA isolated from tongue tumors of young (45 years) patients at was subjected to who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4e34e833e7379bc8873f75258c292a
https://doi.org/10.1158/1078-0432.c.6522975.v1
https://doi.org/10.1158/1078-0432.c.6522975.v1
Autor:
Marcus V. Ortega, Marcela G. del Carmen, May Wakamatsu, Susan A. Goldstein, Eirian Siegal-Botti, Jason H. Wasfy
Publikováno v:
Menopause. 29:723-727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cea910c8b59a92e980f8a773f11fb7b
https://doi.org/10.1097/gme.0000000000001957
https://doi.org/10.1097/gme.0000000000001957
