Zobrazeno 1 - 10
of 361
pro vyhledávání: '"Marcus Tullius Scotti"'
Autor:
Bruna Ramos dos Santos, Amanda Bruno da Silva Bellini Ramos, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fábio Antônio Colombo, Marcos José Marques, Juliana Quero Reimão
Publikováno v:
Parasitology, Vol 150, Pp 1226-1235 (2023)
Toxoplasmosis is a significant public health concern with limited therapeutic options. The medicines for malaria venture (MMV) developed the pandemic response box (PRB) containing 400 drug-like molecules with broad pathogen activity. The aim of this
Externí odkaz:
https://doaj.org/article/8423dd6b586340a1a09d6bd59638407d
Autor:
Rafael Bello Gonçalves, Witor Ribeiro Ferraz, Raisa Ludmila Calil, Marcus Tullius Scotti, Gustavo Henrique Goulart Trossini
Publikováno v:
ACS Omega, Vol 8, Iss 42, Pp 38961-38982 (2023)
Externí odkaz:
https://doaj.org/article/c1729b4f665140248384d39fce551702
Autor:
Natália Ferreira de Sousa, Gabrielly Diniz Duarte, Carolina Borsoi Moraes, Cecília Gomes Barbosa, Holli-Joi Martin, Nail N. Muratov, Yuri Mangueira do Nascimento, Luciana Scotti, Lúcio Holanda Gondim de Freitas-Júnior, José Maria Barbosa Filho, Marcus Tullius Scotti
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 912 (2024)
In 2019, the emergence of the seventh known coronavirus to cause severe illness in humans triggered a global effort towards the development of new drugs and vaccines for the SARS-CoV-2 virus. These efforts are still ongoing in 2024, including the pre
Externí odkaz:
https://doaj.org/article/291d71d6f69f4c8c9fca576dbc687759
Autor:
Eduardo José Azevedo Corrêa, Frederico Chaves Carvalho, Júlia Assunção de Castro Oliveira, Suzan Kelly Vilela Bertolucci, Marcus Tullius Scotti, Carlos Henrique Silveira, Fabiana Costa Guedes, Júlio Onésio Ferreira Melo, Raquel Cardoso de Melo-Minardi, Leonardo Henrique França de Lima
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Essential oils (EOs) are a promising source for novel environmentally safe insecticides. However, the structural diversity of their compounds poses challenges to accurately elucidate their biological mechanisms of action. We present a new ch
Externí odkaz:
https://doaj.org/article/30cff3cc2fc549c983573d7b5bc67382
Autor:
Gleycyelly Rodrigues Araújo, Palloma Christine Queiroga Gomes da Costa, Paula Lima Nogueira, Danielle da Nóbrega Alves, Alana Rodrigues Ferreira, Pablo R. da Silva, Jéssica Cabral de Andrade, Natália F. de Sousa, Paulo Bruno Araujo Loureiro, Marianna Vieira Sobral, Damião P. Sousa, Marcus Tullius Scotti, Ricardo Dias de Castro, Luciana Scotti
Publikováno v:
BioTech, Vol 13, Iss 2, p 16 (2024)
Candida species are frequently implicated in the development of both superficial and invasive fungal infections, which can impact vital organs. In the quest for novel strategies to combat fungal infections, there has been growing interest in explorin
Externí odkaz:
https://doaj.org/article/1757b74146974c43a49c6385aac064b8
Autor:
Simony Carvalho Mendonça, Brendo Araujo Gomes, Mariana Freire Campos, Thamirys Silva da Fonseca, Maria Eduarda Alves Esteves, Bruce Veiga Andriolo, Caio Felipe de Araujo Ribas Cheohen, Larissa Esteves Carvalho Constant, Stephany da Silva Costa, Pedro Telles Calil, Amanda Resende Tucci, Thamara Kelcya Fonseca de Oliveira, Alice dos Santos Rosa, Vivian Neuza dos Santos Ferreira, Julia Nilo Henrique Lima, Milene Dias Miranda, Luciana Jesus da Costa, Manuela Leal da Silva, Marcus Tullius Scotti, Diego Allonso, Gilda Guimarães Leitão, Suzana Guimarães Leitão
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 436 (2024)
The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family from Brazilian hot spot regions, provides a promising avenue for bioprospection. Given the pivotal roles of the Spike protein and 3CLpro and PLpro proteases in SARS-
Externí odkaz:
https://doaj.org/article/0277a49c1be843239ec3df752d2d7ce8
Autor:
Roseana A. R. Meireles, Lucas S. Abreu, Joanda Paolla R. e Silva, Andreza B. S. Cavalcanti, Renata Priscila B. de Menezes, Gabriela Cristina S. Rodrigues, Valnês S. Rodrigues Junior, José Iranildo M. de Melo, Massuo Jorge Kato, Vicente Carlos de O. Costa, Marcus Tullius Scotti, Josean F. Tavares
Publikováno v:
Química Nova, Vol 45, Iss 9, Pp 1092-1097 (2022)
Phytochemical study of the roots of Euphorbia phosphorea Mart. (Euphorbiaceae) was carried out through chromatographic techniques, resulting in the isolation of a new ent-abietane diterpene named 11β,12β-dihydroxy-ent-abieta-8(14),13(15)-dien-16,12
Externí odkaz:
https://doaj.org/article/070f5ccd2c1a436ba6baf3b633ae21b9
Autor:
Luiza Tamie Hirata Diethelm, Amanda Bruno da Silva Bellini Ramos, Giovanna Braga de Lorena, Bruna Inácio Trajano, Rafael Dias do Espírito Santo, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fabio Antonio Colombo, Marcos José Marques, Carlos Roque Duarte Correia, Juliana Quero Reimão
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 262 (2024)
Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications, including neurotoxoplasmosis, a leading cause of cerebral lesions in AIDS patients. The current pharmacological treatments for toxoplasmosis face clinical
Externí odkaz:
https://doaj.org/article/e9f6dd7ddd034e3d886af3c318c0ff95
Autor:
Maria Camila Muñoz-Vega, Sofía López-Hernández, Adrián Sierra-Chavarro, Marcus Tullius Scotti, Luciana Scotti, Ericsson Coy-Barrera, Chonny Herrera-Acevedo
Publikováno v:
Molecules, Vol 29, Iss 1, p 179 (2023)
The critical enzyme dihydrofolate reductase-thymidylate synthase in Leishmania major (LmDHFR-TS) serves a dual-purpose role and is essential for DNA synthesis, a cornerstone of the parasite’s reproductive processes. Consequently, the development of
Externí odkaz:
https://doaj.org/article/999e2b63d4f84e6b94ee2cdd1ad25806
Autor:
Rafael Carlos Ferreira, Sâmia Sousa Duarte, Valgrícia Matias de Sousa, Ramon Ramos Marques de Souza, Karinne Kelly Gadelha Marques, Renata Albuquerque de Abrantes, Yuri Mangueira do Nascimento, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti, Josean Fechine Tavares, Juan Carlos Ramos Gonçalves, Marcelo Sobral da Silva, Marianna Vieira Sobral
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1553 (2023)
The characterization and cytotoxicity of the essential oil from Conyza bonariensis (L.) aerial parts (CBEO) were previously conducted. The major compound was (Z)-2-lachnophyllum ester (EZ), and CBEO exhibited significant ROS-dependent cytotoxicity in
Externí odkaz:
https://doaj.org/article/17fc57ea2e7f4e27bfa0afd8002f4d97