Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marcus Schley"'
Autor:
Janet Weber, Marcus Schley, Matthias Casutt, Helmut Gerber, Guido Schuepfer, Roman Rukwied, Wolfgang Schleinzer, Michael Ueberall, Christoph Konrad
Publikováno v:
Anesthesiology Research and Practice, Vol 2009 (2009)
Central neuropathic pain is difficult to treat, but delta 9-Tetrahydrocannabinol (delta 9-THC) may be a promising therapeutic agent. We administered in 172 patients on average 7.5 mg delta 9-THC over 7 months. Of these, 48 patients prematurely withdr
Externí odkaz:
https://doaj.org/article/dff30598fa434e68a03cbfc93cff999b
Autor:
C. Konrad, Lenka Stockinger, Roman Rukwied, Marcus Schley, Wolfgang Schleinzer, Martin Schmelz, Carola Vogel
Publikováno v:
The Journal of Pain. 18:66-78
At-level and above-level hypersensitivity was assessed in patients with chronic complete thoracic spinal cord injury (SCI). Patients were classified using somatosensory mapping (brush, cold, pinprick) and assigned into 2 groups (ie, patients with at-
Autor:
Christoph Konrad, Justus Benrath, James A. Blunk, Christian Menzer, Marcus Schley, M. Dusch, Martin Schmelz, Roman Rukwied
Publikováno v:
Acta Dermato Venereologica. 93:394-399
The nerve fibres underlying histamine-induced itch have not been fully elucidated. We blocked the lateral femoral cutaneous nerve and mapped the skin area unresponsive to mechanical stimulation, but still sensitive to electrically induced pain. Nerve
Autor:
Niclas Sjögren, Roman Rukwied, Martin Schmelz, Christian Geber, C. Konrad, Frank Birklein, L. Gee, Frank L. Rice, Justus Benrath, A. Bayram, Phillip J. Albrecht, Björn Hägglöf, Marcus Schley, M. Dusch
Publikováno v:
European Journal of Pain. 16:1414-1425
Background: Neuropathy can lead not only to impaired function but also to sensory sensitization. We aimed to link reduced skin nerve fibre density in different levels to layer-specific functional impairment in neuropathic pain patients and tried to i
Autor:
Herta Flor, Martin Diers, Marcus Schley, Haili Wang, Pinar Yilmaz, Richard H. Gracely, Kati Thieme, Claudia Rolko, Mariela Rance, Ulrike Kiessling
Publikováno v:
Experimental Brain Research. 218:619-628
Little is known about the effects of successful treatment on brain function in chronic pain. This study examined changes in pain-evoked brain activation following behavioral extinction training in fibromyalgia patients. Using functional magnetic reso
Autor:
Alexandra Mayer, Martin Schmelz, Michael Hirth, Roman Rukwied, Olga Kluschina, Otilia Obreja, Marcus Schley
Publikováno v:
Pain. 152:1856-1863
High-affinity receptors for nerve growth factor (NGF) are found on nociceptors and sympathetic efferents. NGF is known to sensitize nociceptors, increase innervation density, and fire frequency of sympathetic fibers. We explored axonal sensitization
Autor:
Lydia Lauer, Roman Rukwied, Marcus Schley, Martin Diers, Pinar Yilmaz, Herta Flor, Martin Schmelz, Mariela Rance
Publikováno v:
European Journal of Pain. 15:716-723
Background While the etiology of fibromyalgia syndrome (FMS) remains unclear, it is assumed that both peripheral and central components are involved. Aims/methods To investigate central activation patterns following chemically-induced muscle pain we
Autor:
Martin Schmelz, Björn Hägglöf, M. Strupf, Roman Rukwied, Wolfgang Koppert, Barbara Namer, Marcus Schley, M. Dusch
Publikováno v:
Scandinavian Journal of Pain. 1:205-210
Background Anewexperimental protocol of electrically induced pain and hyperalgesia was established to examine orally administered drugs. In a randomized, double-blind, placebo-controlled cross-over study this experimental protocol was used to assess
Publikováno v:
Pain. 148:407-413
Nerve growth factor (NGF) modulates sensitivity and sprouting of nociceptors. We explored the spatial and temporal sensitization induced by NGF injection (1 microg) in human skin. Hyperalgesia was investigated in 16 volunteers (36+/-9 years) at day 1
Autor:
Martin Schmelz, Joachim Schmeck, Matthias Casutt, G. Schüpfer, Christoph Haberthür, Christoph Konrad, M. Dusch, Roman Rukwied, Marcus Schley
Publikováno v:
Anesthesia & Analgesia. 109:880-885
BACKGROUND: Endothelin-1 (ET-1) is a mediator of lung diseases and a potent pulmonary vasoconstrictor. In addition to thromboxane A2, it participates in the formation of lung edema. Both lidocaine and mepivacaine attenuate the increase of pulmonary a