Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marcus S, Dyer"'
Autor:
Rosemary M. Clark, Courtney M. Clark, Katherine E.A. Lewis, Marcus S. Dyer, Jyoti A. Chuckowree, Joshua A. Hoyle, Catherine A. Blizzard, Tracey C. Dickson
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 11, Pp 1985-1999 (2023)
Abstract Objective Neuropeptide Y (NPY) is a 36 amino acid peptide widely considered to provide neuroprotection in a range of neurodegenerative diseases. In the fatal motor neuron disease amyotrophic lateral sclerosis (ALS), recent evidence supports
Externí odkaz:
https://doaj.org/article/246d624c3fe4468296d9e6f8d246f7ba
Autor:
Marcus S. Dyer, G. Lorenzo Odierna, Rosemary M. Clark, Adele Woodhouse, Catherine A. Blizzard
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Amyotrophic Lateral Sclerosis (ALS) is an incurable disease characterized by relentlessly progressive degeneration of the corticomotor system. Cortical hyperexcitability has been identified as an early pre-symptomatic biomarker of ALS. This suggests
Externí odkaz:
https://doaj.org/article/a373b867b43d4c239e7494e29d163436
Publikováno v:
Brain Sciences, Vol 11, Iss 7, p 883 (2021)
Amyotrophic lateral sclerosis (ALS) is defined by the destruction of upper- and lower motor neurons. Post-mortem, nearly all ALS cases are positive for cytoplasmic aggregates containing the DNA/RNA binding protein TDP-43. Recent studies indicate that
Externí odkaz:
https://doaj.org/article/dc5d963691b340b8840cbb46785264f2
Autor:
Emily E. Handley, Laura A. Reale, Jyoti A. Chuckowree, Marcus S. Dyer, Grace L. Barnett, Courtney M. Clark, William Bennett, Tracey C. Dickson, Catherine A. Blizzard
Publikováno v:
Molecular Neurobiology. 59:2962-2976
Amyotrophic lateral sclerosis (ALS) attacks the corticomotor system, with motor cortex function affected early in disease. Younger females have a lower relative risk of succumbing to ALS than males and older females, implicating a role for female sex
Autor:
Laura A. Reale, Marcus S. Dyer, Sharn E. Perry, Kaylene M. Young, Tracey C. Dickson, Adele Woodhouse, Catherine A. Blizzard
Publikováno v:
Progress in Neurobiology. 226:102449
Autor:
Laura A Reale, Marcus S Dyer, Tracey C. Dickson, Catherine A. Blizzard, Katherine E. Lewis, Adele Woodhouse, Adam K. Walker
Publikováno v:
Journal of Neurochemistry. 157:1300-1315
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease pathologically characterised by mislocalisation of the RNA-binding protein TAR-DNA-binding protein 43 (TDP-43) from the nucleus to the cytoplasm. Changes to neuronal excitabil
Autor:
Emily E, Handley, Laura A, Reale, Jyoti A, Chuckowree, Marcus S, Dyer, Grace L, Barnett, Courtney M, Clark, William, Bennett, Tracey C, Dickson, Catherine A, Blizzard
Publikováno v:
Molecular neurobiology. 59(5)
Amyotrophic lateral sclerosis (ALS) attacks the corticomotor system, with motor cortex function affected early in disease. Younger females have a lower relative risk of succumbing to ALS than males and older females, implicating a role for female sex
Autor:
Catherine A. Blizzard, Katherine E. Lewis, Tracey C. Dickson, Marcus S Dyer, Adele Woodhouse, Adam K. Walker
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease pathologically characterised by mislocalisation of the RNA binding protein TAR-DNA binding protein 43 (TDP-43) from the nucleus to the cytoplasm. Changes to neuronal excitabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748f940a8c9bf17aed03a19b4162c887
https://doi.org/10.1101/2020.06.11.147439
https://doi.org/10.1101/2020.06.11.147439
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat malignancies t