Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Marcus R. Vowels"'
Autor:
Melissa Gabriel, Marcus R. Vowels, Tracey A. O'Brien, Heather Tapp, D. Baker, Cecilia Oswald, Lochie Teague, T.E. Petterson, R. Bolton-Jones, Peter J. Shaw, Karin Tiedemann
Publikováno v:
Bone Marrow Transplantation. 43:207-215
Unrelated umbilical cord blood (UCB) is an alternative stem cell source for paediatric patients lacking a matched related or unrelated marrow donor. We report the results of all paediatric unrelated UCB transplants performed in Australia and New Zeal
Publikováno v:
Transfusion Medicine. 15:69-82
Aim Since 1995, the SCBB has used three protocols to screen CB for contaminating microbes. The protocols differed in the number of culture bottles inoculated and sample volume used. The aim of this study was to compare microbial detection rates for e
Autor:
Glenn M. Marshall, Richard J. Cohn, Toby Trahair, Kristen A Neville, Susan L. Carroll, Marcus R. Vowels, Karen Johnston, Susan Russell
Publikováno v:
Bone Marrow Transplantation. 40:741-746
We retrospectively analysed the outcomes of children transplanted for high-risk neuroblastoma (NB) at a single institution predominantly transplanted with total body irradiation and chemotherapy. The aims of this study were to determine the prognosti
Publikováno v:
Bone Marrow Transplantation. 40:729-734
Over the past decade umbilical cord blood (UCB) has been increasingly used as a source of haematopoietic stem cells (HSCs) for patients who require a HSC transplant but do not have an HLA-matched donor. It was anticipated that using UCB as an alterna
Unrelated cord blood transplantation for childhood acute myeloid leukemia: a Eurocord Group analysis
Autor:
Kah-Wah Chan, Alexandra H. Filipovich, Franca Fagioli, Irina Ionescu, Federico Garnier, Isaac Yaniv, Anna Paola Iori, Amparo Verdeguer, Pedro Pimentel, Tsuneo A. Takahashi, Eliane Gluckman, Euripedes Ferreira, Eric L. Sievers, Blanca Diez, Franco Locatelli, Jean Pierre Jouet, Alexandra Machado, Marcus R. Vowels, Sylvie Chevret, Pierre Bordigoni, William Arcese, Ricardo Pasquini, Joseph Rosenthal, Peter J. Shaw, Chiara Messina, Gérard Michel, Vanderson Rocha, Juan Ortega
Publikováno v:
Blood. 102:4290-4297
Results of unrelated cord blood transplantation (UCBT) in childhood acute myeloid leukemia (AML) have not been previously reported. We analyzed 95 children receiving UCB transplants for AML (20 in first complete remission [CR1], 47 in CR2, and 28 in
Autor:
Alison M. Rice, Marcus R. Vowels, Julie A. Wood, Christopher G. Milross, Cathryn J. Collins, Jamie Case, Robert E. Nordon
Publikováno v:
British Journal of Haematology. 114:433-443
A clinical goal for ex vivo expansion of cord blood (CB) CD34(+) cells is to shorten the period of neutropenia and thrombocytopenia following myeloablative therapy and transplantation. Prolongation of cytokine expansion leads to the production of gre
Autor:
Julie A. Wood, Robert E. Nordon, Marcus R. Vowels, Christopher G. Milross, Alison M. Rice, Jamie Case, Cathryn J. Collins
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 10:157-165
Cytokine-mediated expansion has been proposed and successfully used to facilitate engraftment post transplantation. This study examined whether cryopreservation following expansion has a detrimental effect on the ability of cells to engraft, using th
Autor:
Christopher G. Milross, Cathryn J. Collins, Nigel F. McCarthy, Julie A. Wood, Marcus R. Vowels, Alison M. Rice
Publikováno v:
Transplantation. :927-935
BACKGROUND Transplantation of human hematopoietic stem cells is the only true test of their long-term repopulation potential. Models are readily available to evaluate murine hematopoietic stem cells, but few exist that allow reliable quantification o
Publikováno v:
Cytometry. 43:69-81
Background Multiple cytokines are required for the growth and development of hematopoietic cells. The effect of many cytokines depends on the activity of other signaling pathways. These interactions are quantified using factorial experimental design
Publikováno v:
Hematology and Cell Therapy. 39:193-197
To determine the optimal cell population for cytokine mediated expansion, we compared the use of Magnetic Cell Sorting (MACS) system enriched CD34+ human umbilical cord blood (HUCB) cells with that of MACS enriched, flow purified CD34+ HUCB cells. Bo