Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marcus P. Kelly"'
Autor:
Lauric Haber, Kara Olson, Marcus P. Kelly, Alison Crawford, David J. DiLillo, Richard Tavaré, Erica Ullman, Shu Mao, Lauren Canova, Olga Sineshchekova, Jennifer Finney, Arpita Pawashe, Supriya Patel, Ryan McKay, Sahar Rizvi, Ermelinda Damko, Danica Chiu, Kristin Vazzana, Priyanka Ram, Katja Mohrs, Amanda D’Orvilliers, Jenny Xiao, Sosina Makonnen, Carlos Hickey, Cody Arnold, Jason Giurleo, Ya Ping Chen, Courtney Thwaites, Drew Dudgeon, Kevin Bray, Ashique Rafique, Tammy Huang, Frank Delfino, Aynur Hermann, Jessica R. Kirshner, Marc W. Retter, Robert Babb, Douglas MacDonald, Gang Chen, William C. Olson, Gavin Thurston, Samuel Davis, John C. Lin, Eric Smith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract T-cell-redirecting bispecific antibodies have emerged as a new class of therapeutic agents designed to simultaneously bind to T cells via CD3 and to tumor cells via tumor-cell-specific antigens (TSA), inducing T-cell-mediated killing of tumo
Externí odkaz:
https://doaj.org/article/13db8e3e17e043ffbbadbbb6bb988d63
Autor:
Marcus D. Kelly, Matthew R. Pawlak, Kevin H. Zhan, Ghaidan A. Shamsan, Wendy R. Gordon, David J. Odde
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036102-036102-11 (2024)
Cell migration is the major driver of invasion and metastasis during cancer progression. For cells to migrate, they utilize the actin–myosin cytoskeleton and adhesion molecules, such as integrins and CD44, to generate traction forces in their envir
Externí odkaz:
https://doaj.org/article/1e07d54b25c34fafa4f2d643b0677027
Autor:
Kaja Kostyrko, Marta Román, Alex G. Lee, David R. Simpson, Phuong T. Dinh, Stanley G. Leung, Kieren D. Marini, Marcus R. Kelly, Joshua Broyde, Andrea Califano, Peter K. Jackson, E. Alejandro Sweet-Cordero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract KRAS is a frequent driver in lung cancer. To identify KRAS-specific vulnerabilities in lung cancer, we performed RNAi screens in primary spheroids derived from a Kras mutant mouse lung cancer model and discovered an epigenetic regulator Ubiq
Externí odkaz:
https://doaj.org/article/bfd9eceda508466c9e02d6a2c91e89f7
Autor:
Matthew R. Pawlak, Adam T. Smiley, Maria Paz Ramirez, Marcus D. Kelly, Ghaidan A. Shamsan, Sarah M. Anderson, Branden A. Smeester, David A. Largaespada, David J. Odde, Wendy R. Gordon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Mechanical forces drive critical cellular processes that are reflected in mechanical phenotypes, or mechanotypes, of cells and their microenvironment. We present here “Rupture And Deliver” Tension Gauge Tethers (RAD-TGTs) in which flow c
Externí odkaz:
https://doaj.org/article/1fd6216c1397488692642b2a66cb4e0c
Autor:
Gavin Thurston, Richard Tavare, Marcus P Kelly, Sosina Makonnen, Carlos Hickey, T Cody Arnold, Jason T Giurleo, Makenzie Danton, Christian Granados, Ishita Chatterjee, Drew Dudgeon, Marc W Retter, Dangshe Ma, William C Olson, Jessica R Kirshner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/e9dd493986824827a77c38864a866af9
Autor:
Gavin Thurston, Richard Tavare, Marcus P Kelly, Sosina Makonnen, Carlos Hickey, T Cody Arnold, Jason T Giurleo, Makenzie Danton, Christian Granados, Ishita Chatterjee, Drew Dudgeon, Marc W Retter, Dangshe Ma, William C Olson, Jessica R Kirshner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) blocking antibodies including cemiplimab have generated profound clinical activity across diverse cancer types. Tumorous PD-L1 expression, as assessed by immunohistoche
Externí odkaz:
https://doaj.org/article/95ca884fb1ff45408c623ba0079af2dc
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Assessment of immune-cell subsets within the tumor immune microenvironment is a powerful approach to better understand cancer immunotherapy responses. However, the use of biopsies to assess the tumor immune microenvironment poses challenges, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a28c1ce088d993bb73c7f8fe1e2f64
https://doi.org/10.1158/2326-6066.c.6550910.v1
https://doi.org/10.1158/2326-6066.c.6550910.v1
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Supplementary Data from Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc99ef8fb49a9843c409980f336132eb
https://doi.org/10.1158/2326-6066.22545326.v1
https://doi.org/10.1158/2326-6066.22545326.v1
Autor:
Gavin Thurston, William Olson, Christopher Daly, Douglas MacDonald, Thomas Nittoli, Arthur Kunz, Ashique Rafique, Jessica R. Kirshner, Marcus P. Kelly, Joel Martin, Frank Delfino, Andres E. Perez Bay, Nithya Thambi, Julian Andreev
Proteasomal degradation inhibitors, Bortezomib and Lactacystin had little or no effect on PRLR turnover.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eb2f6ae3fa37e4537ad5c76a2cab15
https://doi.org/10.1158/1535-7163.22507911.v1
https://doi.org/10.1158/1535-7163.22507911.v1
Autor:
Jessica R. Kirshner, Gavin Thurston, Pamela A. Trail, Thomas Nittoli, Jason T. Giurleo, Christopher D'Souza, Arthur Kunz, Julian Andreev, Ishita Chatterjee, Terra B. Potocky, Jing Shan, Frank Delfino, Yu Wang, Sumreen Jalal, Sandra Coetzee, Sosina Makonnen, Carlos Hickey, Marcus P. Kelly
Supplementary Figures S1 - S8 as referenced in the main article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02543ae3f8c659cbf2d85cbb22484266
https://doi.org/10.1158/1535-7163.22503190
https://doi.org/10.1158/1535-7163.22503190