Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marcus Otte"'
Autor:
Thomas Mrowiec, Sharon Ruane, Simon Schallenberg, Gabriel Dernbach, Rumyana Todorova, Cornelius Böhm, Walter de Back, Blanca Pablos, Roman Schulte-Sasse, Ivana Trajanovska, Adelaida Creosteanu, Emil Barbuta, Marcus Otte, Christian Ihling, Hans Juergen Grote, Juergen Scheuenpflug, Viktor Matyas, Maximilian Alber, Frederick Klauschen
Publikováno v:
Cancer Research. 82:457-457
Background: Automated cell-level characterization of the tumor microenvironment (TME) at scale is key to data-driven immuno-oncology. Artificial intelligence (AI)-powered analysis of hematoxylin and eosin (H&E) images scales and has recently been tra
Autor:
Marcus Otte
Publikováno v:
Quaestiones Disputatae. 6:44-61
Autor:
Aslihan Gerhold-Ay, Elena Svenson, Corinna M Wolf, Anja von Heydebreck, Glenn Beeman, P. Alexander Rolfe, Marcus Otte, Juergen Scheuenpflug, M. Ruisi, Ti Cai, Thomas Mrowiec, Parantu K. Shah, Hans Juergen Grote, Violeta Labarta-Beceiro
Publikováno v:
Journal of Clinical Oncology. 38:e21539-e21539
e21539 Background: Assessment of programmed death ligand-1 (PD-L1) protein expression using immunohistochemistry (IHC)-based tests is currently the only approved biomarker guiding treatment of non-small cell lung cancer (NSCLC) with checkpoint inhibi
Autor:
Marcus Otte, Maria Waldhoer, Sheri L. Holmen, Meenhard Herlyn, Mizuho Fukunaga-Kalabis, Christian Wels, Helmut Schaider, Shripad Joshi, Christine Beham-Schmid
Publikováno v:
International Journal of Cancer. 137:1503-1508
US28, a constitutively active G-protein-coupled receptor encoded by the human cytomegalovirus, leads to mechanistically unknown programmed cell death. Here we show that expression of wild-type US28 in human melanoma cells leads to apoptotic cell deat
Autor:
Shripad, Joshi, Christian, Wels, Christine, Beham-Schmid, Mizuho, Fukunaga-Kalabis, Sheri L, Holmen, Marcus, Otte, Meenhard, Herlyn, Maria, Waldhoer, Helmut, Schaider
Publikováno v:
International journal of cancer. 137(6)
US28, a constitutively active G-protein-coupled receptor encoded by the human cytomegalovirus, leads to mechanistically unknown programmed cell death. Here we show that expression of wild type US28 in human melanoma cells leads to apoptotic cell deat
Autor:
Marcus Otte
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493926800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f799eecb6ea72f2f08b13d9e67e50ac5
https://doi.org/10.1007/7653_2014_30
https://doi.org/10.1007/7653_2014_30
Autor:
Marcus Otte, Klaus Pantel
Publikováno v:
Seminars in Cancer Biology. 11:327-337
The decision as to whether systemic adjuvant therapy should be applied in breast cancer patients for secondary prevention of metastatic relapse is based solely on the statistical prognosis. For this reason, the direct identification of minimal residu
Autor:
Friedrich Lottspeich, Kristin Bauer, Jörg Hagmann, Christoph Eckerskorn, Marcus Otte, Wolfgang Siess, Michael A. A. Kratzer, Georg J. Arnold, Karin Luber de Quintana
Publikováno v:
Blood. 96:4236-4245
A 38-kd protein that associates with F-actin structures in activated platelets and endothelial cells was purified, cloned, and characterized. The protein contains an N-terminal PDZ motif, a large intervening sequence, and a C-terminal LIM domain and
Autor:
Dieter K. Hossfeld, Christoph Wagener, Gunter Schuch, Nerbil Kilic, Thorsten Mende, Klaus Pantel, Udo Schumacher, Süleyman Ergün, Philippe Schafhausen, Ursula M. Gehling, Birgit Schäfer, Katrin Kluge, Walter Fiedler, Marcus Otte
Publikováno v:
Blood. 95:3106-3112
Recent findings support the hypothesis that the CD34+-cell population in bone marrow and peripheral blood contains hematopoietic and endothelial progenitor and stem cells. In this study, we report that human AC133+ cells from granulocyte colony-stimu
Autor:
Marcus Otte, P. Koefinger, M. Stefan, Erika Richtig, Gábor Méhes, Helmut Kerl, Helmut Schaider, Christian Wels, Sabine Damm
Publikováno v:
The Journal of investigative dermatology. 130(7)
The regulation of CD44v6, a variant of the CD44 family of glycosylated adhesion molecules, through hepatocyte growth factor (HGF) has implications for motility in primary human melanocytes. We show that exposure of primary human melanocytes to HGF re