Brain-derived neurotrophic factor rs6265 (Val66Met) single nucleotide polymorphism as a master modifier of human pathophysiology

Autor: CristiL Galindo, Van Thuan Nguyen, Braxton Hill, Naiya Sims, Aaron Heck, Marcus Negron, Claire Lusk

Publikováno v: Neural regeneration research. 18(1)

Brain-derived neurotrophic factor is the most prevalent member of the nerve growth factor family. Since its discovery in 1978, this enigmatic molecule has spawned more than 27,000 publications, most of which are focused on neurological disorders. Bra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c50e1571697098a31ebdad4b725af3
https://pubmed.ncbi.nlm.nih.gov/35799516

Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice

Autor: Lauren E Gansereit, Eric C. Rouchka, Imamulhaq Brula, Lin Zhong, Marcus Negron, Cristi L Galindo, Aaron Heck, Cassandra P. Awgulewitsch, Simran Banga, Gabrielle Kitchen, Jeffrey Kristensen, Van Thuan Nguyen, Frank J. Raucci, Julia L Chariker

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7002, p 7002 (2021)
Volume 22
Issue 13

Brain-derived neurotrophic factor (BDNF) is a pleiotropic neuronal growth and survival factor that is indispensable in the brain, as well as in multiple other tissues and organs, including the cardiovascular system. In approximately 30% of the genera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea45e8d31c506fbacad13d86bd57ac03
https://pubmed.ncbi.nlm.nih.gov/34210092