Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marcus Luxemburg"'
Autor:
Basia Galinski, Marcus Luxemburg, Yosef Landesman, Bruce Pawel, Katherine J. Johnson, Stephen R. Master, Kevin W. Freeman, David M. Loeb, Jean M. Hébert, Daniel A. Weiser
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101114- (2021)
Across many cancer types in adults, upregulation of the nuclear-to-cytoplasmic transport protein Exportin-1 (XPO1) correlates with poor outcome and responsiveness to selinexor, an FDA-approved XPO1 inhibitor. Similar data are emerging in childhood ca
Externí odkaz:
https://doaj.org/article/df22e3a1000a4cbeba345adf608973b1
Publikováno v:
Cancer Research. 78:3193-3193
Background: Neuroblastoma is an embryonic tumor of the peripheral nervous system. Comparative proteomics of high-risk neuroblastoma patients with poor prognosis outcomes demonstrated increased expression of Exportin-1 (XPO1), a nuclear transport prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a158aa4756e0fd40e8b80028cf3d39
https://doi.org/10.1158/1538-7445.am2018-3193
https://doi.org/10.1158/1538-7445.am2018-3193
Publikováno v:
Cancer Research. 77:1938-1938
Background: Half of patients with high-risk neuroblastoma succumb to disease, yet these patients with inferior outcome cannot be identified at diagnosis despite contemporary risk stratification that integrates MYCN copy number status, tumor histology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05290b08686cd21963d306ac5827011a
https://doi.org/10.1158/1538-7445.am2017-1938
https://doi.org/10.1158/1538-7445.am2017-1938