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Autor:
Viktor Ljungström, Frederic Davi, Kostas Stamatopoulos, Diego Cortese, Nicholas Chiorazzi, Johan Rung, Šárka Pospíšilová, Xiao-Jie Yan, Antonia Kalushkova, Gunnar Juliusson, Karin E. Smedby, Gunilla Enblad, Jonathan C. Strefford, Karla Plevová, Sina Bondza, Lesley-Ann Sutton, Brigitta Sander, Linda Arngården, Rebeqa Gunnarsson, Anton W. Langerak, Larry Mansouri, Jimmy Larsson, Erin Young, Richard Rosenquist, Elin Falk-Sörqvist, Helena Jernberg-Wiklund, Marcus Lars Vittorio Nilsson, Alice F. Muggen, Paolo Ghia, Sujata Bhoi, Ola Söderberg, Chrysoula Belessi, Mats Hellström, Peter Lönn
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine; 212(6), pp 833-843 (2015)
Journal of Experimental Medicine; 212(6), pp 833-843 (2015)
Mansouri et al. applied targeted deep sequencing to identify mutations within NF-κB core complex genes in CLL. NFKBIE, the gene encoding the inhibitory IκBε molecule, was most frequently mutated, especially in poor-prognostic subgroups of CLL. The