Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marcus J. Wirth"'
Autor:
Marcus J. Wirth, Andreas Kriebel, Hermann Wagner, Jörg Mey, Katharina Kriebel, Tobias Ackels, Thomas Kuenzel
Publikováno v:
Hearing research. 393
GABAergic transmission changes from depolarization to hyperpolarization in most vertebrate brain regions during development. By contrast, in the auditory brainstem of chicken a depolarizing effect of GABA persists after hatching. Since auditory brain
Publikováno v:
Journal of Neuroscience Methods. 169:55-64
We present a method to identify specific sub-populations of auditory neurons in a mixed primary cell culture of the chicken brainstem, allowing the study of individual neurons with a known identity in vitro. To label specific afferent cell types, we
Publikováno v:
Proceedings of the National Academy of Sciences. 102:3064-3069
The transcellular signaling of neurotrophins is postulated, but evidence is scarce. We now show that a small number of NT4- and BDNF-overexpressing neurons in the cortical explant of thalamocortical cocultures rapidly evoked a Trk receptor-dependent
Publikováno v:
e-Neuroforum. 10:261-267
Zusammenfassung Die GABAergen inhibitorischen Interneurone der Hirnrinde bilden eine morphologisch, neurochemisch und elektrophysiologisch heterogene Klasse von Neuronen. Die Diversität ist nicht allein genetisch determiniert, sondern wird während
Publikováno v:
Cerebral Cortex. 14:342-351
The differentiation of cortical interneurons is controlled by environmental factors. Here, we describe the role of activity and neurotrophins in regulating parvalbumin (PARV) expression using organotypic cultures (OTC) of rat visual cortex as model s
EP 86. Interneuron synaptopathy induced by the pro-inflammatory cytokine LIF in developing neocortex
Autor:
Maren Engelhardt, Nicoletta Berardi, Alexander Jack, Lamberto Maffei, Petra Wahle, Silke Patz, Mohammad I. K. Hamad, J. König, N. Jamann, Marcus J. Wirth, G. di Cristo, Jochen Grabert
Publikováno v:
Clinical Neurophysiology. 127:e278-e279
An inflammatory episode during brain development is discussed as first hit which could trigger a higher susceptibility for epilepsy or development of mental disorders. We addressed the early developmental actions of an IL-6 type pro-inflammatory cyto
Autor:
Petra Wahle, Marcus J. Wirth
Publikováno v:
Journal of Neuroscience Methods. 125:45-54
Our aim is the biolistic transfection of organotypic cultures of rat visual cortex with plasmids coding for neurotrophic factors, which then become expressed for limited periods of time during postnatal ontogenesis. Out of two commercially available
Publikováno v:
European Journal of Neuroscience. 10:1457-1464
Epigenetic factors are known to influence the differentiation of neocortical neurons. The present study analyses the role of spontaneous bioelectrical activity (SBA) and neurotrophic factors on the expression of neuropeptide Y (NPY) in rat visual cor
Autor:
Christian Riedel, Petra Wahle, Jan-Niklas Schulz, Mohammad I. K. Hamad, T. Habijan, Martin Krause, Michael Hollmann, Marcus J. Wirth, Claudius Conrads, Thomas Veitinger, Zhan-Lu Ma-Högemeier
Publikováno v:
Development (Cambridge, England). 138(19)
Glutamatergic transmission converging on calcium signaling plays a key role in dendritic differentiation. In early development, AMPA receptor (AMPAR) transcripts are extensively spliced and edited to generate subunits that differ in their biophysical
Publikováno v:
Brain research. 1302
In the auditory system voltage-activated currents mediated by potassium channels Kv1.1 and Kv3.1b and their interaction with sodium inward currents play a crucial role for computational function. However, it is unresolved how these potassium channels