Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Marcus J. Swann"'
Publikováno v:
Microorganisms, Vol 12, Iss 11, p 2223 (2024)
Eschar and slough in wounds serve as a reservoir for microorganisms and biofilms, damaged/devitalised cells, and inflammatory chemokines/cytokines, which work to initiate and prolong persistent inflammation and increase the risk of infection. Biofilm
Externí odkaz:
https://doaj.org/article/f58bdf2586734785a10a2bc2b01e73b5
Publikováno v:
Birchenough, H L, Swann, M J, Zindy, E, Day, A J & Jowitt, T A 2020, ' Enhanced avidin binding to lipid bilayers using PDP-PE lipids with PEG-biotin linkers ', Nanoscale Advances . https://doi.org/10.1039/D0NA00060D
Nanoscale Advances, 2 (4
Nanoscale Advances, 2 (4
We have shown using SEEC microscopy that avidin addition to Biotinyl-Cap-PE lipids forms clusters, reducing the levels of association. By using PDP-PE lipids with PEG linkers, we have achieved much higher avidin levels with no clustering effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd7601f47c979e3ac2f36b74058f352
https://research.manchester.ac.uk/en/publications/a683dde9-0cf5-40a6-9f4f-7d0465d213ee
https://research.manchester.ac.uk/en/publications/a683dde9-0cf5-40a6-9f4f-7d0465d213ee
Publikováno v:
'Biochemical Journal ', vol: 473, pages: 4473-4491 (2016)
During the activation of complement C4 to C4b, the exposure of its thioester domain (TED) is crucial for the attachment of C4b to activator surfaces. In the C4b crystal structure, TED forms an Arg104–Glu1032 salt bridge to tether its neighbouring m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa34d03790bf257550bc234ccc3c151f
https://doi.org/10.1042/bcj20160744
https://doi.org/10.1042/bcj20160744
Autor:
Angelika Kunze, Lewis E. Johnson, Malkiat S. Johal, Marcus J. Swann, Hannah K. Wayment-Steele, Yujia Jing, Björn Agnarsson, Sofia Svedhem
Publikováno v:
Langmuir. 32:1771-1781
Aluminum has attracted great attention recently as it has been suggested by several studies to be associated with increased risks for Alzheimer's and Parkinson's disease. The toxicity of the trivalent ion is assumed to derive from structural changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4948e83b9911f8ca8b78f625732bb4
https://doi.org/10.1021/acs.langmuir.5b03999
https://doi.org/10.1021/acs.langmuir.5b03999
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
The biophysical characterization of protein–ligand interactions in solution using techniques such as thermal shift assay, or on surfaces using, for example, dual polarization interferometry, plays an increasingly important role in complementing cry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7dd237d61cf73066fef36672d163a0
https://doi.org/10.1107/s1399004714016617
https://doi.org/10.1107/s1399004714016617
Publikováno v:
Falk, M, Sultana, R, Swann, M J, Freeman, N J & Mount, A 2016, ' Nanoband array electrode as a platform for high sensitivity enzyme-based glucose biosensing ', Bioelectrochemistry, vol. 112, pp. 100-105 . https://doi.org/10.1016/j.bioelechem.2016.04.002
We describe a novel glucose biosensor based on a nanoband array electrode design, manufactured using standard semiconductor processing techniques, and bio-modified with glucose oxidase immobilized at the nanoband electrode surface. The nanoband array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a609c7219a949c1ab61b2fd93d8a75
https://hdl.handle.net/20.500.11820/2613fddc-162a-4d50-b1a6-aca234cfb1f0
https://hdl.handle.net/20.500.11820/2613fddc-162a-4d50-b1a6-aca234cfb1f0
Autor:
Melissa K. Corbett, Simon Ameer-Beg, James Hunt, Rebecca L. Beavil, Marcus J. Swann, Robert E. Dale, Brian J. Sutton, Klaus Suhling, Andrew J. Beavil, James A. Levitt, Anthony H. Keeble
Publikováno v:
Journal of Biological Chemistry. 287:17459-17470
IgE binding to its high affinity receptor FcϵRI on mast cells and basophils is a key step in the mechanism of allergic disease and a target for therapeutic intervention. Early indications that IgE adopts a bent structure in solution have been confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ac26fcfdb445c4504c97e4c4d4a815
https://doi.org/10.1074/jbc.m111.331967
https://doi.org/10.1074/jbc.m111.331967
Publikováno v:
Analytical Chemistry. 83:6267-6274
We have determined the kinetics and affinity of binding of PH-PLCδ(1) to the PIP(2) headgroup lipids using an optical surface-sensitive technique in a time-resolved manner. The use of dual polarization interferometry to probe supported lipid bilayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf718e3202b0631db4434baf5edfa5
https://doi.org/10.1021/ac2009178
https://doi.org/10.1021/ac2009178
Autor:
Yoonkyung Park, Tzong-Hsien Lee, Daniel J. Hirst, Marie-Isabel Aguilar, Kyung-Soo Hahm, Sharon Unabia, Marcus J. Swann
Publikováno v:
European Biophysics Journal. 40:503-514
The effect of acyl chain structure and bilayer phase state on binding and penetration by the peptide HPA3 was studied using dual polarisation interferometry. This peptide is an analogue of Hp(2-20) derived from the N-terminus of Helicobacter pylori r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab0df51119c62f90405611dc3167933
https://doi.org/10.1007/s00249-010-0664-1
https://doi.org/10.1007/s00249-010-0664-1
Autor:
Frances Separovic, Marcus J. Swann, Tzong-Hsien Lee, John D. Gehman, Christine Heng, Marie-Isabel Aguilar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1798(10):1977-1986
Effective antimicrobial peptides (AMPs) distinguish between the host and microbial cells, show selective antimicrobial activity and exhibit a fast killing mechanism. Although understanding the structure–function characteristics of AMPs is important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477af4f978531a53d248d964d9fcab7b