Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Marcus Iken"'
Autor:
Stefanie Steinbauer, Alice König, Cathrina Neuhauser, Bettina Schwarzinger, Herbert Stangl, Marcus Iken, Julian Weghuber, Clemens Röhrl
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cholesterol deposition in intimal macrophages leads to foam cell formation and atherosclerosis. Reverse cholesterol transport (RCT), initiated by efflux of excess cholesterol from foam cells, counteracts atherosclerosis. However, targeting R
Externí odkaz:
https://doaj.org/article/00bf50f0f31c46ada9dc0a8e8d00b5e6
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116612- (2024)
Drosophila melanogaster, or the fruit fly, is widely used for modeling numerous human diseases, such as neurodegeneration, tumor development, cachexia, and intestinal dysfunction. It is a suitable model organism for research targeting the physiology
Externí odkaz:
https://doaj.org/article/3f356dba026d441781ebcabd5688436e
Autor:
Bernhard Blank-Landeshammer, Gerald Klanert, Lisa Mitter, Sophia Turisser, Nicolas Nusser, Alice König, Marcus Iken, Julian Weghuber
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1917 (2022)
Intestinal absorption is intrinsically low for lipophilic micronutrients and phytochemicals. Plant extracts acting as bioavailability enhancers can complement for this deficiency by modulation of both, physicochemical and biochemical parameters, in t
Externí odkaz:
https://doaj.org/article/d7d2cd681690464683e6d88942cf6242
Autor:
Roland Hager, Johannes Pitsch, Jakob Kerbl-Knapp, Cathrina Neuhauser, Nicole Ollinger, Marcus Iken, Josef Ranner, Verena Mittermeier-Kleßinger, Corinna Dawid, Peter Lanzerstorfer, Julian Weghuber
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 809 (2021)
Bioactive plant compounds and extracts are of special interest for the development of pharmaceuticals. Here, we describe the screening of more than 1100 aqueous plant extracts and synthetic reference compounds for their ability to stimulate or inhibi
Externí odkaz:
https://doaj.org/article/d716287373894782ad155f36bbdf6c5c
Autor:
Verena Stadlbauer, Cathrina Neuhauser, Tobias Aumiller, Alexander Stallinger, Marcus Iken, Julian Weghuber
Publikováno v:
Molecules, Vol 26, Iss 14, p 4346 (2021)
Type 2 diabetes mellitus (T2DM) is linked to insulin resistance and a loss of insulin sensitivity, leading to millions of deaths worldwide each year. T2DM is caused by reduced uptake of glucose facilitated by glucose transporter 4 (GLUT4) in muscle a
Externí odkaz:
https://doaj.org/article/577c2f6faa3940a5a2ebc0027a97a12f
Autor:
Clemens Röhrl, Flora Stübl, Martin Maier, Bettina Schwarzinger, Clemens Schwarzinger, Johannes Pitsch, Peter Lanzerstorfer, Marcus Iken, Julian Weghuber
Publikováno v:
Nutrients, Vol 12, Iss 1, p 150 (2020)
The transport of hydrophobic compounds to recipient cells is a critical step in nutrient supplementation. Here, we tested the effect of phospholipid-based emulsification on the uptake of hydrophobic compounds into various tissue culture cell lines. I
Externí odkaz:
https://doaj.org/article/ac05ede18e4d4710a693a6e7334df7c7
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182788 (2017)
Insulin resistance and β cell failure are the main causes of elevated blood glucose levels in Type 2 diabetes mellitus (T2DM), a complex and multifactorial metabolic disease. Several medications to treat or reduce the symptoms of T2DM are used, incl
Externí odkaz:
https://doaj.org/article/53a5186680894137b691102e90788cd4
Autor:
Alice König, Bettina Schwarzinger, Verena Stadlbauer, Peter Lanzerstorfer, Marcus Iken, Clemens Schwarzinger, Peter Kolb, Stephan Schwarzinger, Katharina Mörwald, Susanne Brunner, Otmar Höglinger, Daniel Weghuber, Julian Weghuber
Publikováno v:
Nutrients, Vol 11, Iss 7, p 1512 (2019)
Inhibition of intestinal glucose resorption can serve as an effective strategy for the prevention of an increase in blood glucose levels. We have recently shown that various extracts prepared from guava (Psidium guajava) inhibit sodium-dependent gluc
Externí odkaz:
https://doaj.org/article/11e75ec233bc4cdebc9ea6593d7cfd47
Autor:
Renate Haselgrübler, Verena Stadlbauer, Flora Stübl, Bettina Schwarzinger, Ieva Rudzionyte, Markus Himmelsbach, Marcus Iken, Julian Weghuber
Publikováno v:
Molecules, Vol 23, Iss 10, p 2605 (2018)
Diabetes mellitus (DM) and consequential cardiovascular diseases lead to millions of deaths worldwide each year; 90% of all people suffering from DM are classified as Type 2 DM (T2DM) patients. T2DM is linked to insulin resistance and a loss of insul
Externí odkaz:
https://doaj.org/article/8d22f9de212f40a295529ee3fd03d1b5
Autor:
Julia Bitzegeio, Dorothea Bankwitz, Kathrin Hueging, Sibylle Haid, Christiane Brohm, Mirjam B Zeisel, Eva Herrmann, Marcus Iken, Michael Ott, Thomas F Baumert, Thomas Pietschmann
Publikováno v:
PLoS Pathogens, Vol 6, p e1000978 (2010)
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined. Virus cell entry involves human scavenger receptor class B type I (SR-BI), CD81, claudin-1 and o
Externí odkaz:
https://doaj.org/article/8993a7a785aa4054a305c13b2cffd220