Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Marcus Ho Yin Wong"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
The proton motive force (PMF) is a critical electrochemical gradient involved in bacterial energy metabolism. Here, Miaomiao Wang, Edward Wai Chi Chan et al. demonstrate that the PMF plays a key role in starvation-induced antibiotic tolerance in E. c
Externí odkaz:
https://doaj.org/article/8414b54986c941f29ad265435e846442
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Coexistence of oqxAB and aac(6′)-Ib-cr is often associated with the expression of fluoroquinolone resistance in Salmonella. The actual role of the plasmid-borne oqxAB gene and its regulatory mechanism compared to its chromosomally encoded
Externí odkaz:
https://doaj.org/article/d45ebf4338364a888873b00053ed3829
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Acinetobacter baumannii is an important clinical pathogen which often causes fatal infections among seriously ill patients. Treatment options for managing infections caused by this organism have become limited as a result of emergence of carbapenem r
Externí odkaz:
https://doaj.org/article/daa6a17f683a4c7abf00fe8c88256c7e
Autor:
Jiachi Chiou, Qipeng Cheng, Perry Tim-fat Shum, Marcus Ho-yin Wong, Edward Wai-chi Chan, Sheng Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11480 (2021)
Class D β-lactamase OXA-48 is widely distributed among Gram-negative bacteria and is an important determinant of resistance to the last-resort carbapenems. Nevertheless, the detailed mechanism by which this β-lactamase hydrolyzes its substrates rem
Externí odkaz:
https://doaj.org/article/f47b3272ce3a49a29acb1e096c33c58c
Autor:
Marcus Ho-yin Wong, Miaomiao Xie, Liqi Xie, Dachuan Lin, Ruichao Li, Yuanjie Zhou, Edward Wai-Chi Chan, Sheng Chen
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
This study reports the complete sequence of pE80, a conjugative IncFII plasmid recovered from an E. coli strain isolated from chicken meat. This plasmid harbors multiple resistance determinants including oqxAB, fosA3, blaCTX-M-55 and blaTEM-1, and is
Externí odkaz:
https://doaj.org/article/02b86e3902c54bb78c7a628641195ed1
Autor:
Qipeng Cheng, Edward Wai-Chi Chan, Sheng Chen, Marcus Ho Yin Wong, Perry Tim-Fat Shum, Jiachi Chiou
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11480, p 11480 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11480, p 11480 (2021)
Class D β-lactamase OXA-48 is widely distributed among Gram-negative bacteria and is an important determinant of resistance to the last-resort carbapenems. Nevertheless, the detailed mechanism by which this β-lactamase hydrolyzes its substrates rem
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
The functional relationship between carbapenemase production and phenotypic resistance in Gram negative bacterial pathogens is often ill-defined. To address this issue, we developed a two-tiered Modified Hodge Test (MHT) approach for carbapenemase de
Externí odkaz:
https://doaj.org/article/bcacd83e964f4ab1adcaac98149874bb
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Recent evidence suggests that metabolic shutdown alone does not fully explain how bacteria exhibit phenotypic antibiotic tolerance. In an attempt to investigate the range of starvation-induced physiological responses underlying tolerance development,
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology
Frontiers in Microbiology
Acinetobacter baumannii is an important clinical pathogen which often causes fatal infections among seriously ill patients. Treatment options for managing infections caused by this organism have become limited as a result of emergence of carbapenem r
Publikováno v:
Journal of Antimicrobial Chemotherapy. 72:2750-2754
Objectives To characterize a novel virulence-resistance plasmid pSE380T carried by a Salmonella enterica serotype Enteritidis clinical strain SE380. Methods The plasmid pSE380T was conjugated to Escherichia coli strain J53 and sequenced by PacBio RSI