Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Marcus Henricsson"'
Autor:
Annika Wahlström, Ariel Brumbaugh, Wilhelm Sjöland, Lisa Olsson, Hao Wu, Marcus Henricsson, Annika Lundqvist, Kassem Makki, Stanley L. Hazen, Göran Bergström, Hanns-Ulrich Marschall, Michael A. Fischbach, Fredrik Bäckhed
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Alterations in gut microbiota composition are suggested to contribute to cardiometabolic diseases, in part by producing bioactive molecules. Some of the metabolites are produced by very low abundant bacterial taxa, which largely have been ne
Externí odkaz:
https://doaj.org/article/7c3061f41e2741e1be79161e6894712b
Autor:
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The cellular membrane in male meiotic germ cells contains a unique class of phospholipids and sphingolipids that is required for male reproduction. Here, we show that a conserved membrane fluidity sensor, AdipoR2, regulates the meiosis-speci
Externí odkaz:
https://doaj.org/article/4db1054da05548adae43cd8b6f7c67cf
Autor:
Annika Wahlström, Ömrüm Aydin, Lisa M. Olsson, Wilhelm Sjöland, Marcus Henricsson, Annika Lundqvist, Hanns-Ulrich Marschall, Rutger Franken, Arnold van de Laar, Victor Gerdes, Abraham S. Meijnikman, Dag Hofsø, Albert K. Groen, Jøran Hjelmesæth, Max Nieuwdorp, Fredrik Bäckhed
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105265- (2024)
Summary: Background: Bariatric surgery is an effective treatment option for obesity and provides long-term weight loss and positive effects on metabolism, but the underlying mechanisms are poorly understood. Alterations in bile acid metabolism have b
Externí odkaz:
https://doaj.org/article/64840ca30a314f63b2613355386bee20
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114132- (2024)
Summary: Insulin-PI3K signaling controls insulin secretion. Understanding this feedback mechanism is crucial for comprehending how insulin functions. However, the role of adipocyte insulin-PI3K signaling in controlling insulin secretion in vivo remai
Externí odkaz:
https://doaj.org/article/3dbafa545ff34e0d8fa05f80be9e0922
Autor:
Mario Ruiz, Ranjan Devkota, Dimitra Panagaki, Per-Olof Bergh, Delaney Kaper, Marcus Henricsson, Ali Nik, Kasparas Petkevicius, Johanna L. Höög, Mohammad Bohlooly-Y, Peter Carlsson, Jan Borén, Marc Pilon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Cells and organisms requires proper membrane composition, which the cell must modulate as membrane lipids are primary acquired from the diet. Here, Ruiz et al. identify a conserved pathway connecting the fluidity regulators AdipoR1/2 with fatty acid
Externí odkaz:
https://doaj.org/article/bf10f952953b4afda5ebc346e710e1c3
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Diabetic kidney disease is a consequence of hyperglycemia and other complex events driven by early glomerular hemodynamic changes and a progressive expansion of the mesangium. The molecular mechanisms behind the pathophysiological alteration
Externí odkaz:
https://doaj.org/article/2368e7d97a2b4e1eb4aa7850202b1061
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background AdipoR1 and AdipoR2 (AdipoRs) are plasma membrane proteins often considered to act as adiponectin receptors with a ceramidase activity. Additionally, the AdipoRs and their yeast and C. elegans orthologs are emerging as membrane ho
Externí odkaz:
https://doaj.org/article/1dbea79459594cb3a39f9c736f23b903
Autor:
Anwar Ali, Björn Redfors, Jessica Alkhoury, Jonatan Oras, Marcus Henricsson, Jan Boren, Elias Björnson, Aaron Espinosa, Malin Levin, Li‐Ming Gan, Elmir Omerovic
Publikováno v:
ESC Heart Failure, Vol 8, Iss 5, Pp 4130-4138 (2021)
Abstract Aims Takotsubo syndrome (TTS) is an acute potentially reversible cardiac syndrome characterized by variable regional myocardial akinesia that cannot be attributed to a culprit coronary artery occlusion. TTS is an important differential diagn
Externí odkaz:
https://doaj.org/article/a0476fe931184582a69f393cf4554398
Autor:
Veronika Voronova, Victor Sokolov, Yannick Morias, Malin Jonsson Boezelman, Maria Wågberg, Marcus Henricsson, Karl Hansson, Alexey Goltsov, Kirill Peskov, Monika Sundqvist
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Abnormal branched-chained amino acids (BCAA) accumulation in cardiomyocytes is associated with cardiac remodeling in heart failure. Administration of branched-chain α-keto acid dehydrogenase (BCKD) kinase inhibitor BT2 has been shown to
Externí odkaz:
https://doaj.org/article/c4ffbcea717249be8d4a464543d8c06f
Autor:
Peder Rustøen Braadland, Kai Markus Schneider, Annika Bergquist, Antonio Molinaro, Anita Lövgren-Sandblom, Marcus Henricsson, Tom Hemming Karlsen, Mette Vesterhus, Christian Trautwein, Johannes Roksund Hov, Hanns-Ulrich Marschall
Publikováno v:
JHEP Reports, Vol 4, Iss 11, Pp 100561- (2022)
Background & Aims: Farnesoid X receptor (FXR) agonists and fibroblast growth factor 19 (FGF19) analogues suppress bile acid synthesis and are being investigated for their potential therapeutic efficacy in cholestatic liver diseases. We investigated w
Externí odkaz:
https://doaj.org/article/5da6d93d1b724ac6b4d7ca6c74b5971b