Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marcus H, Andrews"'
Autor:
Vincent L. Reynolds, Marcus H. Andrews
Publikováno v:
Translating Molecules into Medicines ISBN: 9783319500409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80399047f1eadd6a45f056264b6622dd
https://doi.org/10.1007/978-3-319-50042-3_8
https://doi.org/10.1007/978-3-319-50042-3_8
Publikováno v:
Endocrinology
Hypothalamo-pituitary-adrenal (HPA) axis activity is subject to negative feedback control by glucocorticoids. Although the rapid component of this feedback is widely considered to contribute to regulation of dynamic HPA activity, few in vivo data exi
Publikováno v:
Veterinary Ophthalmology. 15:183-187
Isolated ectopic brain tissue within the orbit is an extremely rare finding and has never been reported in dogs or other domestic species. In this case, a focal choristoma of ectopic grey matter-like tissue was present within the retina of a mature f
Autor:
Owen Chan, Mladen Vranic, Stephen G. Matthews, Karen Inouye, Qifu Li, Marcus H. Andrews, Jessica T.Y. Yue
Publikováno v:
Brain Research Bulletin. 77:149-157
We previously demonstrated that while diabetic animals receiving long-term insulin treatment exhibited some impairment in their corticosterone response to hypoglycemia, the stress response to hypoglycemia was completely absent when these animals were
Publikováno v:
The Journal of Physiology. 572:31-44
Prenatal stress (PS) and maternal exposure to exogenous glucocorticoids can lead to permanent modification of hypothalamo-pituitary-adrenal (HPA) function and stress-related behaviour. Both of these manipulations lead to increased fetal exposure to g
Autor:
William Gibb, Grazyna M. Kalabis, Stephen G. Matthews, Alice Kostaki, Marcus H. Andrews, Sophie Petropoulos
Publikováno v:
Biology of Reproduction. 73:591-597
The multidrug resistance phosphoglycoprotein ATP-binding cassette subfamily B (ABCB1) actively extrudes a range of structurally and functionally diverse xenobiotics as well as glucocorticoids. ABCB1 is present in many cancer cell types as well as in
Autor:
Umar Iqbal, Stephen G. Matthews, James F. Brien, James N. Reynolds, S. Banjanin, Marcus H. Andrews
Publikováno v:
Journal of Neuroendocrinology. 17:600-608
The present study tested the hypothesis that chronic prenatal ethanol exposure causes long-lasting changes in glucocorticoid signalling in postnatal offspring. Pregnant guinea pigs were treated with ethanol (4 g/kg maternal body weight/day), isocalor
Autor:
Christopher McCabe, Rania Lingas, Marcus H. Andrews, Jayne A. Franklyn, Mark D. Kilby, Stephen G. Matthews, Shiao Chan
Publikováno v:
The Journal of Physiology. 566:467-480
Thyroid hormone deprivation during fetal life has been implicated in neurodevelopmental morbidity. In humans, poor growth in utero is also associated with fetal hypothyroxinaemia. In guinea pigs, a short period (48 h) of maternal nutrient deprivation
Autor:
Alice Kostaki, Lucy McCabe, Elaine Setiawan, Stephen G. Matthews, Dawn Owen, Marcus H. Andrews
Publikováno v:
Endocrinology. 145:3796-3803
Steroid receptor coactivator (SRC) proteins interact with glucocorticoid receptors in a ligand-dependent manner to enhance transcription. Although glucocorticoids are essential for normal brain maturation, little is known about the presence or regula
Autor:
Dawn Owen, Marcus H. Andrews, Lucy McCabe, Elaine Setiawan, Alice Kostaki, S. Banjanin, Stephen G. Matthews
Publikováno v:
The Journal of Physiology. 555:659-670
Fetal exposure to excess glucocorticoids (GCs) programs the developing hypothalamo-pituitary-adrenal (HPA) axis, and may predispose offspring to adult-onset disease. During development, serotonin (5-HT) influences transcription of hippocampal GR mRNA