Zobrazeno 1 - 10
of 576
pro vyhledávání: '"Marcus Dörr"'
Autor:
Helena Bui, Amena Keshawarz, Mengyao Wang, Mikyeong Lee, Scott M. Ratliff, Lisha Lin, Kira S. Birditt, Jessica D. Faul, Annette Peters, Christian Gieger, Thomas Delerue, Sharon L. R. Kardia, Wei Zhao, Xiuqing Guo, Jie Yao, Jerome I. Rotter, Yi Li, Xue Liu, Dan Liu, Juliana F. Tavares, Gökhan Pehlivan, Monique M. B. Breteler, Irma Karabegovic, Carolina Ochoa-Rosales, Trudy Voortman, Mohsen Ghanbari, Joyce B. J. van Meurs, Mohamed Kamal Nasr, Marcus Dörr, Hans J. Grabe, Stephanie J. London, Alexander Teumer, Melanie Waldenberger, David R. Weir, Jennifer A. Smith, Daniel Levy, Jiantao Ma, Chunyu Liu
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Epigenome‐wide association studies have identified multiple DNA methylation sites (CpGs) associated with alcohol consumption, an important lifestyle risk factor for cardiovascular diseases. This study aimed to test the hypothesi
Externí odkaz:
https://doaj.org/article/778cf18febfb469f98f4928da01f6554
Autor:
Fabian Frost, Stefan Weiss, Johannes Hertel, Malte Rühlemann, Corinna Bang, Andre Franke, Matthias Nauck, Marcus Dörr, Henry Völzke, Dirk Roggenbuck, Peter Schierack, Uwe Völker, Georg Homuth, Ali A. Aghdassi, Matthias Sendler, Markus M. Lerch, Frank U. Weiss
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Antimicrobial autoantigenic glycoprotein 2 (GP2) is an important component of the innate immune system which originates from the exocrine pancreas as well as from the small intestines. The relationship of GP2 with the intestinal m
Externí odkaz:
https://doaj.org/article/c58f07de2a2f40068a82097d56140e30
Distinct genetic liability profiles define clinically relevant patient strata across common diseases
Autor:
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T. Jiménez-Barrón, Till F. M. Andlauer, Moritz von Scheidt, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G. Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J. Ziller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract Stratified medicine holds great promise to tailor treatment to the needs of individual patients. While genetics holds great potential to aid patient stratification, it remains a major challenge to operationalize complex genetic risk factor p
Externí odkaz:
https://doaj.org/article/00e3ef22c51b4762863b27a5f510cabb
Autor:
Yvan Devaux, Lu Zhang, Andrew I. Lumley, Kanita Karaduzovic-Hadziabdic, Vincent Mooser, Simon Rousseau, Muhammad Shoaib, Venkata Satagopam, Muhamed Adilovic, Prashant Kumar Srivastava, Costanza Emanueli, Fabio Martelli, Simona Greco, Lina Badimon, Teresa Padro, Mitja Lustrek, Markus Scholz, Maciej Rosolowski, Marko Jordan, Timo Brandenburger, Bettina Benczik, Bence Agg, Peter Ferdinandy, Jörg Janne Vehreschild, Bettina Lorenz-Depiereux, Marcus Dörr, Oliver Witzke, Gabriel Sanchez, Seval Kul, Andy H. Baker, Guy Fagherazzi, Markus Ollert, Ryan Wereski, Nicholas L. Mills, Hüseyin Firat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Tools for predicting COVID-19 outcomes enable personalized healthcare, potentially easing the disease burden. This collaborative study by 15 institutions across Europe aimed to develop a machine learning model for predicting the risk of in-h
Externí odkaz:
https://doaj.org/article/54234423656547d89b595a58c9921da7
Autor:
William J. Young, Peter J. van der Most, Traci M. Bartz, Maxime M. Bos, Ginevra Biino, ThuyVy Duong, Luisa Foco, Jesus T. Lominchar, Martina Müller‐Nurasyid, Giuseppe Giovanni Nardone, Alessandro Pecori, Julia Ramirez, Linda Repetto, Katharina Schramm, Xia Shen, Stefan van Duijvenboden, Diana van Heemst, Stefan Weiss, Jie Yao, Jan‐Walter Benjamins, Alvaro Alonso, Beatrice Spedicati, Mary L. Biggs, Jennifer A. Brody, Marcus Dörr, Christian Fuchsberger, Martin Gögele, Xiuqing Guo, M. Arfan Ikram, J. Wouter Jukema, Stefan Kääb, Jørgen K. Kanters, Henry J. Lin, Allan Linneberg, Matthias Nauck, Ilja M. Nolte, Giulia Pianigiani, Aurora Santin, Elsayed Z. Soliman, Paola Tesolin, Simona Vaccargiu, Melanie Waldenberger, Pim van der Harst, Niek Verweij, Dan E. Arking, Maria Pina Concas, Alessandro De Grandi, Giorgia Girotto, Niels Grarup, Maryam Kavousi, Dennis O. Mook‐Kanamori, Pau Navarro, Michele Orini, Sandosh Padmanabhan, Cristian Pattaro, Annette Peters, Mario Pirastu, Peter P. Pramstaller, Susan R. Heckbert, Mortiz Sinner, Harold Snieder, Uwe Völker, James F. Wilson, W. James Gauderman, Pier D. Lambiase, Nona Sotoodehnia, Andrew Tinker, Helen R. Warren, Raymond Noordam, Patricia B. Munroe
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background Ventricular repolarization time (ECG QT and JT intervals) is associated with malignant arrhythmia. Genome‐wide association studies have identified 230 independent loci for QT and JT; however, 50% of their heritability remains unexplained
Externí odkaz:
https://doaj.org/article/d9db835045cc4f1b993097b3854693a3
Autor:
Maximilian Dietzmann, Dörte Radke, Marcello RP Markus, Mats Wiese, Henry Völzke, Stephan B. Felix, Marcus Dörr, Martin Bahls, Till Ittermann
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Low relative fat free mass (FFM) is associated with a greater risk of chronic diseases and mortality. Unfortunately, FFM is currently not being measured regularly to allow for individuals therapy. Objective One reason why FFM is n
Externí odkaz:
https://doaj.org/article/11925a8da6464dbc9bdead04f3ed4801
Autor:
Andrea Weber, Vincent T. van Hees, Michael J. Stein, Sylvia Gastell, Karen Steindorf, Florian Herbolsheimer, Stefan Ostrzinski, Tobias Pischon, Mirko Brandes, Lilian Krist, Michael Marschollek, Karin Halina Greiser, Katharina Nimptsch, Berit Brandes, Carmen Jochem, Anja M. Sedlmeier, Klaus Berger, Hermann Brenner, Christoph Buck, Stefanie Castell, Marcus Dörr, Carina Emmel, Beate Fischer, Claudia Flexeder, Volker Harth, Antje Hebestreit, Jana-Kristin Heise, Bernd Holleczek, Thomas Keil, Lena Koch-Gallenkamp, Wolfgang Lieb, Claudia Meinke-Franze, Karin B. Michels, Rafael Mikolajczyk, Alexander Kluttig, Nadia Obi, Annette Peters, Börge Schmidt, Sabine Schipf, Matthias B. Schulze, Henning Teismann, Sabina Waniek, Stefan N. Willich, Michael F. Leitzmann, Hansjörg Baurecht
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Large population-based cohort studies utilizing device-based measures of physical activity are crucial to close important research gaps regarding the potential protective effects of physical activity on chronic diseases. The present study de
Externí odkaz:
https://doaj.org/article/dee20163ca0f46aa9a4e6758800f77ea
Autor:
Adrian Richter, Julia Truthmann, Eva Hummers, Julia Freyer Martins Pereira, Ildikó Gágyor, Franziska Schuster, Amelie Witte, Susanne Böhm, Alexandra Greser, Petra Kamin, Sylvia Stracke, Marcus Dörr, Robin Bülow, Stefan Engeli, Jean François Chenot, Till Ittermann
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background To date, colchicine and prednisolone are two effective therapies for the treatment of acute gout but have never been compared directly in a randomized clinical trial. In addition, in previous trials of treating acute gout patients
Externí odkaz:
https://doaj.org/article/6db7793cdf5f420ea855b671b7d89128
Autor:
Till Ittermann, Sabine Kaczmarek, Anne Obst, Raik Könemann, Martin Bahls, Marcus Dörr, Beate Stubbe, Alexander Heine, Dirk Habedank, Ralf Ewert
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Recently, the parameter internal work (IW) has been introduced as change in oxygen uptake (VO2) between resting and unloading workload in cardiopulmonary exercise testing (CPET). The proportional IW (PIW) was defined as IW divided by VO2 at
Externí odkaz:
https://doaj.org/article/63bd9cc212ba42329744dd7f7490a93d
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Recent studies have highlighted the role of low-grade systemic inflammation in linking periodontitis to cardiovascular disease (CVD) outcomes, but many aspects remain unclear. This study examines the independent and reciprocal ass
Externí odkaz:
https://doaj.org/article/b8843787a43342a1ba8aaaa529cfe0b2