Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marcus Daniels"'
Autor:
S Gnanakaran, Tanmoy Bhattacharya, Marcus Daniels, Brandon F Keele, Peter T Hraber, Alan S Lapedes, Tongye Shen, Brian Gaschen, Mohan Krishnamoorthy, Hui Li, Julie M Decker, Jesus F Salazar-Gonzalez, Shuyi Wang, Chunlai Jiang, Feng Gao, Ronald Swanstrom, Jeffrey A Anderson, Li-Hua Ping, Myron S Cohen, Martin Markowitz, Paul A Goepfert, Michael S Saag, Joseph J Eron, Charles B Hicks, William A Blattner, Georgia D Tomaras, Mohammed Asmal, Norman L Letvin, Peter B Gilbert, Allan C Decamp, Craig A Magaret, William R Schief, Yih-En Andrew Ban, Ming Zhang, Kelly A Soderberg, Joseph G Sodroski, Barton F Haynes, George M Shaw, Beatrice H Hahn, Bette Korber
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002209 (2011)
Here we have identified HIV-1 B clade Envelope (Env) amino acid signatures from early in infection that may be favored at transmission, as well as patterns of recurrent mutation in chronic infection that may reflect common pathways of immune evasion.
Externí odkaz:
https://doaj.org/article/22d53c62f6de46ae98a1717e386d0e84
Autor:
Mohammed Asmal, Ina Hellmann, Weimin Liu, Brandon F Keele, Alan S Perelson, Tanmoy Bhattacharya, S Gnanakaran, Marcus Daniels, Barton F Haynes, Bette T Korber, Beatrice H Hahn, George M Shaw, Norman L Letvin
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23673 (2011)
Mucosal transmission of the human immunodeficiency virus (HIV) results in a bottleneck in viral genetic diversity. Gnanakaran and colleagues used a computational strategy to identify signature amino acids at particular positions in Envelope that were
Externí odkaz:
https://doaj.org/article/fd8dcedb49ad4da585d28f0c6e8aa261
Autor:
Natasha Wood, Tanmoy Bhattacharya, Brandon F Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, Guido Ferrari, Barton F Haynes, Andrew McMichael, George M Shaw, Beatrice H Hahn, Bette Korber, Cathal Seoighe
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000414 (2009)
The pattern of viral diversification in newly infected individuals provides information about the host environment and immune responses typically experienced by the newly transmitted virus. For example, sites that tend to evolve rapidly across multip
Externí odkaz:
https://doaj.org/article/c6f2e06182a4420c90b35798d349c77e
Autor:
Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S. G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P. Richard Harrigan
Publikováno v:
PLoS Pathogens, Vol 3, Iss 8 (2007)
Externí odkaz:
https://doaj.org/article/cfd16983220b4d1e8f0efeed89e7df00
Autor:
Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan
Publikováno v:
PLoS Pathogens, Vol 3, Iss 7, p e94 (2007)
Despite the formidable mutational capacity and sequence diversity of HIV-1, evidence suggests that viral evolution in response to specific selective pressures follows generally predictable mutational pathways. Population-based analyses of clinically
Externí odkaz:
https://doaj.org/article/19de9ceb19fb40818ab5ac1b57c7dd0d
Autor:
Jonas Mattisson, Jonatan Halvardson, Hanna Davies, Bożena Bruhn-Olszewska, Paweł Olszewski, Marcus Danielsson, Josefin Bjurling, Amanda Lindberg, Ammar Zaghlool, Edyta Rychlicka-Buniowska, Jan P. Dumanski, Lars A. Forsberg
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. It h
Externí odkaz:
https://doaj.org/article/3fb79618f8b24d1694b937e0dfc03697
Autor:
Chigusa Kobayashi, Wataru Nishima, Anna Lappala, Will Fischer, Marcus Daniels, Jaewoon Jung, Tamar Schlick, Karissa Y. Sanbonmatsu, Dominic Phillips, Gavin D. Bascom, Yuji Sugita, Chang-Shung Tung, Adetokunbo Adedoyin, Michael E. Wall
Publikováno v:
J Comput Chem
The growing interest in the complexity of biological interactions is continuously driving the need to increase system size in biophysical simulations, requiring not only powerful and advanced hardware but adaptable software that can accommodate a lar
Autor:
Mark Muldoon, Marcus Daniels, Jennifer L. Kirchherr, Webster Kasongo, Jennifer Hamilton, Xing Yuan, Rosemary Musonda, Barton F. Haynes, Xiaozhi Lu, Feng Gao, Victor Chalwe, David C. Montefiori, Lawrence Mwananyanda, Chanda Mulenga, Sandrasegaram Gnanakaran, Bette T. Korber
Publikováno v:
Kirchherr, J L, Hamilton, J, Lu, X, Gnanakaran, S, Muldoon, M, Daniels, M, Kasongo, W, Chalwe, V, Mulenga, C, Mwananyanda, L, Musonda, R M, Yuan, X, Montefiori, D C, Korber, B T, Haynes, B F & Gao, F 2011, ' Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120 ', Virology, vol. 409, no. 2, pp. 163-174 . https://doi.org/10.1016/j.virol.2010.09.031
Neutralizing antibodies (Nabs) are thought to play an important role in prevention and control of HIV-1 infection and should be targeted by an AIDS vaccine. It is critical to understand how HIV-1 induces Nabs by analyzing viral sequences in both test
Autor:
Ishita Rahman, Peter T. Hraber, Michael S. Seaman, Bette T. Korber, Wendy W. Yeh, Svetlana Miljkovic, George M. Shaw, Mohammed Asmal, James B. Whitney, Brandon F. Keele, Marcus Daniels, Norman L. Letvin, Daiva Nevidomskyte, Ayush Giri, Beatrice H. Hahn, Rory Coffey
Publikováno v:
Journal of Virology. 84:6018-6032
While neutralizing antibodies (Nabs) mediate protection in humans against a diversity of viral pathogens (38, 53, 72), it is unclear how they impact human immunodeficiency virus type 1 (HIV-1) infection. One reason that the contribution of neutralizi
Autor:
William J. Bruno, Marcus Daniels, Moulik Kothari, Bette T. Korber, Carla Kuiken, Ruy M. Ribeiro, Thomas Leitner, Gayathri Athreya, Irina Maljkovic Berry
Publikováno v:
Epidemics. 1(4):230-239
Large-sequence datasets provide an opportunity to investigate the dynamics of pathogen epidemics. Thus, a fast method to estimate the evolutionary rate from large and numerous phylogenetic trees becomes necessary. Based on minimizing tip height varia