Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marcus D. Tuttle"'
Autor:
Mikhail A, Kostylev, Marcus D, Tuttle, Suho, Lee, Lauren E, Klein, Hideyuki, Takahashi, Timothy O, Cox, Erik C, Gunther, Kurt W, Zilm, Stephen M, Strittmatter
Publikováno v:
Molecular cell. 72(3)
Protein phase separation by low complexity, intrinsically disordered domains generates membraneless organelles and links to neurodegeneration. Cellular prion protein (PrP(C)) contains such domains, causes spongiform degeneration and is a receptor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59bdf1d83fd77c85506f509141a96ca1
https://pubmed.ncbi.nlm.nih.gov/30401430
https://pubmed.ncbi.nlm.nih.gov/30401430
Autor:
Chad M. Rienstra, Deborah A. Berthold, Thomas Insley, Petr Král, Wayne Lin, Catherine J. Murphy, Lingyang Zhu, Marcus D. Tuttle
Publikováno v:
The Journal of Physical Chemistry C. 119:21035-21043
Gold nanoparticles (Au NPs) have attracted much attention due to their potential applications in nano-medicine. While numerous studies have quantified biomolecular adsorption to Au NPs in terms of equilibrium binding constants, far less is known abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b74c799716760fea4f718434e3bb86
https://doi.org/10.1021/acs.jpcc.5b07701
https://doi.org/10.1021/acs.jpcc.5b07701
Publikováno v:
Methods in Molecular Biology ISBN: 9781493929771
Solid-state NMR spectroscopy (SSNMR) is an established and invaluable tool for the study of amyloid fibril structure with atomic-level detail. Optimization of the homogeneity and concentration of fibrils enhances the resolution and sensitivity of SSN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fff9fe9f4e0d8185a643b32ad8b4f07
https://doi.org/10.1007/978-1-4939-2978-8_11
https://doi.org/10.1007/978-1-4939-2978-8_11
Autor:
Timothy O. Cox, Stephen M. Strittmatter, Suho Lee, Lauren E. Klein, Kurt W. Zilm, Hideyuki Takahashi, Mikhail A. Kostylev, Erik C. Gunther, Marcus D. Tuttle
Publikováno v:
Molecular Cell. 72:426-443.e12
Protein phase separation by low-complexity, intrinsically disordered domains generates membraneless organelles and links to neurodegeneration. Cellular prion protein (PrPC) contains such domains, causes spongiform degeneration, and is a receptor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ff8c5390eaec25506bd233dc155ae7
https://doi.org/10.1016/j.molcel.2018.10.009
https://doi.org/10.1016/j.molcel.2018.10.009
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1345
Solid-state NMR spectroscopy (SSNMR) is an established and invaluable tool for the study of amyloid fibril structure with atomic-level detail. Optimization of the homogeneity and concentration of fibrils enhances the resolution and sensitivity of SSN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b1cf4bf101842607eb6dff28129b88f
https://pubmed.ncbi.nlm.nih.gov/26453212
https://pubmed.ncbi.nlm.nih.gov/26453212
Autor:
Amy Kendall, Joseph M. Courtney, Marcus D. Tuttle, Gemma Comellas, Jae K Kim, Charles D. Schwieters, Kathryn D. Kloepper, William Wan, Chad M. Rienstra, Gerald Stubbs, Alexander M. Barclay, Virginia M.-Y. Lee, Jimin George, Andrew J. Nieuwkoop, Dustin J. Covell, Deborah A. Berthold
Publikováno v:
Nature structural & molecular biology
Misfolded α-synuclein amyloid fibrils are the principal components of Lewy bodies and neurites, hallmarks of Parkinson's disease (PD). We present a high-resolution structure of an α-synuclein fibril, in a form that induces robust pathology in prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f665dd92fd86642b9319246b2d6829ba
https://pubmed.ncbi.nlm.nih.gov/27018801
https://pubmed.ncbi.nlm.nih.gov/27018801
Autor:
Mary C. Clay, Grant S. Hisao, Martin D. Burke, Erin L Wildeman, Thomas Anderson, Marcus D. Tuttle, Chad M. Rienstra, Alexander G. Cioffi, Tamir Gonen, Nashrah Maryum, Brice E. Uno, Shu Wang, Gemma Comellas, Andrew J. Nieuwkoop, Katrina A. Diaz
Publikováno v:
Nature chemical biology, vol 10, iss 5
For over 50 years, amphotericin has remained the powerful but highly toxic last line of defense in treating life-threatening fungal infections in humans with minimal development of microbial resistance. Understanding how this small molecule kills yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f930ecc142cc83bef3e1c3add93b50
https://pubmed.ncbi.nlm.nih.gov/24747527
https://pubmed.ncbi.nlm.nih.gov/24747527
Autor:
Qing Ye, Joseph R. Peterson, Ming Tang, Marcus D. Tuttle, Joseph M. Courtney, Eric D. Watt, Anna E. Nesbitt, Kristin M. Nuzzio, Lindsay J. Sperling, James H. Morrissey, Chad M. Rienstra, Gemma Comellas
Publikováno v:
Structure. (10):1958-1966
SummaryStandard methods for de novo protein structure determination by nuclear magnetic resonance (NMR) require time-consuming data collection and interpretation efforts. Here we present a qualitatively distinct and novel approach, called Comparative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63772d6d5f25a4ce41b6fe6d8ac9e6ca