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pro vyhledávání: '"Marcus D. Kelly"'
Autor:
Marcus D. Kelly, Matthew R. Pawlak, Kevin H. Zhan, Ghaidan A. Shamsan, Wendy R. Gordon, David J. Odde
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036102-036102-11 (2024)
Cell migration is the major driver of invasion and metastasis during cancer progression. For cells to migrate, they utilize the actin–myosin cytoskeleton and adhesion molecules, such as integrins and CD44, to generate traction forces in their envir
Externí odkaz:
https://doaj.org/article/1e07d54b25c34fafa4f2d643b0677027
Autor:
Matthew R. Pawlak, Adam T. Smiley, Maria Paz Ramirez, Marcus D. Kelly, Ghaidan A. Shamsan, Sarah M. Anderson, Branden A. Smeester, David A. Largaespada, David J. Odde, Wendy R. Gordon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Mechanical forces drive critical cellular processes that are reflected in mechanical phenotypes, or mechanotypes, of cells and their microenvironment. We present here “Rupture And Deliver” Tension Gauge Tethers (RAD-TGTs) in which flow c
Externí odkaz:
https://doaj.org/article/1fd6216c1397488692642b2a66cb4e0c
Autor:
Matthew R. Pawlak, Adam T. Smiley, Marcus D. Kelly, Ghaidan A. Shamsan, Sarah M. Anderson, Branden A. Smeester, David A. Largaespada, David J. Odde, Wendy R. Gordon
Mechanical force is a key driver of cellular processes and is dysregulated in many diseases. Measuring cellular tensions to elucidate mechanotransduction pathways typically involves high-resolution but low throughput imaging of surfaces and arduous e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46cbef743bf47cb12a9a4d77309c293d
https://doi.org/10.1101/2022.11.08.515662
https://doi.org/10.1101/2022.11.08.515662
Autor:
Marcus D. Kelly
Publikováno v:
Biophysical Journal. 122:264a-265a
Autor:
Maria Paz Ramirez, Michael J. M. Anderson, Marcus D. Kelly, Lauren J. Sundby, Anthony R. Hagerty, Sophia J. Wenthe, David J. Odde, James M. Ervasti, Wendy R. Gordon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(25)
Dystrophin is an essential muscle protein that contributes to cell membrane stability by mechanically linking the actin cytoskeleton to the extracellular matrix via an adhesion complex called the dystrophin–glycoprotein complex. The absence or impa