Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Marcus D. Atlas"'
Autor:
Elaine Y.M. Wong, Xin E. Khoh, Shang-Chih Chen, Joey Lye, Fiona K. Leith, Dan Zhang, Tina M. Lamey, Jennifer A. Thompson, Terri L. McLaren, Marcus D. Atlas, Fred K. Chen, Samuel McLenachan
Publikováno v:
Stem Cell Research, Vol 79, Iss , Pp 103492- (2024)
Usher syndrome (USH) is the most common cause of inherited deaf-blindness. Here, we produced the LEIi020-A and LEIi020-B induced pluripotent stem cell (iPSC) lines from dermal fibroblasts derived from a patient with USH1B caused by inheritance of hom
Externí odkaz:
https://doaj.org/article/d973400b1fc549acb8e519812dc07c06
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Despite significant advances in the development of therapeutics for hearing loss, drug delivery to the middle and inner ear remains a challenge. As conventional oral or intravascular administration are ineffective due to poor bioavailability and impe
Externí odkaz:
https://doaj.org/article/91833ae8757548e38797c3240e29e1aa
Autor:
Kady J. Braack, Tylah Miles, Farah Amat, Daniel J. Brown, Marcus D. Atlas, Jafri Kuthubutheen, Wilhelmina H.A.M. Mulders, Cecilia M. Prêle
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19343- (2023)
Cochlear implants (CIs) allow individuals with profound hearing loss to understand speech and perceive sounds. However, not all patients obtain the full benefits that CIs can provide and the cause of this disparity is not fully understood. One possib
Externí odkaz:
https://doaj.org/article/084def3e33214542abbbf76eb1c3397d
Autor:
Joey Lye, Derek S. Delaney, Fiona K. Leith, Varda S. Sardesai, Samuel McLenachan, Fred K. Chen, Marcus D. Atlas, Elaine Y. M. Wong
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3347 (2023)
Up to 1.5 billion people worldwide suffer from various forms of hearing loss, with an additional 1.1 billion people at risk from various insults such as increased consumption of recreational noise-emitting devices and ageing. The most common type of
Externí odkaz:
https://doaj.org/article/67c4483bde4d4591ad7fb3de626eb34b
Autor:
Dona M. P. Jayakody, Osvaldo P. Almeida, Andrew H. Ford, Marcus D. Atlas, Nicola T. Lautenschlager, Peter L. Friedland, Suzanne Robinson, Marshall Makate, Lize Coetzee, Angela S. P. Liew, Leon Flicker
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Globally, about 50 million people were living with dementia in 2015, with this number projected to triple by 2050. With no cure or effective treatment currently insight, it is vital that factors are identified which will help prev
Externí odkaz:
https://doaj.org/article/c5bead46183c43dcabbe3934cb1282d9
Autor:
Khine Zaw, Elaine Y.M. Wong, Xiao Zhang, Dan Zhang, Shang-Chih Chen, Jennifer A. Thompson, Tina Lamey, Terri McLaren, John N. De Roach, Steve D. Wilton, Sue Fletcher, Chalermchai Mitrpant, Marcus D. Atlas, Fred K. Chen, Samuel McLenachan
Publikováno v:
Stem Cell Research, Vol 50, Iss , Pp 102129- (2021)
Mutations in the USH2A gene are the most common cause of Usher syndrome and autosomal recessive non-syndromic retinitis pigmentosa. Here, we describe the generation of three induced pluripotent stem cell lines from dermal fibroblasts derived from a p
Externí odkaz:
https://doaj.org/article/fdcbe990f7584afa82d8c62ab5a4741b
Autor:
Meg Whatley, Abbie Francis, Zi Ying Ng, Xin Ee Khoh, Marcus D. Atlas, Rodney J. Dilley, Elaine Y. M. Wong
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Usher syndrome (USH) is an autosomal recessive (AR) disorder that permanently and severely affects the senses of hearing, vision, and balance. Three clinically distinct types of USH have been identified, decreasing in severity from Type 1 to 3, with
Externí odkaz:
https://doaj.org/article/b250574c6edf428b8e53dc3d70097629
Autor:
Armin Mooranian, Melissa Jones, Daniel Walker, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Hani Al-Salami
Publikováno v:
Nanomaterials, Vol 12, Iss 4, p 647 (2022)
Bile acids (BA)s are known surfactants and well-documented to play a major role in food digestion and absorption. Recently, potential endocrinological and formulation-stabilisation effects of BAs have been explored and their pharmacological effects o
Externí odkaz:
https://doaj.org/article/a345f24a9c93499ebc4322aacdde9a68
Autor:
Armin Mooranian, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Hani Al-Salami
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 73 (2022)
Recent studies in our laboratories have shown promising effects of bile acids in ➀ drug encapsulation for oral targeted delivery (via capsule stabilization) particularly when encapsulated with Eudragit NM30D® and ➁ viable-cell encapsulation and
Externí odkaz:
https://doaj.org/article/729f3ec7baed47fb98fe1400c7898c51
Autor:
Melissa Jones, Corina Mihaela Ionescu, Daniel Walker, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Armin Mooranian, Hani Al-Salami
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 836 (2022)
Biguanides, particularly the widely prescribed drug metformin, have been marketed for many decades and have well-established absorption profiles. They are commonly administered via the oral route and, despite variation in oral uptake, remain commonly
Externí odkaz:
https://doaj.org/article/8bbb6c31e85d4397a7ccfb68c50963e5