Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marcus D, Darrabie"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 1, Pp 353-360 (2015)
Background: Creatine, Phosphocreatine, and creatine kinases, constitute an energy shuttle that links ATP production in mitochondria with cellular consumption sites. Myocytes and neurons cannot synthesize creatine and depend on uptake across the cell
Externí odkaz:
https://doaj.org/article/d6c087a462f24c039ac5d80420db34ac
Autor:
Alicia M. Mohr, Scott C. Brakenridge, Marcus D. Darrabie, Martin A. Rosenthal, Nicole R. Mercier, R. Stephen Smith, Frederick A. Moore, Chasen A. Croft
Publikováno v:
Journal of the American College of Surgeons. 227:127-133
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a novel method of controlling subdiaphragmatic hemorrhage while improving hemodynamic stability. This procedure achieves many of the goals of resuscitative thoracotomy (R
Publikováno v:
The American Surgeon. 85:176-178
Publikováno v:
The American surgeon. 85(3)
Autor:
Jennifer Cheeseman, Eric A. Elster, Alexander T. Limkakeng, Allan D. Kirk, Bruce A. Sullenger, Marcus D. Darrabie, Jaewoo Lee, Joseph B. Borawski
Publikováno v:
The Journal of surgical research. 231
Surgical insult and trauma have been shown to cause dysregulation of the immune and inflammatory responses. Interaction of damage-associated molecular patterns (DAMPs) with toll-like receptors (TLRs) initiates innate immune response and systemic infl
Autor:
Dawn E. Bowles, Rebecca M. Baron, Lucia Santacruz, Rajashree Mishra, Danny O. Jacobs, Marcus D. Darrabie, Jose G. Mantilla, Antonio J. Arciniegas
Publikováno v:
Physiological Reports
Creatine (Cr), phosphocreatine (PCr), and creatine kinases (CK) comprise an energy shuttle linking ATP production in mitochondria with cellular consumption sites. Myocytes cannot synthesize Cr: these cells depend on uptake across the cell membrane by
Autor:
Marcus D. Darrabie, Bryan J. Feger, Rajashree Mishra, Danny O. Jacobs, Lucia Santacruz, Jose G. Mantilla
Publikováno v:
Cardiovascular Toxicology. 15:180-188
Heart failure is a common complication of doxorubicin (DOX) therapy. Previous studies have shown that DOX adversely impacts cardiac energy metabolism, and the ensuing energy deficiencies antedate clinical manifestations of cardiac toxicity. Brief exp
Autor:
George Z. Li, Ryan S. Turley, Rebekah R. White, Paul J. Speicher, Michael E. Lidsky, John E. Scarborough, Bryan M. Clary, Marcus D. Darrabie
Publikováno v:
Journal of the American College of Surgeons. 218:827-834
Despite the rising incidence of hepatocellular carcinoma (HCC), challenges and controversy persist in optimizing treatment. As recent randomized trials suggest that ablation can have oncologic equivalence compared with resection for early HCC, the re
Autor:
Miguel Pinilla Vera, Danny O. Jacobs, Antonio J. Arciniegas, Rajashree Mishra, Lucia Santacruz, Marcus D. Darrabie, Jose G. Mantilla
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H539-H548
Doxorubicin is commonly used to treat leukemia, lymphomas, and solid tumors, such as soft tissue sarcomas or breast cancer. A major side effect of doxorubicin therapy is dose-dependent cardiotoxicity. Doxorubicin's effects on cardiac energy metabolis
Autor:
Danny O. Jacobs, Dawn E. Bowles, Lucia Santacruz, Marcus D. Darrabie, Antonio J. Arciniegas, Rajashree Mishra
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 300:E870-E876
Profound alterations in myocellular creatine and phosphocreatine levels are observed during human heart failure. To maintain its intracellular creatine stores, cardiomyocytes depend upon a cell membrane creatine transporter whose regulation is not cl