Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marcus Caine"'
Autor:
Matthew R. Dreher, Pedro Garcia, Sean L. Willis, Andrew L. Lewis, Shuning Bian, Daniel F. Daly, Marcus Caine, Alexander Henman, Yiqing Tang, Robert Carlisle, Eleanor Stride
Understanding the intra-tumoral distribution of chemotherapeutic drugs is extremely important in predicting therapeutic outcome. Tissue mimicking gel phantoms are useful for studying drug distribution in vitro but quantifying distribution is laboriou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a906a92ac6820943611763ad2c821ea
https://doi.org/10.1016/j.ejps.2021.105772
https://doi.org/10.1016/j.ejps.2021.105772
Autor:
Z. A. Bascal, Andrew L. Lewis, Matthew R. Dreher, Yiqing Tang, Thierry de Baere, Ting Chung, Hugh Kilpatrick, Sean L. Willis, Marcus Caine
Publikováno v:
Theranostics
There are currently two methods widely used in clinical practice to perform transarterial chemoembolization (TACE). One is based on mixing an aqueous drug with an iodized oil (Lipiodol) and creating an emulsion that is delivered intraarterially, foll
Autor:
Andrew L. Lewis, Z. A. Bascal, Yiqing Tang, Lorcan Hinchcliffe, Hugh Kilpatrick, Pedro Garcia, Sean L. Willis, Koorosh Ashrafi, Marcus Caine, Wei Guo
Publikováno v:
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
The in vitro and in vivo handling and performance characteristics of a small caliber radiopaque embolic microsphere, 40–90 μm DC Bead LUMI™ (LUMI40‐90), were studied. Microsphere drug loading and elution and effects on size, suspension, and mi
Autor:
Wei Guo, Koorosh Ashrafi, Rosemary Bushby, Anthony Dunn, Hugh Kilpatrick, Matthew R. Dreher, Z. A. Bascal, Marcus Caine, Xunli Zhang, Sean L. Willis, David Grey, Andrew L. Lewis, Andrew J. Bushby, Martyn Hill
Publikováno v:
Journal of the mechanical behavior of biomedical materials. 78
The purpose of this study was to evaluate LC Bead LUMI™ (40–90 µm and 70–150 µm) in order to determine if their increased resistance to compression influences microsphere penetration and distribution compared to more compressible commercial m
Publikováno v:
Advanced healthcare materials. 6(9)
Therapeutic embolotherapy is the deliberate occlusion of a blood vessel within the body, which can be for the prevention of internal bleeding, stemming of flow through an arteriovenous malformation, or occlusion of blood vessels feeding a tumour. Thi
Autor:
Andrew L. Lewis, Suman Chakraborty, Bibhas Roy, Martyn Hill, Xunli Zhang, Marcus Caine, Michele Carboni, Dario Carugo, Lorenzo Capretto
Anticancer treatment using embolic drug-eluting beads (DEBs) has shown multifarious advantages compared to systemic chemotherapy. However, there is a growing need for a better understanding of the physical parameters governing drug-elution from embol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685fc89bbc55ba8c18555a84adca5ec2
https://eprints.soton.ac.uk/389477/
https://eprints.soton.ac.uk/389477/
Autor:
Karun Sharma, Andrew L. Lewis, Matthew R. Dreher, Bradford J. Wood, Anthony Dunn, David Grey, Marcus Caine, Yiqing Tang, Vincent O’Byrne, Kirk D. Fowers, Brenda Hall, Carmen Gacchina Johnson
Publikováno v:
Journal of Materials Science. Materials in Medicine
Clinical use of DC Bead™ loaded with doxorubicin (DEBDOX™) or irinotecan (DEBIRI™), for the treatment of primary and secondary tumours of the liver respectively, is showing great promise. Recently there has been a tendency to select smaller bea
Autor:
Martyn Hill, Pedro Garcia, Matthew R. Dreher, Michael S. McCafferty, Xunli Zhang, Wayne M. Mullett, Marcus Caine, Andrew L. Lewis, Scott McGhee
Publikováno v:
Journal of Vascular and Interventional Radiology. (2):260-268.e2
Purpose: To investigate material density, flow, and viscosity effects on microsphere distribution within an in vitro model designed to simulate hepatic arteries.Materials and Methods: A vascular flow model was used to compare distribution of glass an