Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marcus C. Parrish"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 6 (2022)
Abstract Introduction: This research examined the perspective of the Huntington’s disease (HD) community regarding the use of predictive biomarkers as endpoints for regulatory approval of therapeutics to prevent or delay the onset of clinical HD i
Externí odkaz:
https://doaj.org/article/dccf8670eebc4c48b2695b9b5df5f695
Publikováno v:
Annual Review of Pharmacology and Toxicology. 59:405-421
With pharmaceutical companies shrinking their research departments and exiting out of efforts related to unprofitable diseases, society has become increasingly dependent on academic institutions to perform drug discovery and early-stage translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cd499a6beba20d13dee62b2aace681
https://doi.org/10.1146/annurev-pharmtox-010818-021625
https://doi.org/10.1146/annurev-pharmtox-010818-021625
Publikováno v:
Environmental and Molecular Mutagenesis. 58:508-521
DNA damage and alterations in global DNA methylation status are associated with multiple human diseases and are frequently correlated with clinically relevant information. Therefore, assessing DNA damage and epigenetic modifications, including DNA me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aed8a6c35550d9dbd85ee9c3c639dd8
https://doi.org/10.1002/em.22101
https://doi.org/10.1002/em.22101
Autor:
Orsolya Kiraly, Na Li, Marcus C. Parrish, Tze Khee Chan, Nona Abolhassani, Yamada Yoshiyuki, Kong-Bing Tan, Vincent T. K. Chow, Prashant Rai, Bevin P. Engelward, Lu Yin
Publikováno v:
Springer Basel
Influenza viruses account for significant morbidity worldwide. Inflammatory responses, including excessive generation of reactive oxygen and nitrogen species (RONS), mediate lung injury in severe influenza infections. However, the molecular basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f337348d0518be202e09d3ca7a02415f
https://doi.org/10.1007/s00018-015-1879-1
https://doi.org/10.1007/s00018-015-1879-1
Autor:
Bevin P. Engelward, Peter T. C. So, Paul Matsudaira, Marcus C. Parrish, Heejin Choi, Dushan N. Wadduwage
Publikováno v:
SPIE Proceedings.
Ionising radiation causes various types of DNA damages including double strand breaks (DSBs). DSBs are often recognized by DNA repair protein ATM which forms gamma-H2AX foci at the site of the DSBs that can be visualized using immunohistochemistry. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::416a9f79251430299bc42a746d576d96
https://doi.org/10.1117/12.2185005
https://doi.org/10.1117/12.2185005
Autor:
Prashant Rai, Marcus C. Parrish, Ian Jun Jie Tay, Jimmy Kwang, Fang He, Na Li, Bevin P. Engelward, Vincent T. K. Chow, Shelley Erin Ackerman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(26)
Streptococcus pneumoniae is a leading cause of pneumonia and one of the most common causes of death globally. The impact of S. pneumoniae on host molecular processes that lead to detrimental pulmonary consequences is not fully understood. Here, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0508cc3c39279471bc16418e7a2dff4a
https://pubmed.ncbi.nlm.nih.gov/26080406
https://pubmed.ncbi.nlm.nih.gov/26080406
Autor:
Michael Schleicher, Marcus C. Parrish, Themis R. Kyriakides, Tara A. Asoulin, Marie M. Krady, Susan MacLauchlan, William C. Sessa, Paul L. Huang, Jun Yu, Jianmin Zeng
Injury- and ischemia-induced angiogenesis is critical for tissue repair and requires nitric oxide (NO) derived from endothelial nitric oxide synthase (eNOS). We present evidence that NO induces angiogenesis by modulating the level of the angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2838d318da5b20e2cf2f78646c1c94a8
https://europepmc.org/articles/PMC3219156/
https://europepmc.org/articles/PMC3219156/
