Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marcus C. Moore"'
Autor:
Hossein Yarandi, Amanda M. Shaw, Jerry Ryan Holder, James B. Chambers, Deborah J. Clegg, William J. Millard, Zhimin Xiang, Marcus C. Moore, Carrie Haskell-Luevano, Rayna M. Bauzo, Boman G. Irani, Stephen C. Benoit, Bettina Proneth
Publikováno v:
European Journal of Pharmacology. 660:80-87
The melanocortin system is well recognized to be involved in the regulation of food intake, body weight, and energy homeostasis. To probe the role of the MC 3 in the regulation of food intake, JRH322-18 a mixed MC 3 partial agonist/antagonist and MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2570a7fb3e190f5f9fda38807c638d1
https://doi.org/10.1016/j.ejphar.2010.10.101
https://doi.org/10.1016/j.ejphar.2010.10.101
Autor:
Amy Andreasen, Glenn A. Walter, Kim R. Haskell, Lorraine M. Koerper, William J. Millard, Sally A. Litherland, Henry V. Baker, Francois Rouzaud, Marcus C. Moore, Carrie Haskell-Luevano, Jay W. Schaub, Zhimin Xiang
Publikováno v:
The FASEB Journal. 23:642-655
Exercise is a mechanism for maintenance of body weight in humans. Morbidly obese human patients have been shown to possess single nucleotide polymorphisms in the melanocortin-4 receptor (MC4R). MC4R knockout mice have been well characterized as a gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850c80b6f513e8768465fb9b2f48112
https://doi.org/10.1096/fj.08-109686
https://doi.org/10.1096/fj.08-109686
Publikováno v:
Peptides. 27:2829-2835
Melanocortin-4 receptor knockout (MC4RKO) mice are hyperphagic and develop obesity under free feeding conditions. We reported previously that MC4RKO mice did not maintain hyperphagia and as a result lost weight when required to press a lever to obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce9f74fb9493da41bc5b91807f09b99
https://doi.org/10.1016/j.peptides.2006.07.008
https://doi.org/10.1016/j.peptides.2006.07.008
Publikováno v:
Biochemical and Biophysical Research Communications. 326:638-644
The melanocortin system is involved in hypothalamic regulation of energy homeostasis. The melanocortin-4 receptor (MC4R) has been linked to both obesity and reproductive dysfunction. Deletion of the MC4R from the mouse genome has resulted in phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8acf52214cb6899872e414dea541fd4
https://doi.org/10.1016/j.bbrc.2004.11.084
https://doi.org/10.1016/j.bbrc.2004.11.084
Publikováno v:
Peptides. 26(10)
We tested whether MC4R null mice display altered gustatory function relative to wild-type controls that may contribute to the characteristic hyperphagia and obesity associated with this gene deletion. Mice were tested for their licking responses to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9125082a105e994065a4b276296d996e
https://pubmed.ncbi.nlm.nih.gov/15993983
https://pubmed.ncbi.nlm.nih.gov/15993983
Publikováno v:
Peptides. 26(10)
Ghrelin stimulates food intake in part by activating hypothalamic neuropeptide Y (NPY) neurons/agouti related peptide (AGRP) neurons. We investigated the role of AGRP/melanocortin signaling in ghrelin-induced food intake by studying melanocortin 3 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbef434223f30f7a1ed38e52a7d2a58c
https://pubmed.ncbi.nlm.nih.gov/16005545
https://pubmed.ncbi.nlm.nih.gov/16005545
Publikováno v:
Physiologybehavior. 84(1)
We report the meal patterns of mice with the deletion of either the melanocortin type 3 or 4 receptors (MC3RKO or MC4RKO) compared with that of the wild type (WT) under conditions of varying foraging costs. Mice lived in two-lever operant chambers; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18c463c7b97c8c0ef15279eee2e7c26
https://pubmed.ncbi.nlm.nih.gov/15642615
https://pubmed.ncbi.nlm.nih.gov/15642615