Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Marcus A. Lawson"'
Autor:
Stephanie M. Matt, Jalisa D. Zimmerman, Marcus A. Lawson, Angela C. Bustamante, Monica Uddin, Rodney W. Johnson
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Activity of DNA methyltransferases (DNMTs), the enzymes that catalyze DNA methylation, is dynamically regulated in the brain. DNMT inhibitors alter DNA methylation globally in the brain and at individual neural plasticity-associated genes, but how DN
Externí odkaz:
https://doaj.org/article/9534134a08af42e49b218607d5e5814e
Autor:
Stephanie M. Matt, Jacob M. Allen, Marcus A. Lawson, Lucy J. Mailing, Jeffrey A. Woods, Rodney W. Johnson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Aging results in chronic systemic inflammation that can alter neuroinflammation of the brain. Specifically, microglia shift to a pro-inflammatory phenotype predisposing them to hyperactivation upon stimulation by peripheral immune signals. It is prop
Externí odkaz:
https://doaj.org/article/4ee0809fabf34ea4a394b0d2a219fd35
Autor:
Stephanie M. Matt, Aditi Das, Adrienne M. Antonson, Megan P. Caputo, Rodney W. Johnson, Josephine E. Watson, Marcus A. Lawson, Brian J. Leyshon, Emily C. Radlowski
Publikováno v:
Brain Behav Immun
Neonatal brain development can be disrupted by infection that results in microglial cell activation and neuroinflammation. Studies indicate that polyunsaturated fatty acids (PUFAs) and their metabolites can resolve inflammation. It is not known if di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1adf1c23db98cbeb5e875849975ca9
https://doi.org/10.1016/j.bbi.2019.06.046
https://doi.org/10.1016/j.bbi.2019.06.046
Autor:
Marcus A. Lawson, Adrienne M. Antonson, Megan P. Caputo, Stephanie M. Matt, Brian J. Leyshon, Rodney W. Johnson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:20190-20200
Maternal infections during pregnancy are associated with increased risk of neurodevelopmental disorders, although the precise mechanisms remain to be elucidated. Previously, we established a maternal immune activation (MIA) model using swine, which r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd704b87aa690e1d4394c788d800634
https://doi.org/10.1073/pnas.1817014116
https://doi.org/10.1073/pnas.1817014116
Autor:
Keith W. Kelley, Cong Wu, Sandra L. Rodriguez-Zas, Scott E. Nixon, Elena V. Romanova, Jason C. O'Connor, Bruce R. Southey, Marcus A. Lawson, Cynthia Zavala, Robert Dantzer, Jonathan V. Sweedler, Robert H. McCusker, Robmay Garcia
Publikováno v:
Psychoneuroendocrinology. 97:47-58
Background Peripheral immune challenge can elicit microglia activation and depression-related symptoms. The balance of inflammatory signals in the tryptophan pathway can skew the activity of indoleamine-pyrrole 2,3 dioxygenase (IDO1) towards the meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3f919f2a356460b237a28869d27252
https://doi.org/10.1016/j.psyneuen.2018.06.024
https://doi.org/10.1016/j.psyneuen.2018.06.024
Publikováno v:
Brain, Behavior, and Immunity. 69:321-335
Behavioral symptoms associated with mood disorders have been intimately linked with immunological and psychological stress. Induction of immune and stress pathways is accompanied by increased tryptophan entry into the Kynurenine (Kyn) Pathway as gove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbba97027614ad980fbefba47c74f8b
https://doi.org/10.1016/j.bbi.2017.12.006
https://doi.org/10.1016/j.bbi.2017.12.006
Autor:
Jennifer L. Rytych, Adrienne M. Antonson, Marcus A. Lawson, Emily C. Radlowski, Rodney W. Johnson
Publikováno v:
Brain, Behavior, and Immunity. 59:300-312
Maternal infection during pregnancy increases risk for neurodevelopmental disorders and reduced stress resilience in offspring, but the mechanisms are not fully understood. We hypothesized that piglets born from gilts infected with a respiratory viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36163e933ceb5f3c0013efb1c3df9f7
https://doi.org/10.1016/j.bbi.2016.09.019
https://doi.org/10.1016/j.bbi.2016.09.019
Autor:
Keith W. Kelley, Robert Dantzer, Scott E. Nixon, Sandra L. Rodriguez-Zas, Bruce R. Southey, Marcus A. Lawson, Robert H. McCusker, Jason C. O'Connor
Publikováno v:
Brain, Behavior, and Immunity. 44:176-186
Behavioral indicators in the murine Bacille Calmette Guerin (BCG) model of inflammation have been studied individually; however, the variability of the behaviors across BCG levels and the mouse-to-mouse variation within BCG-treatment group are only p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98206af46c7dba103c43fd83880cff1
Autor:
Marcus A. Lawson, Alexandra K. Brooks, Jennifer L. Rytych, Robin A. Smith, Cecilia Ocampo-Solis, Tiffany M. Janda, Robert H. McCusker
Publikováno v:
Brain, behavior, and immunity. 62
Abundant evidence connects depression symptomology with immune system activation, stress and subsequently elevated levels of kynurenine. Anti-depressants, such as the tricyclic norepinephrine/serotonin reuptake inhibitor desipramine (Desip), were dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8df2ee0325264058fc952aef6fa26a
https://pubmed.ncbi.nlm.nih.gov/28212884
https://pubmed.ncbi.nlm.nih.gov/28212884
Autor:
Robert H. McCusker, Alexandra K. Brooks, Gregory G. Freund, Andrew J. Steelman, Marcus A. Lawson
Publikováno v:
Brain, Behavior, and Immunity. 81:44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beb46aee7b174818c4b6cb0941374ca1
https://doi.org/10.1016/j.bbi.2019.08.146
https://doi.org/10.1016/j.bbi.2019.08.146