Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Marcus, Ståhlman"'
Autor:
Claudia D. Fuchs, Emmanuel D. Dixon, Tim Hendrikx, Veronika Mlitz, Annika Wahlström, Marcus Ståhlman, Hubert Scharnagl, Tatjana Stojakovic, Christoph J. Binder, Hanns‐Ulrich Marschall, Michael Trauner
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2368-2378 (2022)
Abstract Bile salt export pump (Bsep) (Abcb11)−/− mice are protected from acquired cholestatic injury due to metabolic preconditioning with a hydrophilic bile acid (BA) pool with formation of tetrahydroxylated bile acids (THBAs). We aimed to expl
Externí odkaz:
https://doaj.org/article/2eb49cbe92514bb2bf2ca7d245d3ffe7
Cholesterol efflux promoting function of high-density lipoproteins in calcific aortic valve stenosis
Autor:
Duygu Kocyigit, Francesca Zimetti, Kadri M. Gurses, Ilaria Zanotti, Cinzia Marchi, Marcus Ståhlman, Jan Borén, Hande Canpinar, Mehmet F.T. Soyal, Dicle Guc, Tuncay Hazirolan, Necla Ozer, Lale Tokgozoglu
Publikováno v:
Atherosclerosis Plus, Vol 44, Iss , Pp 18-24 (2021)
Background and aims: Cholesterol efflux capacity is a functional property of high-density lipoproteins (HDL) reflecting the efficiency of the atheroprotective reverse cholesterol transport process in humans. Its relationship with calcific aortic valv
Externí odkaz:
https://doaj.org/article/894bef3bc2e144078124fba7ff9125ec
Autor:
Mara Caputo, Emmelie Cansby, Sima Kumari, Yeshwant Kurhe, Syam Nair, Marcus Ståhlman, Nagaraj M. Kulkarni, Jan Borén, Hanns‐Ulrich Marschall, Matthias Blüher, Margit Mahlapuu
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1183-1200 (2021)
Nonalcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, primarily because of the massive global increase in obesity. Despite intense research efforts in this field, the factors that govern the initi
Externí odkaz:
https://doaj.org/article/4e024d45939a4d848075e192c67e1a5a
Autor:
Béatrice S.-Y. Choi, Noëmie Daniel, Vanessa P. Houde, Adia Ouellette, Bruno Marcotte, Thibault V. Varin, Cécile Vors, Perrine Feutry, Olga Ilkayeva, Marcus Ståhlman, Philippe St-Pierre, Fredrik Bäckhed, Angelo Tremblay, Phillip J. White, André Marette
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Diet-induced changes in the microbiome have been associated with obesity. Here, using a mouse model, the authors show that a mixed protein source found in western diets exacerbates diet-induced obesity and insulin resistance by potentiating hepatic m
Externí odkaz:
https://doaj.org/article/fd7e575509cd4ed1a49d204ec6f5f9de
Autor:
Cheng Zhang, Elias Bjornson, Muhammad Arif, Abdellah Tebani, Alen Lovric, Rui Benfeitas, Mehmet Ozcan, Kajetan Juszczak, Woonghee Kim, Jung Tae Kim, Gholamreza Bidkhori, Marcus Ståhlman, Per‐Olof Bergh, Martin Adiels, Hasan Turkez, Marja‐Riitta Taskinen, Jim Bosley, Hanns‐Ulrich Marschall, Jens Nielsen, Mathias Uhlén, Jan Borén, Adil Mardinoglu
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 4, Pp 1-16 (2020)
Abstract The prevalence of non‐alcoholic fatty liver disease (NAFLD) continues to increase dramatically, and there is no approved medication for its treatment. Recently, we predicted the underlying molecular mechanisms involved in the progression o
Externí odkaz:
https://doaj.org/article/78bdf233f671443a8fd70c046a3130ec
Autor:
Kay H. M. Roumans, Lucas Lindeboom, Pandichelvam Veeraiah, Carlijn M. E. Remie, Esther Phielix, Bas Havekes, Yvonne M. H. Bruls, Martijn C. G. J. Brouwers, Marcus Ståhlman, Marjan Alssema, Harry P. F. Peters, Renée de Mutsert, Bart Staels, Marja-Riitta Taskinen, Jan Borén, Patrick Schrauwen, Vera B. Schrauwen-Hinderling
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Here, the authors use 1H-MRS methodology to show hepatic SFA fraction is a measure o
Externí odkaz:
https://doaj.org/article/2c9a2f8b1cf44a76b5b73a890bc8f73e
Autor:
Annika Nerstedt, Yeshwant Kurhe, Emmelie Cansby, Mara Caputo, Lei Gao, Egor Vorontsov, Marcus Ståhlman, Esther Nuñez-Durán, Jan Borén, Hanns-Ulrich Marschall, Douglas G. Mashek, Darren N. Saunders, Carina Sihlbom, Andrew J. Hoy, Margit Mahlapuu
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 178-191 (2020)
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are emerging as leading causes of liver disease worldwide and have been recognized as one of the major unmet medical needs of the 21st century. Our recent translational
Externí odkaz:
https://doaj.org/article/5223ec8bf7604ecfadc7de925c7c5dab
Autor:
Susanne Keipert, Dominik Lutter, Bjoern O. Schroeder, Daniel Brandt, Marcus Ståhlman, Thomas Schwarzmayr, Elisabeth Graf, Helmut Fuchs, Martin Hrabe de Angelis, Matthias H. Tschöp, Jan Rozman, Martin Jastroch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Brown adipose thermogenesis increases energy expenditure and relies on uncoupling protein 1 (UCP1), however, UCP1 knock-out mice show resistance to diet-induced obesity at room temperature. Here, the authors show that this resistance relies on FGF21-
Externí odkaz:
https://doaj.org/article/9f6878bc1fa4458ca06f077b004448cb
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 995-1004 (2019)
The FA composition of phospholipids must be tightly regulated to maintain optimal cell membrane properties and compensate for a highly variable supply of dietary FAs. Previous studies have shown that AdipoR2 and its homologue PAQR-2 are important reg
Externí odkaz:
https://doaj.org/article/db4da3b7658d4b8da6451a37e5f02683
Autor:
Antonio Molinaro, Robert Caesar, Laurent L'homme, Ara Koh, Marcus Ståhlman, Bart Staels, Fredrik Bäckhed
Publikováno v:
Molecular Metabolism, Vol 23, Iss , Pp 82-87 (2019)
Objectives: The nuclear receptor superfamily is a potential target for the development of new treatments for obesity and metabolic diseases. Increasing evidence has pointed towards the retinoic acid-related orphan receptor-alpha (RORα) as an importa
Externí odkaz:
https://doaj.org/article/5fba586f534c4a26a0920342b16cbb9f