The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein

Autor: Kowaljow, Valeria, Marcowycz, Aline, Ansseau, Eugénie, Conde, Cecilia B., Sauvage, Sébastien, Mattéotti, Christel, Arias, Cristina, Corona, E. Daniel, Nuñez, Nicolás G., Leo, Oberdan, Wattiez, Ruddy, Figlewicz, Denise, Laoudj-Chenivesse, Dalila, Belayew, Alexandra, Coppée, Frédérique, Rosa, Alberto L.

Publikováno v: In Neuromuscular Disorders 2007 17(8):611-623

Bis-8-hydroxyquinoline and bis-8-hydroxyquinaldine N-substituted amines: A single methyl group structural difference between the two heterocycles, which modulates the antiproliferative effects.

Autor: Madonna, Sébastien¹, Marcowycz, Aline², Lamoral-Theys, Delphine³, Van Goietsenoven, Gwendoline², Dessolin, Jean⁴, Pirker, Christine⁵, Spiegl-Kreinecker, Sabine⁶, Biraboneye, César-Alain¹, Berger, Walter⁵, Kiss, Robert², Kraus, Jean-Louis¹ kraus@univmed.fr

Publikováno v: Journal of Heterocyclic Chemistry. May2010, Vol. 47 Issue 3, p719-723. 5p. 3 Diagrams, 1 Chart.

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines

Autor: Magali Barthelemy-Requin, Sabine Depauw, Delphine Lamoral-Theys, Jacques Dubois, Sébastien Madonna, Gaëlle Lenglet, Thierry Cresteil, Marie-Hélène David-Cordonnier, Christophe Beclin, Jean-Louis Kraus, Valérie Monnier, Robert Kiss, Geneviève Aubert, Younes Laras, Aline Marcowycz, Vincent Moret

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2010, 45 (2), pp.623-638. 〈10.1016/j.ejmech.2009.11.006〉
European Journal of Medicinal Chemistry, 2010, 45 (2), pp.623-638. ⟨10.1016/j.ejmech.2009.11.006⟩
European Journal of Medicinal Chemistry, Elsevier, 2010, 45 (2), pp.623-638. ⟨10.1016/j.ejmech.2009.11.006⟩
European Journal of Medicinal Chemistry, Elsevier, 2010, 45 (2), pp.623-38. ⟨10.1016/j.ejmech.2009.11.006⟩

International audience; A series of twenty six 8-hydroxyquinoline substituted amines, structurally related to compounds 2 and 3, were synthesized to evaluate the effects of structural changes on antitumor activity and understand their mechanism of ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b58b3dd6308b3f3e7310ac0534516a3
https://hal.archives-ouvertes.fr/hal-00563139

Bis-8-hydroxyquinoline and bis-8-hydroxyquinaldine N-substituted amines: A single methyl group structural difference between the two heterocycles, which modulates the antiproliferative effects

Autor: Christine Pirker, César-Alain Biraboneye, Walter Berger, Delphine Lamoral-Theys, Sabine Spiegl-Kreinecker, Aline Marcowycz, Robert Kiss, Sébastien Madonna, Jean Dessolin, Jean-Louis Kraus, Gwendoline Van Goietsenoven

Publikováno v: Journal of Heterocyclic Chemistry.

(Chemical Equation Presented) The synthesis of a series of bis-8-hydroxyquinoline- and bis-8-hydroxyquinaldine-substituted N-benzyl or thiophenyl amines and their corresponding bis-8-hydroxyquinoline is reported. In vitro growth inhibitory effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d34fb0e8d353d5531c16dac145f79627
https://doi.org/10.1002/jhet.304

In vitro anticancer potential of tree extracts from the Walloon Region forest

Autor: Véronique Megalizzi, Ewa Cieckiewicz, Aline Marcowycz, Luc Angenot, Robert Kiss, Michel Frederich

Publikováno v: Planta medica. 75(15)

Forty-eight extracts from 16 common Belgian trees from the Walloon Region forest were evaluated for in vitro growth inhibitory activity against the human LoVo colon cancer, PC3 prostate cancer, and U373 glioblastoma cell lines. Our study was performe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263fac2d05a03e8278c5dfa03cfef2a5
https://pubmed.ncbi.nlm.nih.gov/19579185