Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marcos Steinberg"'
Autor:
Marcos Steinberg, Darina Spasova, Danelle Eto, AnneMarie Pferdekamper, Phuong Nguyen, Brian Le, Zachary Naiman, Susan Murphy, Maricel Gozo, James Skipper, Taylor Ismaili, Xikui Liu, Sunil Sahdeo, Xiao Hu, Isharat Yusuf, Kristen Taylor Meadows, Laura Carter
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Carole Soussain, Christian Grommes, Samar Issa, Renee Ward, Caryn Peterson, Matt Cravets, Anita Mathias, Judith Sosa, Brian Kirby, Zhaoqing Ding, Isharat Yusuf, Mark Rose, Marcos Steinberg, Han W Tun
Publikováno v:
Neuro-Oncology Advances. 4:i9-i9
BTK plays an important role in B cell receptor and Toll-like receptor signaling pathways, which are constitutively active in primary CNS lymphomas, and hence represents an excellent therapeutic target. Ibrutinib, a first-generation BTKi, was evaluate
Autor:
Hans Yssel, Louise Swainson, Wilhelm Friedrich, Naomi Taylor, M Boyer, Marcos Steinberg, Klaus Schwarz, Nelly Noraz
Publikováno v:
Gene Therapy
Gene Therapy, Nature Publishing Group, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, Nature Publishing Group, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Humans lacking the ZAP-70 protein tyrosine kinase present with an absence of CD8+ T cells and defective CD4+ T cells in the periphery. This severe combined immunodeficiency is fatal unless treated by allogeneic bone marrow transplantation. However, i
Autor:
Louise Swainson, Peggy Merida, Vincenzo Di Bartolo, Naomi Taylor, Nelly Noraz, Marcos Steinberg, Ludivine Pelletier, Oumeya Adjali
Publikováno v:
Blood
Blood, 2004, 104 (3), pp.760--7. ⟨10.1182/blood-2003-12-4314⟩
Blood, American Society of Hematology, 2004, 104 (3), pp.760--7. ⟨10.1182/blood-2003-12-4314⟩
Blood, 2004, 104 (3), pp.760--7. ⟨10.1182/blood-2003-12-4314⟩
Blood, American Society of Hematology, 2004, 104 (3), pp.760--7. ⟨10.1182/blood-2003-12-4314⟩
Engagement of the T-cell receptor (TCR) results in the activation of Lck/Fyn and ZAP-70/Syk tyrosine kinases. Lck-mediated tyrosine phosphorylation of signaling motifs (ITAMs) in the CD3-ζ subunits of the TCR is an initial step in the transduction o
Autor:
Kevin B. Bacon, Hans Yssel, Cosette Rebouissou, Valérie Dardalhon, Nelly Noraz, Marcos Steinberg, Naomi Taylor, Klaus Schwarz, Wilhelm Friedrich, Robert A. Hipskind
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2000, 275 (21), pp.15832--8. ⟨10.1074/jbc.M908568199⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2000, 275 (21), pp.15832--8. ⟨10.1074/jbc.M908568199⟩
International audience; ZAP-70-deficient patients present with nonfunctional CD4+ T cells in the periphery. We find that a subset of primary ZAP-70-deficient T cells, expressing high levels of the related protein-tyrosine kinase Syk, can proliferate