Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Marcos Seoane"'
Autor:
Pablo Iglesias, Marcos Seoane, Irene Golán-Cancela, Máximo Fraga, Victor M. Arce, Jose A. Costoya
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8849 (2023)
In recent years, new therapies have been developed based on molecules that target molecular mechanisms involved in both the initiation and maintenance of the oncogenic process. Among these molecules are the poly(ADP-ribose) polymerase 1 (PARP1) inhib
Externí odkaz:
https://doaj.org/article/0e79acad2b77416cb81f2433b484ceb6
Autor:
Costoya, Pablo Iglesias, Marcos Seoane, Irene Golán-Cancela, Máximo Fraga, Victor M. Arce, Jose A.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8849
In recent years, new therapies have been developed based on molecules that target molecular mechanisms involved in both the initiation and maintenance of the oncogenic process. Among these molecules are the poly(ADP-ribose) polymerase 1 (PARP1) inhib
Autor:
Pablo Iglesias, Marcos Seoane, Irene Golán-Cancela, Maximo Fraga, Víctor M. Arce, Jose A. Costoya
In recent years, new therapies have been developed based on molecules that target mo-lecular mechanisms involved in both the initiation and maintenance of the oncogenic process. Among these molecules are the poly (ADP-ribose) polymerase 1 (PARP1) inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0a416b32fcf6ca6a7a03be7fa84b37
https://doi.org/10.20944/preprints202304.0530.v1
https://doi.org/10.20944/preprints202304.0530.v1
Autor:
Ann-Christin Puller, Jürgen Müller, Sabine Raasch, Daniela Indenbirken, Lia Burkhardt, Marcos Seoane, Pablo A. Iglesias, Martin A. Horstmann, Marianne Klokow, Michael Spohn
Publikováno v:
Blood Adv
Aberrant expression of the transcriptional modulator and early B-cell factor 1 (EBF1) antagonist ZNF423 has been implicated in B-cell leukemogenesis, but its impact on transcriptional circuitries in lymphopoiesis has not been elucidated in a comprehe
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 1, Pp 111-120 (2013)
Background: Fas/CD95 is the best-studied member of the death receptor (DR) superfamily in the central nervous system where it can trigger cellular responses other than apoptosis, including the promotion of neurogenesis and neuritogenesis, stimulation
Externí odkaz:
https://doaj.org/article/ae579e30c50b47ba9ce42c6a84bc3d7b
Immortalization of a cell line with neural stem cell characteristics derived from mouse embryo brain
Autor:
Máximo Fraga, Víctor M. Arce, Marcos Seoane, Pilar Caamaño, Jose A. Costoya, Cristina Almengló, Tamara González-Mosquera, Jesús Devesa
Publikováno v:
Developmental Dynamics. 249:112-124
Background Neural stem cells (NSC) have been extensively used as a tool to investigate the mechanisms responsible for neural repair, and they have been also considered as the source for a series of promising replacement therapies in various neurodege
Autor:
Irene Golán-Cancela, Jose A. Costoya, Pablo Iglesias, Marcos Seoane, Máximo Fraga, Víctor M. Arce, Isabel Castro-Piedras
In recent years, poly (ADP-ribose) polymerase (PARP) inhibitors have heen evaluated for treating homologous recombination-deficient tumors, taking advantage of synthetic lethality. However, increasing evidence indicates that PARP proteins exert sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9880a854a69665b35f8686d9bbe3b4
Autor:
Marcos Seoane Chouciño
Publikováno v:
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
TDR: Tesis Doctorales en Red
CBUC, CESCA
TDR. Tesis Doctorales en Red
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
TDR: Tesis Doctorales en Red
CBUC, CESCA
Tesi en modalitat de cotutela: Universitat Politècnica de Catalunya i Swansea University Magnetic Resonance Imaging (MRI) scanners have become an essential tool in the medical industry due to their ability to produce high resolution images of the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49487fc2ba3bed9bdf74cdcca67d13ac
https://hdl.handle.net/2117/33340210803/670022
https://hdl.handle.net/2117/33340210803/670022
Autor:
Víctor M. Arce, Isabel Castro-Piedras, Pablo Iglesias, Irene Golán, Marcos Seoane, Máximo Fraga, Jose A. Costoya
Publikováno v:
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Cancers, Vol 12, Iss 2907, p 2907 (2020)
Cancers
Volume 12
Issue 10
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Universidad de Santiago de Compostela (USC)
Cancers, Vol 12, Iss 2907, p 2907 (2020)
Cancers
Volume 12
Issue 10
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Simple Summary PARP1 is one of the best characterized enzymes in DNA repair and an attractive target for drug design in cancer therapies. Beyond repair, PARP1 modulates the activity of several transcription factors, of which E2F1 stands out given its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6339ff94bdcf897ec22902788ab8cd1
http://hdl.handle.net/10347/23767
http://hdl.handle.net/10347/23767
A feasible implementation of a novel X-ray detector for highly energetic X-ray photons with a large solid angle coverage, optimal for the detection of Compton X-ray scattered photons, is described. The device consists of a 20 cm-thick sensitive volum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98713e1202fc2ef53c11ade4b609e40f