Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marcos S. Freire"'
Autor:
Gisela F. Trindade, Renato S. Marchevsky, Ana M.B. de Fillipis, Rita M.R. Nogueira, Myrna C. Bonaldo, Pedro C. Acero, Elena Caride, Marcos S. Freire, Ricardo Galler
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 80, Iss 2, Pp 311-321 (2008)
For the development of safe live attenuated flavivirus vaccines one of the main properties to be established is viral replication. We have used real-time reverse transcriptase-polymerase chain reaction and virus titration by plaque assay to determine
Externí odkaz:
https://doaj.org/article/5e782f563af44c76a40aaba5db3ccbbf
Autor:
Adriana S Azevedo, Anna M Y Yamamura, Marcos S Freire, Gisela F Trindade, Myrna Bonaldo, Ricardo Galler, Ada M B Alves
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e20528 (2011)
Two DNA vaccines were constructed encoding the ectodomain (domains I, II and III) of the DENV2 envelope protein (pE1D2) or only its domain III (pE2D2), fused to the human tissue plasminogen activator signal peptide (t-PA). The expression and secretio
Externí odkaz:
https://doaj.org/article/b93119332faf4a7aa16d1ebb630c57ff
Autor:
Mônica, da Silva-Nunes, Vanda A F, de Souza, Cláudio S, Pannuti, Márcia A, Sperança, Ana Carolina B, Terzian, Maurício L, Nogueira, Anna M Y, Yamamura, Marcos S, Freire, Natal S, da Silva, Rosely S, Malafronte, Pascoal T, Muniz, Helena B, Vasconcelos, Eliana V P, da Silva, Pedro F C, Vasconcelos, Marcelo U, Ferreira
Publikováno v:
The American journal of tropical medicine and hygiene. 79(4)
A comparison of dengue virus (DENV) antibody levels in paired serum samples collected from predominantly DENV-naive residents in an agricultural settlement in Brazilian Amazonia (baseline seroprevalence, 18.3%) showed a seroconversion rate of 3.67 ep
Autor:
Myrna C, Bonaldo, Richard C, Garratt, Philippe S, Caufour, Marcos S, Freire, Mauricio M, Rodrigues, Ruth S, Nussenzweig, Ricardo, Galler
Publikováno v:
Journal of molecular biology. 315(4)
The yellow fever 17D virus (YF17D) has several characteristics that are desirable for the development of new, live attenuated vaccines. We approached its development as a vector for heterologous antigens by studying the expression of a humoral epitop
Autor:
Vivian I Avelino-Silva, Karina T Miyaji, Peter W Hunt, Yong Huang, Marisol Simoes, Sheila B Lima, Marcos S Freire, Helio H Caiaffa-Filho, Marisa A Hong, Dayane Alves Costa, Juliana Zanatta C Dias, Natalia B Cerqueira, Anna Shoko Nishiya, Ester Cerdeira Sabino, Ana M Sartori, Esper G Kallas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005219 (2016)
BACKGROUND:HIV-infected individuals have deficient responses to Yellow Fever vaccine (YFV) and may be at higher risk for adverse events (AE). Chronic immune activation-characterized by low CD4/CD8 ratio or high indoleamine 2,3-dioxygenase-1 (IDO) act
Externí odkaz:
https://doaj.org/article/ca6497348fc24893b7bdb3467107efec
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 95, Pp 215-223 (2000)
The Flaviviridae is a family of about 70 mostly arthropod-borne viruses many of which are major public health problems with members being present in most continents. Among the most important are yellow fever (YF), dengue with its four serotypes and J
Externí odkaz:
https://doaj.org/article/50eeec648ee84820ba83aeb8c0375802
Autor:
Adriana S Azevedo, Antônio J S Gonçalves, Marcia Archer, Marcos S Freire, Ricardo Galler, Ada M B Alves
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58357 (2013)
The dengue envelope glycoprotein (E) is the major component of virion surface and its ectodomain is composed of domains I, II and III. This protein is the main target for the development of a dengue vaccine with induction of neutralizing antibodies.
Externí odkaz:
https://doaj.org/article/5f5876a497c649f9acf93b7668f240b1
Autor:
Simone M Costa, Anna Paula Yorio, Antônio J S Gonçalves, Mariana M Vidale, Emmerson C B Costa, Ronaldo Mohana-Borges, Marcia A Motta, Marcos S Freire, Ada M B Alves
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25685 (2011)
The dengue non-structural 3 (NS3) is a multifunctional protein, containing a serino-protease domain, located at the N-terminal portion, and helicase, NTPase and RTPase domains present in the C-terminal region. This protein is considered the main targ
Externí odkaz:
https://doaj.org/article/f4e9db6ee5074ed5a0e810a3960ca31a