Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marcos Morgan"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Coronaviruses are positive-strand RNA viruses with 3′ polyadenylated genomes and subgenomic transcripts. The lengths of the viral poly(A) tails change during infection by mechanisms that remain poorly understood. Here, we use a splint-liga
Externí odkaz:
https://doaj.org/article/0b54dfdcb17541359f0d71d58e25f4de
Autor:
Ru-pin Alicia Chi, Xiaojiang Xu, Jian-Liang Li, Xin Xu, Guang Hu, Paula Brown, Cynthia Willson, Oleksandr Kirsanov, Christopher Geyer, Chou-Long Huang, Marcos Morgan, Francesco DeMayo
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107616- (2023)
Summary: WNK1 is an important regulator in many physiological functions, yet its role in male reproduction is unexplored. In the male germline, WNK1 is upregulated in preleptotene spermatocytes indicating possible function(s) in spermatogenic meiosis
Externí odkaz:
https://doaj.org/article/d47ae584b41947e0acbc4325621d253b
Autor:
Marine Baptissart, Brian N. Papas, Ru-pin Alicia Chi, Yin Li, Dongwon Lee, Bhairavy Puviindran, Marcos Morgan
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107511- (2023)
Summary: Cell differentiation is associated with global changes in translational activity. Here, we characterize how mRNA poly(A) tail processing supports this dynamic. We observe that decreased translation during neuronal differentiation of P19 cell
Externí odkaz:
https://doaj.org/article/de37f9be23fa471293e18850610a1f60
Autor:
Azzurra Codino, Tomasz Turowski, Louie N. van de Lagemaat, Ivayla Ivanova, Andrea Tavosanis, Christian Much, Tania Auchynnikava, Lina Vasiliauskaitė, Marcos Morgan, Juri Rappsilber, Robin C. Allshire, Kamil R. Kranc, David Tollervey, Dónal O'Carroll
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102762- (2021)
Summary: Spermatogonial stem cells (SSCs) sustain spermatogenesis and fertility throughout adult male life. The conserved RNA-binding protein NANOS2 is essential for the maintenance of SSCs, but its targets and mechanisms of function are not fully un
Externí odkaz:
https://doaj.org/article/c901871256cd489d8e9d27e417a6e14f
Autor:
Elyse Kozlowski, Gregory A Wasserman, Marcos Morgan, Dónal O'Carroll, Nora-Guadalupe P Ramirez, Suryaram Gummuluru, Jasmine Y Rah, Adam C Gower, Michael Ieong, Lee J Quinton, Joseph P Mizgerd, Matthew R Jones
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179797 (2017)
Alveolar macrophages orchestrate pulmonary innate immunity and are essential for early immune surveillance and clearance of microorganisms in the airways. Inflammatory signaling must be sufficiently robust to promote host defense but limited enough t
Externí odkaz:
https://doaj.org/article/1b2675be230c4b7187e7e112a5852c34
Autor:
Stefano Comazzetto, Monica Di Giacomo, Kasper Dindler Rasmussen, Christian Much, Chiara Azzi, Emerald Perlas, Marcos Morgan, Dónal O'Carroll
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004597 (2014)
Male fertility requires the continuous production of high quality motile spermatozoa in abundance. Alterations in all three metrics cause oligoasthenoteratozoospermia, the leading cause of human sub/infertility. Post-mitotic spermatogenesis inclusive
Externí odkaz:
https://doaj.org/article/02729a72e6344132b5756a9e628216bf
Publikováno v:
Cell Mol Life Sci
Multiple RNA pathways are required to produce functional sperm. Here, we review RNA post-transcriptional regulation during spermatogenesis with particular emphasis on the role of 3' end modifications. From early studies in the 1970s, it became clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b48c6080752804788bc1b1dd2c75168
https://doi.org/10.1007/s00018-021-04012-4
https://doi.org/10.1007/s00018-021-04012-4
Autor:
Ru-pin Alicia Chi, Xiaojiang Xu, Jian-Liang Li, Xin Xu, Guang Hu, Paula Brown, Cynthia Willson, Oleksandr Kirsanov, Christopher B. Geyer, Chou-Long Huang, Marcos Morgan, Francesco John DeMayo
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f6a6185e86f2326dc1c0a62d54602ec
https://doi.org/10.2139/ssrn.4314975
https://doi.org/10.2139/ssrn.4314975
Autor:
Majid Mehravar, Yogesh Kumar, Moshe Olshansky, Pushkar Dakle, Michael Bullen, Varun K. Pandey, Dhiru Bansal, Craig Dent, Dhaval Hathiwala, Zhongming Zhang, Hetvi Gandhi, Alex Fulcher, Cheng Huang, Jonathan Price, Senthil Arumugam, Stephanie Ceman, Sureshkumar Balasubramanian, Brian N Papas, Marcos Morgan, Eric A Miska, Ralf B Schittenhelm, Pratibha Tripathi, Partha Pratim Das
N6-methyladenosine (m6A) is the most predominant internal mRNA modification in eukaryotes, recognised by its reader proteins (so-called m6A-readers) for regulating subsequent mRNA fates — splicing, export, localisation, decay, stability, and transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edd44f1681caa1ca7cd2816aacc7bfe6
https://doi.org/10.1101/2021.08.11.456030
https://doi.org/10.1101/2021.08.11.456030
Autor:
Andrea Tavosanis, Robin C. Allshire, Tania Auchynnikava, Louie N. van de Lagemaat, David Tollervey, Juri Rappsilber, Kamil R. Kranc, Azzurra Codino, Marcos Morgan, Lina Vasiliauskaitė, Ivayla Ivanova, Tomasz W. Turowski, Dónal O'Carroll, Christian Much
Publikováno v:
Codino, A, Turowski, T, Van De Lagemaat, L N, Ivanova, I, Tavosanis, A, Much, C, Auchynnikava, T, Vasiliauskaitė, L, Morgan, M, Rappsilber, J, Allshire, R C, Kranc, K R, Tollervey, D & O'carroll, D 2021, ' NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells ', iScience, vol. 24, no. 7, pp. 102762 . https://doi.org/10.1016/j.isci.2021.102762
iScience, Vol 24, Iss 7, Pp 102762-(2021)
iScience
iScience, Vol 24, Iss 7, Pp 102762-(2021)
iScience
Summary Spermatogonial stem cells (SSCs) sustain spermatogenesis and fertility throughout adult male life. The conserved RNA-binding protein NANOS2 is essential for the maintenance of SSCs, but its targets and mechanisms of function are not fully und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f0d604f36300b40fac0b9c874461a3
https://www.pure.ed.ac.uk/ws/files/222714014/PIIS2589004221007306.pdf
https://www.pure.ed.ac.uk/ws/files/222714014/PIIS2589004221007306.pdf