Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Marcos M. Pires"'
Autor:
Amaris J. Cardenas, Keena S. Thomas, Mary W. Broden, Noel J. Ferraro, Marcos M. Pires, Constance M. John, Gary A. Jarvis, Alison K. Criss
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTGonorrhea, caused by the bacterium Neisseria gonorrhoeae (Gc), is characterized by neutrophilic influx to infection sites. Gc has developed mechanisms to resist killing by neutrophils that include modifications to its surface lipooligosacchar
Externí odkaz:
https://doaj.org/article/7f6122ee6b0e4c4a85bfb334024f3999
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic T lymphocytes are the primary effector immune cells responsible for protection against cancer, as they target peptide neoantigens presented through the major histocompatibility complex (MHC) on cancer cells, leading to cell death. Targeting
Externí odkaz:
https://doaj.org/article/8ab739d49e3c4917b2b7770f99163453
Autor:
Moagi T. Shaku, Karl L. Ocius, Alexis J. Apostolos, Marcos M. Pires, Michael S. VanNieuwenhze, Neeraj Dhar, Bavesh D. Kana
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionMycobacteria assemble a complex cell wall with cross-linked peptidoglycan (PG) which plays an essential role in maintenance of cell wall integrity and tolerance to osmotic pressure. We previously demonstrated that various hydrolytic enzym
Externí odkaz:
https://doaj.org/article/4ff92e4651f84d5a8ce6b5e15a5b4d08
Autor:
George M. Ongwae, Mahendra D. Chordia, Jennie L. Cawley, Brianna E. Dalesandro, Nathan J. Wittenberg, Marcos M. Pires
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Bacteriophages are highly abundant molecular machines that have evolved proteins to target the surface of host bacterial cells. Given the ubiquity of lipopolysaccharides (LPS) on the outer membrane of Gram-negative bacteria, we reasoned that
Externí odkaz:
https://doaj.org/article/29f823eae76b4855ba53264c7f0d001d
Autor:
Brianna E. Dalesandro, Marcos M. Pires
Publikováno v:
Journal of Medicinal Chemistry. 66:503-515
Autor:
George M. Ongwae, Irene Lepori, Mahendra D. Chordia, Brianna E. Dalesandro, Alexis J. Apostolos, M. Sloan Siegrist, Marcos M. Pires
Publikováno v:
ACS Infectious Diseases. 9:97-110
Some of the most dangerous bacterial pathogens (Gram-negative and mycobacterial) deploy a formidable secondary membrane barrier to reduce the influx of exogenous molecules. For Gram-negative bacteria, this second exterior membrane is known as the out
Autor:
Moagi T. Shaku, Peter Um, Karl L. Ocius, Alexis J. Apostolos, Marcos M. Pires, William R. Bishai, Bavesh D. Kana
Publikováno v:
bioRxiv
Mechanisms by whichMycobacterium tuberculosis(Mtb) evades pathogen recognition receptor activation during infection may offer insights for the development of improved tuberculosis (TB) vaccines. Whilst Mtb elicits NOD-2 activation through host recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6c1fc4ed762ff7acf3a61c225d78fc
https://europepmc.org/articles/PMC10187164/
https://europepmc.org/articles/PMC10187164/
Autor:
Noel J. Ferraro, Marcos M. Pires
Publikováno v:
Bioconjugate Chemistry. 33:767-772
Autor:
Zichen Liu, Irene Lepori, Mahendra D. Chordia, Brianna E. Dalesandro, Taijie Guo, Jiajia Dong, M. Sloan Siegrist, Marcos M. Pires
Publikováno v:
Angewandte Chemie. 135
Autor:
Brianna E. Dalesandro, Joey J. Kelly, Zichen Liu, Mahendra D. Chordia, George M. Ongwae, Marcos M. Pires
Publikováno v:
bioRxiv
Staphylococcus aureus(S. aureus) has evolved the ability to persist after uptake into host immune cells. This intracellular niche enablesS. aureusto potentially escape host immune responses and survive the action of antibiotics. The elevated toleranc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fdc6f3d6a01b842eefaa32e7df1fff
https://europepmc.org/articles/PMC9949086/
https://europepmc.org/articles/PMC9949086/