Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marcos Lovelle"'
Publikováno v:
Methods. 127:30-36
Lipid droplets (LDs) are regulated neutral lipid storage organelles having a central role in numerous cellular processes as well as in various pathologies such as metabolic disorders, immune responses and during pathogen infection. Due to the growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e635c3a4fc47a5bc61ab332d304574
https://doi.org/10.1016/j.ymeth.2017.05.010
https://doi.org/10.1016/j.ymeth.2017.05.010
Autor:
Mathias Winterhalter, Kozhinjampara R. Mahendran, Matteo Ceccarelli, Pratik Raj Singh, Marcos Lovelle
Publikováno v:
The journal of physical chemistry. B 116 (2012): 4433–4438. doi:10.1021/jp2123136
info:cnr-pdr/source/autori:Singh PR; Ceccarelli M; Lovelle M; Winterhalter M; Mahendran KR/titolo:Antibiotic Permeation across the OmpF Channel: Modulation of the Affinity Site in the Presence of Magnesium/doi:10.1021%2Fjp2123136/rivista:The journal of physical chemistry. B/anno:2012/pagina_da:4433/pagina_a:4438/intervallo_pagine:4433–4438/volume:116
info:cnr-pdr/source/autori:Singh PR; Ceccarelli M; Lovelle M; Winterhalter M; Mahendran KR/titolo:Antibiotic Permeation across the OmpF Channel: Modulation of the Affinity Site in the Presence of Magnesium/doi:10.1021%2Fjp2123136/rivista:The journal of physical chemistry. B/anno:2012/pagina_da:4433/pagina_a:4438/intervallo_pagine:4433–4438/volume:116
We characterize the rate-limiting interaction of the antibiotic enrofloxacin with OmpF, a channel from the outer cell wall of Escherichia coli . Reconstitution of a single OmpF trimer into planar lipid membranes allows measurement of the ion current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c325eef22b42384fd2e50b6dc4bcc00
https://doi.org/10.1021/jp2123136
https://doi.org/10.1021/jp2123136
Autor:
Tivadar Mach, Paula Gameiro, Kozhinjampara R. Mahendran, Helge Weingart, Mathias Winterhalter, Marcos Lovelle
Publikováno v:
Physical chemistry chemical physics : PCCP. 13(4)
Outer membrane channels in Gram-negative bacteria are implicated in the influx of the latest generation of cephalosporins. We have measured the interaction strengths of ceftriaxone, cefpirome and ceftazidime in the two most abundant outer membrane po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e956d705f9570642f7baaf3e2e5366
https://pubmed.ncbi.nlm.nih.gov/21152583
https://pubmed.ncbi.nlm.nih.gov/21152583
Autor:
Kozhinjampara R. Mahendran, Helge Weingart, Mathias Winterhalter, Matteo Ceccarelli, Eric Hajjar, Marcos Lovelle, Tivadar Mach, Amit Kumar, Enrico Spiga, Paula Gameiro, Isabel Sousa
Publikováno v:
114 (2010): 5170–5179.
info:cnr-pdr/source/autori:Mahendran, Kozhinjampara R.; Hajjar, Eric; Mach, Tivadar; Lovelle, Marcos; Kumar, Amit; Sousa, Isabel; Spiga, Enrico; Weingart, Helge; Gameiro, Paula; Winterhalter, Mathias; Ceccarelli, Matteo/titolo:Molecular Basis of Enrofloxacin Translocation through OmpF, an Outer Membrane Channel of Escherichia coli-When Binding Does Not Imply Translocation/doi:/rivista:/anno:2010/pagina_da:5170/pagina_a:5179/intervallo_pagine:5170–5179/volume:114
info:cnr-pdr/source/autori:Mahendran, Kozhinjampara R.; Hajjar, Eric; Mach, Tivadar; Lovelle, Marcos; Kumar, Amit; Sousa, Isabel; Spiga, Enrico; Weingart, Helge; Gameiro, Paula; Winterhalter, Mathias; Ceccarelli, Matteo/titolo:Molecular Basis of Enrofloxacin Translocation through OmpF, an Outer Membrane Channel of Escherichia coli-When Binding Does Not Imply Translocation/doi:/rivista:/anno:2010/pagina_da:5170/pagina_a:5179/intervallo_pagine:5170–5179/volume:114
The molecular pathway of enrofloxacin, a fluoroquinolone antibiotic, through the outer membrane channel OmpF of Escherichia coli is investigated. High-resolution ion current fluctuation analysis reveals a strong affinity for enrofloxacin to OmpF, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4240f06b5005d98eb7b72d1c15c3702f
https://pubmed.ncbi.nlm.nih.gov/20349984
https://pubmed.ncbi.nlm.nih.gov/20349984
Autor:
Marcos Lovelle, Mathias Winterhalter, Tivadar Mach, Paula Gameiro, Kozhinjampara R. Mahendran
Publikováno v:
Biophysical Journal. 98(3)
Antibiotic resistance is emerging in Gram-negative bacteria worldwide. The outer membrane of Gram-negative bacteria is a formidable selective barrier, and a major factor in broad-spectrum antibiotic resistance. Influx of antibiotics into the Periplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a33438eaa011b71c8e831b83531657
Autor:
Mathias Winterhalter, Isabel Sousa, Paula Gameiro, Marcos Lovelle, Eric Hajjar, Amit Kumar, Tivadar Mach, Kozhinjampara R. Mahendran, Matteo Ceccarelli
Publikováno v:
Biophysical Journal. 98:375a
The molecular pathway of enrofloxacin, a fluoroquinolone antibiotic, across the main outer membrane channel OmpF of E. coli is investigated. Through high-resolution ion current fluctuation analysis we count single enrofloxacin channel penetrations, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2c51abd8e190c22eba4fb2c75981d6
https://doi.org/10.1016/j.bpj.2009.12.2022
https://doi.org/10.1016/j.bpj.2009.12.2022
Publikováno v:
Biophysical Journal. (3):151a-152a
The cephalosporins are bactericidal with both gram-positive and gram-negative activity widely prescribed because of their broad spectrum. Even though most of these antibiotics appear to penetrate the outer membrane through porin proteins, we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0252f6c917bb9357a266f5878ef47baa
Publikováno v:
Biophysical Journal. (3):151a
The outer membrane of Gram-negative bacteria is a protective diffusion barrier preventing the free entry of solutes into the periplasm. At the same time, the embedded proteins (Omp's for Outer Membrane Proteins) fulfil a number of tasks that are cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6082025875cf3d6d635c1b0c634419ad