Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Marcos J. Arauzo-Bravo"'
Autor:
Cinzia Cocola, Edoardo Abeni, Valentina Martino, Eleonora Piscitelli, Paride Pelucchi, Ettore Mosca, Alice Chiodi, Tasnim Mohamed, Mira Palizban, Giovanni Porta, Helga Palizban, Giovanni Nano, Francesco Acquati, Antonino Bruno, Burkhard Greve, Daniela Gerovska, Valerio Magnaghi, Daniela Mazzaccaro, Giovanni Bertalot, James Kehler, Cristiana Balbino, Marcos J. Arauzo-Bravo, Martin Götte, Ileana Zucchi, Rolland A. Reinbold
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3967 (2024)
High-grade gliomas (HGGs) and glioblastoma multiforme (GBM) are characterized by a heterogeneous and aggressive population of tissue-infiltrating cells that promote both destructive tissue remodeling and aberrant vascularization of the brain. The for
Externí odkaz:
https://doaj.org/article/dfe3f3cb50aa475ca17ea2aed7889a1b
Autor:
Wardah Mahmood, Lars Erichsen, Pauline Ott, Wolfgang A. Schulz, Johannes C. Fischer, Marcos J. Arauzo-Bravo, Marcelo L. Bendhack, Mohamed Hassan, Simeon Santourlidis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract LINE-1 hypomethylation of cell-free DNA has been described as an epigenetic biomarker of human aging. However, in the past, insufficient differentiation between cellular and cell-free DNA may have confounded analyses of genome-wide methylati
Externí odkaz:
https://doaj.org/article/9945070da77641ddb99a7d48f519ce43
Autor:
Wardah Mahmood, Lars Erichsen, Pauline Ott, Wolfgang A. Schulz, Johannes C. Fischer, Marcos J. Arauzo‑Bravo, Marcelo L. Bendhack, Mohamed Hassan, Simeon Santourlidis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/a7e237b7618a4ea1a8367934ad053fa6
Autor:
Isabel Dorn, Katharina Klich, Marcos J. Arauzo-Bravo, Martina Radstaak, Simeon Santourlidis, Foued Ghanjati, Teja F. Radke, Olympia E. Psathaki, Gunnar Hargus, Jan Kramer, Martin Einhaus, Jeong Beom Kim, Gesine Kögler, Peter Wernet, Hans R. Schöler, Peter Schlenke, Holm Zaehres
Publikováno v:
Haematologica, Vol 100, Iss 1 (2015)
Epigenetic memory in induced pluripotent stem cells, which is related to the somatic cell type of origin of the stem cells, might lead to variations in the differentiation capacities of the pluripotent stem cells. In this context, induced pluripotent
Externí odkaz:
https://doaj.org/article/7e5bf625b3b14e85b2fa4a5676392965
Autor:
Mikel Arróspide Elgarresta, Daniela Gerovska, Myrian Soto-Gordoa, María L. Jauregui García, Marisa L. Merino Hernández, Marcos J. Araúzo-Bravo
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110816- (2024)
Summary: Multimorbidity (MM) is the co-occurrence of two or more chronic diseases. We provided a dynamic approach revealing the MM complexity constructing a multistep incidence-age model for all patients with MM between 2014 and 2021 in the Basque He
Externí odkaz:
https://doaj.org/article/d03a7ff77aef476ba719805fecaeadb1
Autor:
Neda Kathami, Carolina Moreno-Vicente, Pablo Martín, Jhonatan A. Vergara-Arce, Raquel Ruiz-Hernández, Daniela Gerovska, Ana M. Aransay, Marcos J. Araúzo-Bravo, Sandra Camarero-Espinosa, Ander Abarrategi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Recombinant human bone morphogenetic protein 2 (rhBMP-2) and human bone marrow mesenchymal stromal cells (hBM-MSCs) have been thoroughly studied for research and translational bone regeneration purposes. rhBMP-2 induces bone forma
Externí odkaz:
https://doaj.org/article/21c10d54bce543f89cca0a7db72fcc07
Autor:
Daniela Gerovska, Julie B. Noer, Yating Qin, Quratul Ain, Donjetë Januzi, Matthias Schwab, Otto W. Witte, Marcos J. Araúzo-Bravo, Alexandra Kretz
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-25 (2023)
Abstract Background Numerous genes, including SOD1, mutated in familial and sporadic amyotrophic lateral sclerosis (f/sALS) share a role in DNA damage and repair, emphasizing genome disintegration in ALS. One possible outcome of chromosomal instabili
Externí odkaz:
https://doaj.org/article/2b6b96ec495247b185cba7c323cca0f6
Autor:
Loïc Fiévet, Nicolas Espagnolle, Daniela Gerovska, David Bernard, Charlotte Syrykh, Camille Laurent, Pierre Layrolle, Julien De Lima, Arthur Justo, Nicolas Reina, Louis Casteilla, Marcos J. Araúzo-Bravo, Abderrahim Naji, Jean-Christophe Pagès, Frédéric Deschaseaux
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Native bone marrow (BM) mesenchymal stem/stromal cells (BM-MSCs) participate in generating and shaping the skeleton and BM throughout the lifespan. Moreover, BM-MSCs regulate hematopoiesis by contributing to the hematopoietic stem
Externí odkaz:
https://doaj.org/article/d1b56f19350846568ce3efee6a9a7dee
Autor:
Paula, Aldaz, Maddalen, Otaegi-Ugartemendia, Ander, Saenz-Antoñanzas, Mikel, Garcia-Puga, Manuel, Moreno-Valladares, Juana M, Flores, Daniela, Gerovska, Marcos J, Arauzo-Bravo, Nicolas, Samprón, Ander, Matheu, Estefania, Carrasco-Garcia
Publikováno v:
Scientific Reports
The developmental regulator SOX9 is linked to cancer progression mainly as a result of its role in the regulation of cancer stem cells (CSCs). However, its activity in the differentiated cells that constitute the heterogeneous tumor bulk has not been
Autor:
Simeon Santourlidis, Marcos J. Araúzo-Bravo, Robert T. Brodell, Mohamed Hassan, Marcelo L. Bendhack
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7331 (2024)
Strong epigenetic pan-cancer biomarkers are required to meet several current, urgent clinical needs and to further improve the present chemotherapeutic standard. We have concentrated on the investigation of epigenetic alteration of the hTERT gene, wh
Externí odkaz:
https://doaj.org/article/74244ccaa1934cd1b03c60e1700e088a